Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Satoru Usami"'
Autor:
Hirohiko Motoki, Izuru Masuda, Shinji Yasuno, Koji Oba, Wataru Shoin, Satoru Usami, Yoshihiko Saito, Masako Waki, Mitsuhisa Komatsu, Kenji Ueshima, Yasuaki Nakagawa, Cheol Son, Shin Yonemitsu, Shinya Hiramitsu, Manako Konda, Katsuya Onishi, Koichiro Kuwahara
Publikováno v:
ESC Heart Failure, Vol 7, Iss 5, Pp 3134-3141 (2020)
Abstract Aims A sodium glucose cotransporter 2 (SGLT2) inhibitor was recently found to reduce heart failure hospitalization in the EMPA‐REG OUTCOME trial. We have hypothesized that autonomic nerve activity may be modulated by SGLT2 inhibition. The
Externí odkaz:
https://doaj.org/article/5e1c84e0e3d24efd9b90c450a8cfb7b3
Autor:
Koji Oba, Mitsuhisa Komatsu, Wataru Shoin, Yasuaki Nakagawa, Satoru Usami, Yoshihiko Saito, Shin Yonemitsu, Izuru Masuda, Kenji Ueshima, Shinya Hiramitsu, Koichiro Kuwahara, Masako Waki, Cheol Son, Manako Konda, Katsuya Onishi, Shinji Yasuno, Hirohiko Motoki
Publikováno v:
ESC Heart Failure, Vol 7, Iss 5, Pp 3134-3141 (2020)
Aims A sodium glucose cotransporter 2 (SGLT2) inhibitor was recently found to reduce heart failure hospitalization in the EMPA‐REG OUTCOME trial. We have hypothesized that autonomic nerve activity may be modulated by SGLT2 inhibition. The current s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810bf119f24fd65ca19f00d9e31d9362
https://doaj.org/article/5e1c84e0e3d24efd9b90c450a8cfb7b3
https://doaj.org/article/5e1c84e0e3d24efd9b90c450a8cfb7b3
Autor:
Kei Kobayashi, Satoru Usami, Masakazu Kashihara, Toshiyuki Komori, Noriko Ishikawa, Rise Kum, Norio Kato, Natsuko Uekawa, Naoki Takemori, Yuejin Sun, Paul Oeller, Esteban Bortiri, Nicholas J. Bate, Toshihiko Komari, Yukoh Hiei, Kimberly White
Publikováno v:
Theoretical and Applied Genetics. 133:1291-1301
Novel drought tolerance genes were identified by screening thousands of random genomic fragments from grass species in transgenic rice. Identification of agronomically important genes is a critical step for crop breeding through biotechnology. Multip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c6d19ce0a37600c1e7b12e366a7690
https://doi.org/10.1007/s00122-020-03548-6
https://doi.org/10.1007/s00122-020-03548-6
Autor:
Manako Konda, Masako Waki, Shinya Hiramitsu, Katsuya Onishi, Shinji Yasuno, Shin Yonemitsu, Hirohiko Motoki, Koichiro Kuwahara, Wataru Shoin, Cheol Son, Izuru Masuda, Kenji Ueshima, Yasuaki Nakagawa, Satoru Usami, Mitsuhisa Komatsu, Koji Oba, Yoshihiko Saito
Background: A sodium glucose cotransporter 2 (SGLT2) inhibitor was recently found to reduce heart failure hospitalization in the EMPA-REG OUTCOMES trial. We have hypothesized that autonomic nerve activity may be modulated by SGLT2 inhibition. The cur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da23c744e7f60735a75693fcf637d0f5
https://doi.org/10.21203/rs.2.23750/v1
https://doi.org/10.21203/rs.2.23750/v1
Autor:
Kazuwa Nakao, Satoru Usami, Toshio Nishikimi, Yasuaki Nakagawa, Koichiro Kuwahara, Yoshihiro Kuwabara, Shinji Yasuno, Kenji Ueshima, Masaki Harada, Hideyuki Kinoshita, Chinatsu Yamada
Publikováno v:
British Journal of Pharmacology. 170:1384-1395
Background and Purpose Angiotensin II has been implicated in the development of various cardiovascular ailments, including cardiac hypertrophy and heart failure. The fact that inhibiting its signalling reduced the incidences of both sudden cardiac de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8933a63a6965551922bb1d22b3c1c233
https://doi.org/10.1111/bph.12328
https://doi.org/10.1111/bph.12328
