Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Satoru Niwa"'
Autor:
Thomas Hoyler, Bettina Bannert, Cédric André, Damian Beck, Thomas Boulay, David Buffet, Nadja Caesar, Thomas Calzascia, Janet Dawson, Diego Kyburz, Robert Hennze, Christine Huppertz, Amanda Littlewood-Evans, Pius Loetscher, Kirsten D. Mertz, Satoru Niwa, Gautier Robert, James S. Rush, Giulia Ruzzante, Sophie Sarret, Thomas Stein, Ismahane Touil, Grazyna Wieczorek, Geraldine Zipfel, Stuart Hawtin, Tobias Junt
Publikováno v:
JCI Insight, Vol 7, Iss 13 (2022)
IL-1 receptor-activated kinase 1 (IRAK1) is involved in signal transduction downstream of many TLRs and the IL-1R. Its potential as a drug target for chronic inflammatory diseases is underappreciated. To study its functional role in joint inflammatio
Externí odkaz:
https://doaj.org/article/6fc6e2c6d008483f99d660e2370be0ce
Autor:
Kea Martin, Ursula Junker, Elaine Tritto, Esther Sutter, Tina Rubic-Schneider, Hannah Morgan, Satoru Niwa, Jianping Li, Achim Schlapbach, Dana Walker, Marc Bigaud, Christian Beerli, Amanda Littlewood-Evans, Bettina Rudolph, Marc Laisney, David Ledieu, Karen Beltz, Jean Quancard, Frédéric Bornancin, Natasa Zamurovic Ribrioux, Thomas Calzascia
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Genetic disruption or short-term pharmacological inhibition of MALT1 protease is effective in several preclinical models of autoimmunity and B cell malignancies. Despite these protective effects, the severe reduction in regulatory T cells (Tregs) and
Externí odkaz:
https://doaj.org/article/92eee817000748258e9659af159c4926
Autor:
Satoru Niwa, Yousuke Hirano, Ting Wang, Takashi Ochi, Naoki Inagaki, Koichi Shudo, Hiroichi Nagai
Publikováno v:
Allergology International, Vol 49, Iss 1, Pp 75-81 (2000)
Some retinoids show an anti-inflammatory action through regulation of transcription of various genes. In the present study, the inhibitory effect of 4-((5,6,7,8- tetrahydro-5,5,8,8-tetramethyl-2-naphthyl) carbamoyl) benzoic acid (Am-80), a synthetic
Externí odkaz:
https://doaj.org/article/0415ace8f5e846c89d59f406c001b0d6
Autor:
K Usuda, Ken Okumura, Kazumasa Sonoda, Masa-aki Kawashiri, Hayato Tada, Teiichi Yamane, Ryuta Watanabe, Takeshi Kato, Yasuo Okumura, Yukihiko Momiyama, Hidemori Hayashi, Nobuhisa Hagiwara, Kazuhiro Satomi, Ikutaro Nakajima, Koichiro Ejima, Naoya Matsumoto, Shinya Suzuki, Masayuki Takamura, Wataru Shimizu, Yoshinao Yazaki, Takayuki Otsuka, Kyoko Soejima, Kenji Sakata, Michifumi Tokuda, Junjiroh Koyama, Masaru Arai, Kenshi Hayashi, Yu-ki Iwasaki, Yuji Watari, Noriko Nonoguchi, Soichiro Usui, Katsuaki Yokoyama, Mitsuru Takami, Shiro Nakahara, Hiroshi Furusho, Koji Kumagai, Koichi Nagashima, Kojiro Tanimoto, Tomoo Harada, Hidehira Fukaya, Masahide Harada, Toyonobu Tsuda, Akio Hirata, Hiroshi Hayashi, Satoru Niwa, Masato Murakami, Masaomi Kimura, Masaru Inoue
Publikováno v:
Heart and Vessels. 37:327-336
The impact of catheter ablation for atrial fibrillation (AF) on cardiovascular events and mortality is controversial. We investigated the impact of sinus rhythm maintenance on major adverse cardiac and cerebrovascular events after AF ablation from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a43e4e7bceed25c9fe485612f765f56e
https://doi.org/10.1007/s00380-021-01929-5
https://doi.org/10.1007/s00380-021-01929-5
Autor:
Hirofumi Takemura, Tetsuo Nishikawa, Toshinori Higashikata, Hiroki Kato, Kenji Sakata, Satoru Niwa, Kenji Ino, Shohei Yoshida, Masa-aki Kawashiri, Atsushi Nohara, Mika Mori, Hayato Tada, Tamami Nakagawa-Kamiya, Masayuki Takamura
Publikováno v:
J Cardiol Cases
We present a case of a Japanese patient with familial hypercholesterolemia (FH) caused by a low-density lipoprotein (LDL) receptor gene mutation. A 47-year-old female was referred to our hospital due to her systemic xanthomatosis associated with elev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7040fc6e9613bf4d175d8f8003191628
