Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Satoru Harumiya"'
Autor:
Atsuko Yuki, Chifumi Fujii, Kazuhiro Yamanoi, Masatomo Kawakubo, Hisanori Matoba, Satoru Harumiya, Jun Nakayama
Publikováno v:
Cancer Science. 113:576-586
Biomarkers for early diagnosis of pancreatic cancer are greatly needed, as the high fatality of this cancer is in part due to delayed detection. α1,4-linked N-acetylglucosamine (αGlcNAc), a unique O-glycan specific to gastric gland mucus, is biosyn
Autor:
Chifumi Fujii, Satoru Harumiya, Yoshiko Sato, Masatomo Kawakubo, Hisanori Matoba, Jun Nakayama
Publikováno v:
Cancer science. 113(11)
Gastric cancer is the second leading cause of cancer deaths worldwide, and more understanding of its molecular basis is urgently needed. Gastric gland mucin secreted from pyloric gland cells, mucous neck cells, and cardiac gland cells of the gastric
Autor:
Nobuhiko Arisaka, Shigeru Kakuta, Kazuhiro Yamanoi, Hiroto Kawashima, Yoshiko Sato, Chifumi Fujii, Minoru Fukuda, Masaki Miyashita, Satoru Harumiya, Hitomi Komura, Yukinobu Goso, Masatomo Kawakubo, Jun Nakayama, Motohiro Okumura, Shigenori Yamada, Michiko N. Fukuda
Publikováno v:
Journal of Histochemistry & Cytochemistry. 67:759-770
Gastric adenocarcinoma cells secrete sulfomucins, but their role in gastric tumorigenesis remains unclear. To address that question, we generated A4gnt/ Chst4 double-knockout (DKO) mice by crossing A4gnt knockout (KO) mice, which spontaneously develo
Autor:
Masatomo, Kawakubo, Hitomi, Komura, Yukinobu, Goso, Motohiro, Okumura, Yoshiko, Sato, Chifumi, Fujii, Masaki, Miyashita, Nobuhiko, Arisaka, Satoru, Harumiya, Kazuhiro, Yamanoi, Shigenori, Yamada, Shigeru, Kakuta, Hiroto, Kawashima, Michiko N, Fukuda, Minoru, Fukuda, Jun, Nakayama
Publikováno v:
J Histochem Cytochem
Gastric adenocarcinoma cells secrete sulfomucins, but their role in gastric tumorigenesis remains unclear. To address that question, we generated A4gnt/Chst4 double-knockout (DKO) mice by crossing A4gnt knockout (KO) mice, which spontaneously develop
Autor:
Shingo Tajima, Minoru Akiyama, Yoshinori Miura, Hiroshi Wachi, Eita Fujimoto, Hiroo Kawano, Satoru Harumiya, Noriko Fujii, Koji Ono
Publikováno v:
Experimental Dermatology. 22:36-40
The precursor protein of localized cutaneous amyloidosis (LCA) is believed to be cytokeratins on the basis of previous immunohistochemical studies. To identify the candidate amyloid protein biochemically, amyloid proteins were extracted with distille
Autor:
Koji Ono, Satoru Harumiya, Shingo Tajima, Akira Kawada, Ryoji Nagai, Elastosis Yoshinaga, Hiroshi Wachi, Eita Fujimoto
Publikováno v:
Journal of Investigative Dermatology. 132:315-323
Accumulation of degenerated elastic fibers in the sun-exposed skin designated as actinic elastosis is a histological hallmark of photodamaged skin. Previous studies have indicated that the elastic fibers of actinic elastosis interact with lysozyme an
Autor:
Yasunori Kozutsumi, Manabu Fujimoto, Takahiro Adachi, Satoru Harumiya, Thomas F. Tedder, Matthias Wabl, Hiromu Takematsu
Publikováno v:
European Journal of Immunology. 42:241-247
CD22 (Siglec-2) is a B-cell membrane-bound lectin that recognizes glycan ligands containing α2,6-linked sialic acid (α2,6Sia) and negatively regulates signaling through the B-cell Ag receptor (BCR). Although CD22 has been investigated extensively,
Autor:
Ken'ichi Isobe, Jun Nakayama, Hiroyuki Kato, Mana Fukushima, Takashige Momose, Yasuo Yoshimura, Satoru Harumiya, Munehisa Kito
Publikováno v:
Human pathology. 50
The glycosyltransferases chondroitin sulfate synthase 1 (CHSY1) and exostoses-like 3 (EXTL3) specifically function in biosynthesis of the glycans chondroitin sulfate and heparan sulfate, respectively. Although these glycans play important roles in pa
Autor:
Daisaburo Fujimoto, Hitoshi Nagata, Satoru Harumiya, Noboru Saito, Koichi Soyama, Tatsuhiro Hayashi, Chiaki Narumo, Maki Mitsuhashi, Shingo Kameoka
Publikováno v:
International Journal of Clinical Oncology. 6:215-220
Background. To prevent tumor metastasis, we administered the cell-binding domain of fibronectin, in combination with the angiogenesis inhibitor TNP-470, to mice with hepatic metastasis. We then assessed the prevention of tumor metastasis resulting fr
Autor:
Kazumi Yagasaki, Yoshikazu Fujimori, Daisaburo Fujimoto, Yutaka Miura, Satoru Harumiya, Hiroyuki Tachikawa, Yuki Fukumoto
Publikováno v:
Biochemical and Biophysical Research Communications. 244:796-800
A novel ficolin-related gene was isolated from the mouse liver lambda ZAPII cDNA library. The protein encoded by this gene consists of both collagen- and fibrinogen-like domains, which are common features of the ficolin family, and was named mouse fi