Výsledky vyhledávání - "Satoru Senju"

Akademický článek

Dengue virus susceptibility in novel immortalized myeloid cells

Autor: Atsushi Yamanaka, Kazuo Miyazaki, Jun Shimizu, Satoru Senju

Publikováno v: Heliyon, Vol 6, Iss 11, Pp e05407- (2020)

Human dendritic cells (DCs) are the main target cells of dengue virus (DENV). Because humans injected with even a small volume of DENV from mosquito saliva display a high level of viremia, DCs are expected to be highly susceptible to DENV. In the pre

Externí odkaz: https://doaj.org/article/fa67c785eb3d459c8fd206e290491a83

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Akademický článek

Generation of GM-CSF-producing antigen-presenting cells that induce a cytotoxic T cell-mediated antitumor response

Autor: Hiroaki Mashima, Rong Zhang, Tsuyoshi Kobayashi, Yuichiro Hagiya, Hirotake Tsukamoto, Tianyi Liu, Tatsuaki Iwama, Masateru Yamamoto, Chiahsuan Lin, Ryusuke Nakatsuka, Yuta Mishima, Noriko Watanabe, Takashi Yamada, Satoru Senju, Shin Kaneko, Alimjan Idiris, Tetsuya Nakatsura, Hideki Ohdan, Yasushi Uemura

Publikováno v: OncoImmunology, Vol 9, Iss 1 (2020)

Immunotherapy using dendritic cells (DCs) is a promising treatment modality for cancer. However, the limited number of functional DCs from peripheral blood has been linked to the unsatisfactory clinical efficacies of current DC-based cancer immunothe

Externí odkaz: https://doaj.org/article/97057ff2950a43e8858f76e78e9bec65

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Akademický článek

Inflammatory state exists in familial amyloid polyneuropathy that may be triggered by mutated transthyretin

Autor: Genki Suenaga, Tokunori Ikeda, Teruaki Masuda, Hiroaki Motokawa, Taro Yamashita, Kotaro Takamatsu, Yohei Misumi, Mitsuharu Ueda, Hirotaka Matsui, Satoru Senju, Yukio Ando

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)

Abstract The relationship between familial amyloid polyneuropathy (FAP), which is caused by mutated transthyretin (TTR), and inflammation has only recently been noted. To determine whether inflammation is present in FAP carriers and patients, serum i

Externí odkaz: https://doaj.org/article/5dbb39c113ac4fe3a3a9ceef389c870f

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Akademický článek

Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells

Publikováno v: Cell Reports, Vol 29, Iss 1, Pp 162-175.e9 (2019)

Summary: Type I interferons (IFNs) play important roles in antitumor immunity. We generated IFN-α-producing cells by genetically engineered induced pluripotent stem cell (iPSC)-derived proliferating myeloid cells (iPSC-pMCs). Local administration of

Externí odkaz: https://doaj.org/article/10e8ff19e2ed49ff9f9f1af0099b33bd

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