Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Satoshi Furuuchi"'
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 18:325-334
The usefulness of the hydrogen–deuterium (H-D) exchange method in the study of drug metabolism was investigated. Metabolite samples of denopamine and promethazine prepared in vitro were introduced to a triple stage quadrupole tandem mass spectromet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4415f46d2cd4a378b018d9bbef152912
https://doi.org/10.1016/s0731-7085(98)00092-2
https://doi.org/10.1016/s0731-7085(98)00092-2
Publikováno v:
Drug Metabolism and Pharmacokinetics. 12:460-474
The absorption, distribution, excretion and metabolism were investigated after a single oral (3 mg/kg) or intravenous (1 mg/kg) administration of 14C-taltirelin to male rats and dogs. 1. The extent of absorption calculated from the ratio of urinary e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b8ff489e03b89e5ef342ab8bd3c3952
https://doi.org/10.2133/dmpk.12.460
https://doi.org/10.2133/dmpk.12.460
Autor:
Ryuichi Arakawa, Takekiyo Matsuo, Satoshi Furuuchi, Noriko Ohashi, Md. Meser Ali, Masa-aki Haga, Gen-etsu Matsubayashi
Publikováno v:
Journal of Mass Spectrometry. 31:861-866
A number of star-burst type tetranuclear complexes denoted by [Met(II)L 2 B] 3 RuX 8 (Met = Ru, Os) were examined by positive electrospray (ES) mass spectrometry, where L is bpy (2,2'-bipyridine) or btfmb (4,4'-bis(trifluoromethyl)-2,2'-bipyridine),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cabe134e87b98dccd11a410fa6bc491
https://doi.org/10.1002/(sici)1096-9888(199608)31:8<861::aid-jms361>3.0.co
https://doi.org/10.1002/(sici)1096-9888(199608)31:8<861::aid-jms361>3.0.co
Autor:
Satoshi Furuuchi
Publikováno v:
Drug Metabolism and Pharmacokinetics. 13:198-199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::794886cd00e95b4a8e8ed876696c0242
https://doi.org/10.2133/dmpk.13.198
https://doi.org/10.2133/dmpk.13.198
Autor:
Shigeyuki Takeyama, Satoshi Furuuchi, Yuji Miura, Hiroshi Endo, Shoichi Harigaya, Masayoshi Yoshikawa
Publikováno v:
YAKUGAKU ZASSHI. 108:989-1000
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b78f84fd0a2aa7b9009db26e9e5b7e
https://doi.org/10.1248/yakushi1947.108.10_989
https://doi.org/10.1248/yakushi1947.108.10_989
Publikováno v:
Chemicalpharmaceutical bulletin. 31(8)
The formation route of the sulfur-containing metabolites of afloqualone [6-amino-2-fluoromethyl-3-(o-tolyl)-4(3H)-quinazolinone, AFQ], a centrally acting muscle relaxant, was studied in rats. When 14C-N-acetyl AFQ 2-mercapturate (AFQM) methyl ester w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69ea283e89db18c6fc89d0c7dde5835
https://pubmed.ncbi.nlm.nih.gov/6652824
https://pubmed.ncbi.nlm.nih.gov/6652824
Publikováno v:
Journal of pharmacobio-dynamics. 6(10)
The disposition and metabolism of afloqualone [6-amino-2-fluoromethyl-3-(o-tolyl)-4(3H)-quinazolinone, AFQ] were studied in monkeys and dogs after oral administration of 14C-AFQ. In both species the blood radioactivity reached a maximum 1 to 2 h afte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b792cfc54653c96cd95a7c6338bfc57f
https://pubmed.ncbi.nlm.nih.gov/6663441
https://pubmed.ncbi.nlm.nih.gov/6663441
Publikováno v:
Journal of pharmacobio-dynamics. 11(5)
Several alkyl ester derivatives or alpha-monoglyceride derivatives of 3H-labeled compounds, i.e. trimetoquinol, TA-594, acetaminophen, naproxen and nicotinic acid, were synthesized and administered orally to rats cannulated in the thoracic duct. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5684cd2ccb5ebb3b18ed9181d43de183
https://pubmed.ncbi.nlm.nih.gov/3171878
https://pubmed.ncbi.nlm.nih.gov/3171878
Autor:
Juko Sugihara, Satoshi Furuuchi
Publikováno v:
Journal of pharmacobio-dynamics. 11(2)
The intestinal absorption process of 1-O-[p-(myristyloxy)-alpha-methylcinnamoyl] glycerol (LK-903), a new hypolipidemic compound, was studied in rats. When 3H-LK-903 or 3H-LKA [3H-p- (myristyloxy)-alpha-methyl cinnamic acid], labeled at the cinnamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570e70d6f1ecf79ac705ecb978636e30
https://pubmed.ncbi.nlm.nih.gov/3379564
https://pubmed.ncbi.nlm.nih.gov/3379564
Publikováno v:
Journal of pharmacobio-dynamics. 11(8)
A series of alpha- and beta-monoglycerides and triglyceride derivatives of naproxen or nicotinic acid were synthesized and investigated in order to elucidate the molecular form of the derivative with properties that enhanced lymphatic absorption. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed644c9f78d06f134a4338288f3447a
https://pubmed.ncbi.nlm.nih.gov/3236213
https://pubmed.ncbi.nlm.nih.gov/3236213