Autor:
Minoru Takaoka, Kenji Ueshima, Takahiro Seno, Kenji Sobue, Yutaka Kawahito, Yasuaki Nakagawa, Ryozo Nagai, Akinori Kimura, Takeya Minami, Shinji Yasuno, Koichiro Kuwahara, Hiroyasu Nakano, Masataka Sata, Chinatsu Yamada, Junko Shibata, Yuko Yamada, Yoshihiro Kuwabara, Satoru Usami, Kazuhiro Nakao, Kazuwa Nakao, Hideyuki Kinoshita, Toshio Nishikimi
Publikováno v:
The EMBO Journal. 31:4428-4440
Myocardin-related transcription factor (MRTF)-A is a Rho signalling-responsive co-activator of serum response factor (SRF). Here, we show that induction of MRTF-A expression is key to pathological vascular remodelling. MRTF-A expression was significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::410ea2bb998f66a981c05f6c00022cd6
https://doi.org/10.1038/emboj.2012.296
https://doi.org/10.1038/emboj.2012.296
Autor:
Satoru Usami, Koichiro Kuwahara, Yuko Yamada, Chinatsu Yamada, Masao Murakami, Toshio Nishikimi, Leo Hata, Kazuwa Nakao, Masataka Fujiwara, Yasuaki Nakagawa, Kazuhiro Nakao, Takeya Minami, Kenji Ueshima, Shinji Yasuno, Yoshihiro Kuwabara, Hideyuki Kinoshita
Publikováno v:
Journal of Molecular and Cellular Cardiology. 50:972-981
Neuron-restrictive silencer factor (NRSF) is a zinc-finger transcription factor that binds to specific DNA sequences (NRSE) to repress transcription. By down-regulating the transcription of its target genes, NRSF contributes to the regulation of vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875bff9aeb8d039de4c815dd35a452b9
https://doi.org/10.1016/j.yjmcc.2011.01.017
https://doi.org/10.1016/j.yjmcc.2011.01.017
Autor:
Masataka Fujiwara, Yoshihiro Kuwabara, Zhong Jian, Hideyuki Kinoshita, Xianglu Rong, Yuhao Li, Kazuwa Nakao, Koichiro Kuwahara, Yasuo Mori, Motohiro Nishida, Yuko Yamada, Satoru Usami, Ryuji Inoue, Kenji Ueshima, Hitoshi Kurose, Yasuaki Nakagawa, Takeya Minami, Shigeki Kiyonaka
Publikováno v:
Circulation Research. 106:1849-1860
Rationale : Atrial and brain natriuretic peptides (ANP and BNP, respectively) exert antihypertrophic effects in the heart via their common receptor, guanylyl cyclase (GC)-A, which catalyzes the synthesis of cGMP, leading to activation of protein kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ac4df1309775a6c0849cfe44605f4f
https://doi.org/10.1161/circresaha.109.208314
https://doi.org/10.1161/circresaha.109.208314
Autor:
Takeshi Yamamoto, Hiroshi Tsukamoto, Satoru Usami, Hitomi Kajiwara, Naomi Oka, Masako Tsunashima, Yuji Ishida, Yoshimitsu Takakura
Publikováno v:
Journal of Biotechnology. 145:317-322
Tamavidin 2 is a fungal avidin-like protein that binds biotin with high affinity and is highly produced in soluble form in Escherichia coli. By contrast, widely used biotin-binding proteins avidin and streptavidin are rarely produced in soluble form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a07f6d4d9c7494e66859f8fd5c3fd2a
https://doi.org/10.1016/j.jbiotec.2009.12.012
https://doi.org/10.1016/j.jbiotec.2009.12.012
Autor:
Takuya Yamazaki, Osamu Nishiyama, Satoru Usami, Kazuwa Nakao, Shinji Yasuno, Akira Yamashina, Tsunehiko Nishimura, Kenji Ueshima
Publikováno v:
Annals of Nuclear Medicine. 23:849-854
Objectives We assessed whether a combination of summed stress scores (SSS) using exercise myocardial perfusion SPECT (Ex-SPECT) and maximal heart rate accurately predicts cardiac events through a sub-analysis of J-ACCESS (Japanese Assessment of Cardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46cf1e294294bb2ab0e8ebde951ebcbf
https://doi.org/10.1007/s12149-009-0315-8
https://doi.org/10.1007/s12149-009-0315-8