Involvement of Mediterranean fever gene mutations in colchicine-responsive enterocolitis: a retrospective cohort studyResearch in context

Autor: Hiroshi Nakase, Kohei Wagatsuma, Taku Kobayashi, Takayuki Matsumoto, Motohiro Esaki, Kenji Watanabe, Reiko Kunisaki, Teruyuki Takeda, Katsuhiro Arai, Takashi Ibuka, Dai Ishikawa, Yuichi Matsuno, Hirotake Sakuraba, Nobuhiro Ueno, Kaoru Yokoyama, Masayuki Saruta, Ryota Hokari, Junji Yokoyama, Shu Tamano, Masanori Nojima, Tadakazu Hisamatsu, Shusaku Yoshikawa, Sohachi Nanjo, Akira Andoh, Takeshi Kimura, Makoto Ooi, Ryosuke Kiyomori, Nobuo Aoyama, Fumihito Hirai, Atsushi Yamaushi, Masanao Nakamura, Fumikazu Koyama, Shuhei Hosomi, Kazuki Kakimoto, Satoshi Motoya, Ryosuke Sakemi, Hideo Suzuki, Tadashi Hosoya, Ken Takeuchi, Manabu Shiraki, Hideyuki Koide, Ichiro Takeuchi, Yosuke Furui, Kento Yoshida, Ayaka Minemura, Asami Matsumoto, Kentaro Oka

Publikováno v: EBioMedicine, Vol 110, Iss , Pp 105454- (2024)

Summary: Background: The involvement of Mediterranean fever (MEFV) gene mutations in patients with inflammatory bowel disease unclassified (IBDU) remains unclear. This study aimed to determine the clinical characteristics and responsiveness to colchi

Externí odkaz: https://doaj.org/article/65aa18ec7b90480d9069fe49057c33ed

Final Analysis of COVID-19 Patients With Inflammatory Bowel Disease in Japan (J-COSMOS): A Multicenter Registry Cohort Study

Autor: Hiroshi Nakase, Yuki Hayashi, Yoshihiro Yokoyama, Takayuki Matsumoto, Minoru Matsuura, Hideki Iijima, Katsuyoshi Matsuoka, Naoki Ohmiya, Shunji Ishihara, Fumihito Hirai, Daiki Abukawa, Tadakazu Hisamatsu, Makoto Sasaki, Masahiro Iizuka, Mikihiro Fujiya, Fukunori Kinjo, Shiro Nakamura, Noriko Kamata, Yuri Etani, Fumiaki Ueno, Sakiko Hiraoka, Takeo Kondo, Takashi Kagaya, Makoto Naganuma, Kiyonori Kobayashi, Taku Kobayashi, Shuji Yamamoto, Yuji Naito, Yoki Furuta, Keichi Mitsuyama, Yu Hashimoto, Katsuhiro Arai, Shingo Kato, Itaru Iwama, Motohiro Esaki, Hiroki Tanaka, Satoshi Motoya, Atsuo Maemoto, Toshifumi Ashida, Nobuaki Nishimata, Shigeaki Aono, Akira Andoh, Hironori Yamamoto, Toshiaki Shimizu, Maeda Yasuharu, Kenji Kinoshita, Katuyuki Fukuda, Jun Kato, Ken Takeuchi, Masakazu Nagahori, Masakatsu Fukuzawa, Masayuki Saruta, Takayoshi Suzuki, Michio Itabashi, Masaru Shinozaki, Soichiro Ishihara, Naoki Yoshimura, Yoichi Kakuta, Kenichi Takahashi, Keiichi Tominaga, Ryosuke Sakemi, Sohachi Nanjo, Shusaku Yoshikawa, Keiji Ozeki, Ayako Fuchigami, Takehiko Katsurada, Kenji Watanabe, Hirotake Sakuraba, Takashi Hisabe, Shigeru Iwase, Ryota Hokari, Katsuhiko Nakai, Takeshi Ueda, Shojiro Yamamoto, Kazutaka Koganei, Reiko Kunisaki, Akira Hokama

Publikováno v: Gastro Hep Advances, Vol 2, Iss 8, Pp 1056-1065 (2023)

Background and Aims: Japan has experienced 8 waves of the coronavirus disease 2019 (COVID-19) outbreak over the past 3 years, resulting in an increasing number of deaths and incidence of severe infections. This study aimed to analyze the data from th

Externí odkaz: https://doaj.org/article/6dc0fa435835412099a962069329f0e1

Effectiveness and factors associated with response to golimumab in Japanese patients with ulcerative colitis in real clinical practice: Phoenix Study

Autor: Daisuke Hirayama, Satoshi Motoya, Toshifumi Ashida, Katsuyoshi Ando, Mikihiro Fujiya, Takahiro Ito, Shigeru Furukawa, Atsuo Maemoto, Takehiko Katsurada, Shiro Hinotsu, Noriko Sato, Naomi Mizuno, Yoshiko Ikawa, Hiroshi Nakase

Publikováno v: Inflammatory Intestinal Diseases (2023)

Abstract Introduction: There have been limited reports on the clinical efficacy of golimumab (GLM) in Japanese patients with ulcerative colitis (UC) in real clinical practice. This study aimed to explore the real-life effectiveness and factors associ

Externí odkaz: https://doaj.org/article/4c68dbc870ca4af0b49a58164f4bdb7d

Decoding the diversity of killer immunoglobulin-like receptors by deep sequencing and a high-resolution imputation method

Autor: Saori Sakaue, Kazuyoshi Hosomichi, Jun Hirata, Hirofumi Nakaoka, Keiko Yamazaki, Makoto Yawata, Nobuyo Yawata, Tatsuhiko Naito, Junji Umeno, Takaaki Kawaguchi, Toshiyuki Matsui, Satoshi Motoya, Yasuo Suzuki, Hidetoshi Inoko, Atsushi Tajima, Takayuki Morisaki, Koichi Matsuda, Yoichiro Kamatani, Kazuhiko Yamamoto, Ituro Inoue, Yukinori Okada

Publikováno v: Cell Genomics, Vol 2, Iss 3, Pp 100101- (2022)

Summary: The killer cell immunoglobulin-like receptor (KIR) recognizes human leukocyte antigen (HLA) class I molecules and modulates the function of natural killer cells. Despite its role in immunity, the complex genomic structure has limited a deep

Externí odkaz: https://doaj.org/article/90501fcf80d34f2380420ddb63a6f8b7

Safety and effectiveness of granulocyte and monocyte adsorptive apheresis in patients with inflammatory bowel disease in special situations: a multicentre cohort study

Autor: Satoshi Motoya, Hiroki Tanaka, Tomoyoshi Shibuya, Taro Osada, Takayuki Yamamoto, Hitoshi Hongo, Chiemi Mizuno, Daisuke Saito, Nobuo Aoyama, Toshihisa Kobayashi, Hiroaki Ito, Satoshi Tanida, Masanori Nojima, Seiichiro Kokuma, Eiji Hosoi

Publikováno v: BMC Gastroenterology, Vol 19, Iss 1, Pp 1-15 (2019)

Abstract Background The available information on granulocyte and monocyte adsorptive apheresis (GMA) in patients with inflammatory bowel disease (IBD) under special situations remains unclear. We conducted a retrospective, multicentre cohort study to

Externí odkaz: https://doaj.org/article/6a8f806b90994ad9a259a88840c85042