Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Satoshi FUNAYA"'
Autor:
Masato Karayama, Naoki Inui, Yusuke Inoue, Hideki Yasui, Hironao Hozumi, Yuzo Suzuki, Kazuki Furuhashi, Tomoyuki Fujisawa, Noriyuki Enomoto, Kazuhiro Asada, Koji Nishimoto, Masato Fujii, Takashi Matsui, Shun Matsuura, Dai Hashimoto, Mikio Toyoshima, Masaki Ikeda, Hiroyuki Matsuda, Nao Inami, Yusuke Kaida, Satoshi Funayama, Shintaro Ichikawa, Satoshi Goshima, Takafumi Suda
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Immune-related pneumonitis (irP) is one of the most important immune-related adverse events caused by immune checkpoint inhibitors (ICIs). After corticosteroid therapy irP frequently relapses, which can interfere with cancer thera
Externí odkaz:
https://doaj.org/article/bb069103ab2445de9eae9f506ee87ea8
Autor:
Yasuhiko Terada, Tomoki Miyasaka, Ai Nakao, Satoshi Funayama, Shintaro Ichikawa, Tomohiro Takamura, Daiki Tamada, Hiroyuki Morisaka, Hiroshi Onishi
Publikováno v:
Informatics in Medicine Unlocked, Vol 32, Iss , Pp 101030- (2022)
In magnetic resonance imaging (MRI), reducing long scan times is an urgent issue that could be addressed with super-resolution (SR) techniques. Most of the SR networks using deep neural networks (DNNs) have been evaluated only based on numeric metric
Externí odkaz:
https://doaj.org/article/428e9a21fb724e379a8da04166515ec0
Publikováno v:
The Journal of Reproduction and Development, Vol 69, Iss 3, Pp 178-182 (2023)
Linker histone variants regulate higher-order chromatin structure and various cellular processes. It has been suggested that linker histone variant H1a loosens chromatin structure and activates transcription. However, its role in early mouse developm
Externí odkaz:
https://doaj.org/article/bbda87dfd1a342aabbea24021deed378
Autor:
Satoshi Funaya, Yuria Kawabata, Kenta Sugie, Ken-ichiro Abe, Yutaka Suzuki, Masataka G. Suzuki, Fugaku Aoki
Publikováno v:
Reproduction (Cambridge, England). 164(2)
In oocytes, chromatin structure is loosened during their growth, which seems to be essential for the establishment of competence to accomplish the maturation and further development after fertilization. This paper shows that a linker histone variant,
Autor:
Satoshi Funaya, Yuria Kawabata, Kenta Sugie, Ken-ichiro Abe, Yutaka Suzuki, Suzuki, Masataka G., Fugaku Aoki
Publikováno v:
Reproduction; Aug2022, Vol. 164 Issue 2, p19-29, 11p
Autor:
Fugaku Aoki, Satoshi Funaya, Masataka G. Suzuki, Kenta Sugie, Machika Kawamura, Toshinobu Nakamura
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
After fertilization, the zygotic genome is activated through two phases, minor zygotic activation (ZGA) and major ZGA. Recently, it was suggested that DUX is expressed during minor ZGA and activates some genes during major ZGA. However, it has not be
Autor:
Masataka G. Suzuki, Kunihiko Naito, Yuki Hashioka, Masatoshi Ooga, Wataru Fujii, Fugaku Aoki, Satoshi Funaya
Publikováno v:
Biochemical and Biophysical Research Communications. 500:583-588
During oogenesis, oocytes prepare for embryonic development following fertilization. The mechanisms underlying this process are still unknown. Recently, it has been suggested that a loosened chromatin structure is involved in pluripotency and totipot
Asymmetrical deposition and modification of histone H3 variants are essential for zygote development
Publikováno v:
Life Science Alliance
A low level of H3.1/2 deposition in the perinucleolar regions of male pronuclei in zygotes prevents accumulation of H3.1/2K27me3 modification which has detrimental effect on DNA replication.
The pericentromeric heterochromatin of one-cell embryo
The pericentromeric heterochromatin of one-cell embryo
Autor:
Satoshi Funaya, Fugaku Aoki
Publikováno v:
The Journal of Reproduction and Development
After fertilization, the genomes derived from an oocyte and spermatozoon are in a transcriptionally silent state before becoming activated at a species-specific time. In mice, the initiation of transcription occurs at the mid-one-cell stage, which re
Publikováno v:
Life Science Alliance; Aug2021, Vol. 4 Issue 8, p1-13, 13p