Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Satoru Horiya"'
Autor:
Dung N. Nguyen, Bokai Xu, Robyn L. Stanfield, Jennifer K. Bailey, Satoru Horiya, J. Sebastian Temme, Deborah R. Leon, Celia C. LaBranche, David C. Montefiori, Catherine E. Costello, Ian A. Wilson, Isaac J. Krauss
Publikováno v:
ACS Central Science, Vol 5, Iss 2, Pp 237-249 (2019)
Externí odkaz:
https://doaj.org/article/9f4707366b53402dbecdc17a9b42eefa
Publikováno v:
ACS Infectious Diseases. 8:2232-2241
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fdd30f238b7df0918c86e2709ab4570
https://doi.org/10.1021/acsinfecdis.2c00442
https://doi.org/10.1021/acsinfecdis.2c00442
Autor:
Isaac J. Krauss, J. Sebastian Temme, Jennifer K. Bailey, Celia C. LaBranche, Satoru Horiya, Avital A. Rodal, ShiYu Wang, Dung N. Nguyen, Robyn L. Stanfield, Ian A. Wilson, David C. Montefiori, Bokai Xu, Richard L Redman
Publikováno v:
ACS Chemical Biology
The high mannose patch (HMP) of the HIV envelope protein (Env) is the structure most frequently targeted by broadly neutralizing antibodies; therefore, many researchers have attempted to use mimics of this region as a vaccine immunogen. In our previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308c71f5747e4e1f0d1535be78d70247
http://europepmc.org/articles/PMC7091532
http://europepmc.org/articles/PMC7091532
Publikováno v:
Tetrahedron. 72:6091-6098
Recently, we reported a directed evolution method which enabled us to discover sequences of glycopeptides that bind with picomolar affinity to HIV antibody 2G12 and are of interest as HIV vaccine candidates. In this manuscript, we describe the synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc65d2ad10fcf69ba13c9968d9f45cb9
https://doi.org/10.1016/j.tet.2016.07.062
https://doi.org/10.1016/j.tet.2016.07.062
Publikováno v:
Methods in enzymology. 597
Directed evolution is a useful method for the discovery of nucleic acids, peptides, or proteins that have desired binding abilities or functions. Because of the abundance and importance of glycosylation in nature, directed evolution of glycopeptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f6877aa1ceecf7069a39a477bd10c9
https://pubmed.ncbi.nlm.nih.gov/28935113
https://pubmed.ncbi.nlm.nih.gov/28935113
Publikováno v:
Nature Chemical Biology. 10:990-999
Although efforts to develop a vaccine against HIV have so far met with little success, recent studies of HIV-positive patients with strongly neutralizing sera have shown that the human immune system is capable of producing potent and broadly-neutrali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12fb647f6d979b7085137b0522902542
https://doi.org/10.1038/nchembio.1685
https://doi.org/10.1038/nchembio.1685
Autor:
Isaac J. Krauss, J. Sebastian Temme, Yollete V. Guillen Schlippe, Jennifer K. Bailey, Satoru Horiya
Publikováno v:
Journal of the American Chemical Society
Herein, we report a method for in vitro selection of multivalent glycopeptides, combining mRNA display with incorporation of unnatural amino acids and "click" chemistry. We have demonstrated the use of this method to design potential glycopeptide vac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b548d073df15618dc798e7bc30aa25
https://doi.org/10.1021/ja500678v
https://doi.org/10.1021/ja500678v
Autor:
Ryota Saito, Satoru Horiya, Kazuo Harada, Koh Kobayashi, Xianglan Li, Akira Katoh, Gota Kawai
Publikováno v:
Chemistry & Biology. 10(7):645-654
The high affinity and specificity of nucleic acid base complementarity has been proven to be a powerful method for constructing specific molecular assemblies. On the other hand, recent structural studies of RNA have revealed the wide range of tertiar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1740bd31253c8c285142678c64b15c3
Publikováno v:
RNA. 9:252-261
The arginine-rich domains of several RNA-binding proteins have been shown to bind their cognate RNAs with high affinities and specificities as isolated peptides, adopting different conformations within different complexes. The sequence simplicity and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8398209c7502924bf9c8415f101e7be9
https://doi.org/10.1261/rna.2152303
https://doi.org/10.1261/rna.2152303
Publikováno v:
Nucleic Acids Research
Many well-characterized examples of antisense RNAs from prokaryotic systems involve hybridization of the looped regions of stem-loop RNAs, presumably due to the high thermodynamic stability of the resulting loop-loop and loop-linear interactions. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f2fa0904f043e04ffc65fe62d18129
https://pubmed.ncbi.nlm.nih.gov/20156995
https://pubmed.ncbi.nlm.nih.gov/20156995