https://doi.org/10.1016/j.jccase.2020.06.012
https://doi.org/10.1016/j.jccase.2020.06.012
Autor:
Hidemori Hayashi, Masahide Harada, Shiro Nakahara, Toyonobu Tsuda, Nobuhisa Hagiwara, Akio Hirata, Kenshi Hayashi, Takayuki Otsuka, Teiichi Yamane, Yukihiko Momiyama, Satoru Niwa, Ken Okumura, Wataru Shimizu, Takeshi Kato, Koichi Nagashima, Masa-aki Kawashiri, Masayuki Takamura, Yasuo Okumura, Masaomi Kimura, Kenji Sakata, Masaru Inoue, Hayato Tada, Naoya Matsumoto, Masato Murakami, Hiroshi Furusho, Kazumasa Sonoda, Tomoo Harada, Kyoko Soejima, Koji Kumagai, Kazuhiro Satomi, K Usuda, Hidehira Fukaya, Soichiro Usui, Mitsuru Takami, Yuji Watari
Introduction: The impact of catheter ablation for atrial fibrillation (AF) on cardiovascular events and mortality is controversial. We investigated the impact of sinus rhythm maintenance on major adverse cardiac and cerebrovascular events after AF ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c089906cbf89ff4d9f69853ae0e2ee57
https://doi.org/10.22541/au.161058060.07089740/v1
https://doi.org/10.22541/au.161058060.07089740/v1
Autor:
K Usuda, Yasuo Okumura, Hayato Tada, Takeshi Kato, K Takeuchi, Satoru Niwa, Kenshi Hayashi, Hiroshi Furusho, Masayuki Takamura, Toyonobu Tsuda, Koichi Nagashima
Publikováno v:
European Heart Journal. 41
Background High plasma B-Type natriuretic peptide (BNP) level is associated with cardiac events or stroke in patients with atrial fibrillation (AF). However, it is still unknown whether BNP predicts worse clinical outcomes after catheter ablation ofA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46bbae704d2fcb743c17a1492f42c012
https://doi.org/10.1093/ehjci/ehaa946.0604
https://doi.org/10.1093/ehjci/ehaa946.0604
Autor:
Takeshi Kato, Masayuki Takamura, K Takeuchi, Hiroshi Furusho, Noboru Fujino, Kenji Sakata, S Usui, Masa-aki Kawashiri, Satoru Niwa, Kenshi Hayashi, Toyonobu Tsuda
Publikováno v:
European Heart Journal. 41
Background The genetic bases of cardiac conduction-system disease (CCSD) range from ion channelopathies to mutations in many other genes. Genome-wide association studies have shown common variants in SCN10A influence cardiac conduction. However, it h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cf37cb3c068ad83866b5b30d217a6ed
https://doi.org/10.1093/ehjci/ehaa946.0341
https://doi.org/10.1093/ehjci/ehaa946.0341
Autor:
Hiroshi Furusho, K Takeuchi, Toyonobu Tsuda, Kenji Sakata, Masayuki Takamura, Takeshi Kato, K Usuda, Satoru Niwa, AF Frontier Ablation Registry, Hayato Tada, Yasuo Okumura, Koichi Nagashima, S Usui, Masa-aki Kawashiri, Kenshi Hayashi
Publikováno v:
European Heart Journal. 41
Background Recent observational studies have suggested that catheter ablation for atrial fibrillation (AF) is significantly associated with reduced risk for stroke, cardiovascular events and all-cause death. However, little is known whether late recu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08b8aa34b65d68fe98b3c2aae0d7dfec
https://doi.org/10.1093/ehjci/ehaa946.0603
https://doi.org/10.1093/ehjci/ehaa946.0603
Autor:
Tao Jiang, Stuart Hawtin, Claudia Betschart, Tobias Junt, Pierre-Yves Michellys, Maureen Ibanez, Satoru Niwa, Jillian Maginnis, Zhang Yi, Geraldine Collignon Zipfel, James S. Rush, Wendy Richmond, Daniel Mutnick, Perry Gordon, Bishnu P. Nayak, David Buffet, Xue-Feng Zhu, Bo Liu, Thomas Knoepfel, Phil B. Alper, Una McKeever, Jonathan A. Deane, Syka Peter, Janice Hampton
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(17)
Antagonism of the Toll-like receptors (TLRs) 7 and TLR8 has been hypothesized to be beneficial to patients suffering from autoimmune conditions. A phenotypic screen for small molecule antagonists of TLR7/8 was carried out in a murine P4H1 cell line.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec134d2986300d8633e09dd727ca587
https://pubmed.ncbi.nlm.nih.gov/32738975
https://pubmed.ncbi.nlm.nih.gov/32738975