Zobrazeno 1 - 10
of 413
pro vyhledávání: '"Satoshi, Yamazaki"'
Autor:
Satoshi Kaito, Kazumasa Aoyama, Motohiko Oshima, Akiho Tsuchiya, Makiko Miyota, Masayuki Yamashita, Shuhei Koide, Yaeko Nakajima-Takagi, Hiroko Kozuka-Hata, Masaaki Oyama, Takao Yogo, Tomohiro Yabushita, Ryoji Ito, Masaya Ueno, Atsushi Hirao, Kaoru Tohyama, Chao Li, Kimihito Cojin Kawabata, Kiyoshi Yamaguchi, Yoichi Furukawa, Hidetaka Kosako, Akihide Yoshimi, Susumu Goyama, Yasuhito Nannya, Seishi Ogawa, Karl Agger, Kristian Helin, Satoshi Yamazaki, Haruhiko Koseki, Noriko Doki, Yuka Harada, Hironori Harada, Atsuya Nishiyama, Makoto Nakanishi, Atsushi Iwama
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract DNA hypomethylating agents (HMAs) are used for the treatment of myeloid malignancies, although their therapeutic effects have been unsatisfactory. Here we show that CRISPR-Cas9 screening reveals that knockout of topoisomerase 1-binding argin
Externí odkaz:
https://doaj.org/article/d5c4ccd82b76400cb577a39dab027bde
Autor:
Masahiro Tsuboi, Haruyasu Murakami, Hideyuki Harada, Tomotaka Sobue, Tomohiro Kato, Shinji Atagi, Takaaki Tokito, Tadashi Mio, Hirofumi Adachi, Toshiyuki Kozuki, Takashi Sone, Masahiro Seike, Shinichi Toyooka, Hiroshi Kitagawa, Ryo Koto, Satoshi Yamazaki, Hidehito Horinouchi
Publikováno v:
Thoracic Cancer, Vol 15, Iss 20, Pp 1541-1552 (2024)
Abstract Background To elucidate the treatment and surgery outcomes with or without perioperative therapies in Japanese patients with clinical stage III non‐small cell lung cancer (NSCLC) in real‐world settings. Methods We performed subset analys
Externí odkaz:
https://doaj.org/article/301b08279edf4e2cb9aa89a30fb1a6a3
Autor:
Xinyi Zeng, Teh-Wei Wang, Kiyoshi Yamaguchi, Seira Hatakeyama, Satoshi Yamazaki, Eigo Shimizu, Seiya Imoto, Yoichi Furukawa, Yoshikazu Johmura, Makoto Nakanishi
Publikováno v:
Molecular Metabolism, Vol 84, Iss , Pp 101943- (2024)
Objectives: Adipose tissue is an endocrine and energy storage organ composed of several different cell types, including mature adipocytes, stromal cells, endothelial cells, and a variety of immune cells. Adipose tissue aging contributes to the pathog
Externí odkaz:
https://doaj.org/article/d4df8a00e52b49dc89a15ccb72df509b
Autor:
Emi Sugimoto, Jingmei Li, Yasutaka Hayashi, Kohei Iida, Shuhei Asada, Tsuyoshi Fukushima, Moe Tamura, Shiori Shikata, Wenyu Zhang, Keita Yamamoto, Kimihito Cojin Kawabata, Tatsuya Kawase, Takeshi Saito, Taku Yoshida, Satoshi Yamazaki, Yuta Kaito, Yoichi Imai, Tamami Denda, Yasunori Ota, Tomofusa Fukuyama, Yosuke Tanaka, Yutaka Enomoto, Toshio Kitamura, Susumu Goyama
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Immunotherapy has attracted considerable attention as a therapeutic strategy for cancers including acute myeloid leukemia (AML). In this study, we found that the development of several aggressive subtypes of AML is slower in Rag2 −/− mic
Externí odkaz:
https://doaj.org/article/5b6b8d5e72fb4e78b3b3547dd6332877
Autor:
Teiko Kawahigashi, Shoya Iwanami, Munetomo Takahashi, Joydeep Bhadury, Shingo Iwami, Satoshi Yamazaki
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0292575 (2024)
Hematopoietic stem cells (HSCs) are somatic stem cells that continuously generate lifelong supply of blood cells through a balance of symmetric and asymmetric divisions. It is well established that the HSC pool increases with age. However, not much i
Externí odkaz:
https://doaj.org/article/f0ff85763d7441fe8baa4b24cc990162
Autor:
Yuko Fujii, Hideki Matsumura, Akihiko Shirasu, Hyogo Nakakura, Satoshi Yamazaki, Tetsufumi Kanazawa, Nanako Saito, Hajime Hirano, Haruhito Azuma, Kandai Nozu, Akira Ashida
Publikováno v:
Renal Replacement Therapy, Vol 9, Iss 1, Pp 1-4 (2023)
Abstract Background Autism spectrum disorder (ASD) is a common communication disorder, with an incidence rate of 3%. In most cases, clinicians can diagnose ASD in a single outpatient visit. However, in the case of ASD patients without intellectual di
Externí odkaz:
https://doaj.org/article/453829c51fed4e728fd6199c48e5e8d7
Autor:
Satoshi Yamazaki, Yuto Nakajima
Publikováno v:
IEEE Access, Vol 11, Pp 145320-145330 (2023)
This paper proposes an experimental approximation formula for battery lifetime considering real Sigfox node behavior for smart agriculture as an internet of things (IoT) use case outdoors. To achieve this, a Sigfox-based sensor node is first develope
Externí odkaz:
https://doaj.org/article/a0eec3beff6442d4b31b0be219dbda08
Autor:
Naoki Itokawa, Motohiko Oshima, Shuhei Koide, Naoya Takayama, Wakako Kuribayashi, Yaeko Nakajima-Takagi, Kazumasa Aoyama, Satoshi Yamazaki, Kiyoshi Yamaguchi, Yoichi Furukawa, Koji Eto, Atsushi Iwama
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Haematopoietic stem cells (HSCs) exhibit considerable cell-intrinsic changes with age. Here the authors demonstrate that differentially accessible regions in aged HSC chromatin are enriched for stress-responsive enhancers and act as an epigenetic hub
Externí odkaz:
https://doaj.org/article/ab77cfdec83c409e9e21ac09da3b7aa9
Autor:
Muneyuki Koyama, Kazuo Matai, Akiyoshi Kinoshita, Shunta Ishizaki, Kouhei Okazaki, Masaya Inoue, Keita Kodera, Yuki Hiramoto, Toshihiko Arima, Nobuhiro Saito, Miki Kobayashi, Satoshi Yamazaki, Ken Eto
Publikováno v:
Trauma Case Reports, Vol 43, Iss , Pp 100761- (2023)
Traumatic intrathoracic foreign bodies are said to occur in many cases when the patient himself/herself is aware of the trauma. However, at the time of injury, the patient may sometimes be accompanied by loss of consciousness. We report a case of tra
Externí odkaz:
https://doaj.org/article/22d4c29c894443a0997226039d3e242d
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Bone marrow chimaeric mice are a valuable tool in research, but require myeloablative conditioning. Here the authors demonstrate efficient FACS-free enrichment of haematopoietic stem and progenitor cells for transplantation into unconditioned recipie
Externí odkaz:
https://doaj.org/article/df8da65f907e470fb2d843f89f224190