Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Satoru Kon"'
Autor:
Daisuke Uno, Kazuhira Endo, Tomomi Yoshikawa, Nobuyuki Hirai, Eiji Kobayashi, Yosuke Nakanishi, Satoru Kondo, Tomokazu Yoshizaki
Publikováno v:
Thyroid Research, Vol 17, Iss 1, Pp 1-9 (2024)
Abstract Introduction Activation of the MAPK pathway by genetic mutations (such as BRAF and RET) initiates and accelerates the growth of papillary thyroid carcinoma (PTC). However, the correlation between genetic mutations and clinical features remai
Externí odkaz:
https://doaj.org/article/c9b65364cc504a00b68c1590d7d2b76e
Autor:
Otoya Kitaoka, Kohei Oyabu, Kaori Kubota, Takuya Watanabe, Satoru Kondo, Teppei Matsui, Shutaro Katsurabayashi, Katsunori Iwasaki
Publikováno v:
Frontiers in Neural Circuits, Vol 18 (2024)
A morphologically present but non-functioning synapse is termed a silent synapse. Silent synapses are categorized into “postsynaptically silent synapses,” where AMPA receptors are either absent or non-functional, and “presynaptically silent syn
Externí odkaz:
https://doaj.org/article/dc5db946906a45c0b05061ac54b5e146
Autor:
Harue Mizokami, Atsushi Okabe, Ruchi Choudhary, Masato Mima, Kenta Saeda, Masaki Fukuyo, Bahityar Rahmutulla, Motoaki Seki, Boon-Cher Goh, Satoru Kondo, Hirotomo Dochi, Makiko Moriyama-Kita, Kiyoshi Misawa, Toyoyuki Hanazawa, Patrick Tan, Tomokazu Yoshizaki, Melissa Jane Fullwood, Atsushi Kaneda
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105057- (2024)
Summary: Background: Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV)-associated malignant epithelial tumor endemic to Southern China and Southeast Asia. While previous studies have revealed a low frequency of gene mutations in NPC, its
Externí odkaz:
https://doaj.org/article/0d406c389ac048dea04ff8c3811564af
Autor:
Tomohiro Okagawa, Satoru Konnai, Shinya Goto, Yamato Sajiki, Otgontuya Ganbaatar, Kei Watari, Hayato Nakamura, Cai-Xia Wang, Taro Tachibana, Yukinari Kato, Yayoi Kameda, Junko Kohara, Nobuhiro Terasaki, Manabu Kubota, Akira Takeda, Hirofumi Takahashi, Yasuhiko Suzuki, Naoya Maekawa, Shiro Murata, Kazuhiko Ohashi
Publikováno v:
Veterinary Research, Vol 54, Iss 1, Pp 1-14 (2023)
Abstract Immune checkpoint molecules PD-1/PD-L1 cause T-cell exhaustion and contribute to disease progression in chronic infections of cattle. We established monoclonal antibodies (mAbs) that specifically inhibit the binding of bovine PD-1/PD-L1; how
Externí odkaz:
https://doaj.org/article/d1e0e81c1ed349c095a5bc6af2dd26e6
Autor:
Takahiko Omameuda, Mikio Shiozawa, Yuzo Miyahara, Hiroyuki Kitabayashi, Masaru Koizumi, Satoru Kondo, Shigeo Kawai, Masaaki Kodama
Publikováno v:
Surgical Case Reports, Vol 9, Iss 1, Pp 1-6 (2023)
Abstract Background Linea alba hernias are relatively rare types of hernias. They manifest as small protrusions situated in the linea alba between the umbilicus and xiphoid cartilage. Usually, hernia contents comprise the pre-peritoneal fat, omentum,
Externí odkaz:
https://doaj.org/article/8851b7e6dfaa40d2822a653f695a1316
Autor:
Bruno Moraes, Renato Martins, Cintia Lopes, Ronald Martins, Angélica Arcanjo, Jhenifer Nascimento, Satoru Konnai, Itabajara da Silva Vaz, Carlos Logullo
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
The enzyme glucose-6-phosphate dehydrogenase (G6PDH) plays crucial roles in glucose homeostasis and the pentose phosphate pathway (PPP), being also involved in redox metabolism. The PPP is an important metabolic pathway that produces ribose and nicot
Externí odkaz:
https://doaj.org/article/736884ce7fa342f484614b78fe30283d
Autor:
Shwe Yee Win, Hikari Seo, Fumiya Horio, Sotaro Fujisawa, Jumpei Sato, Yoshinosuke Motai, Takumi Sato, Eiji Oishi, Akira Taneno, Lat Lat Htun, Saw Bawm, Tomohiro Okagawa, Naoya Maekawa, Satoru Konnai, Kazuhiko Ohashi, Shiro Murata
Publikováno v:
Vaccines, Vol 12, Iss 2, p 148 (2024)
Poultry red mites (Dermanyssus gallinae, PRMs), tropical fowl mites (Ornithonyssus bursa, TFMs), and northern fowl mites (O. sylviarum, NFMs) are blood-feeding pests that debilitate poultry worldwide. Glutathione S-transferase (GST) plays an importan
Externí odkaz:
https://doaj.org/article/cb77113d2ef0450a9f50d657494ebbd9
Autor:
Yoshinosuke Motai, Shiro Murata, Jumpei Sato, Akihito Nishi, Naoya Maekawa, Tomohiro Okagawa, Satoru Konnai, Kazuhiko Ohashi
Publikováno v:
Veterinary Sciences, Vol 11, Iss 1, p 43 (2024)
Marek’s disease virus (MDV) causes malignant lymphoma (Marek’s disease; MD) in chickens. The Meq protein is essential for tumorigenesis since it regulates the expression of host and viral genes. Previously, we reported that the deletion of the sh
Externí odkaz:
https://doaj.org/article/207e8a781a2146a1b133c0b73bd98d6e
Autor:
Tomokazu Yoshizaki, Satoru Kondo, Hirotomo Dochi, Eiji Kobayashi, Harue Mizokami, Shigetaka Komura, Kazuhira Endo
Publikováno v:
Microorganisms, Vol 12, Iss 1, p 14 (2023)
Reports about the oncogenic mechanisms underlying nasopharyngeal carcinoma (NPC) have been accumulating since the discovery of Epstein-Barr virus (EBV) in NPC cells. EBV is the primary causative agent of NPC. EBV–host and tumor–immune system inte
Externí odkaz:
https://doaj.org/article/56538c0959ea4fd29c281fca7ca518ad
Autor:
Naoya Maekawa, Satoru Konnai, Yumie Asano, Yamato Sajiki, Tatsuya Deguchi, Tomohiro Okagawa, Kei Watari, Hiroto Takeuchi, Satoshi Takagi, Kenji Hosoya, Sangho Kim, Hiroshi Ohta, Yukinari Kato, Yasuhiko Suzuki, Shiro Murata, Kazuhiko Ohashi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Immune checkpoint inhibitors (ICIs) such as anti-PD-L1 antibodies are widely used to treat human cancers, and growing evidence suggests that ICIs are promising treatments for canine malignancies. However, only some canine oral malignant mela
Externí odkaz:
https://doaj.org/article/9195edeb9fe7415f92cb3f8d09b03d7b