Výsledky vyhledávání - "Satoru, Matsumoto"

Akademický článek

Baseline Nutritional Status and Rehabilitation Progress in Individuals Requiring Inpatient Rehabilitation: A Retrospective Cohort Study

Autor: Hideki Arai, MD, PhD, Syuya Okada, PT, Tatsuyuki Fukuoka, SLP, PhD, Masafumi Nozoe, PT, PhD, Kuniyasu Kamiya, PT, PhD, Satoru Matsumoto, MD

Publikováno v: Archives of Rehabilitation Research and Clinical Translation, Vol 6, Iss 3, Pp 100362- (2024)

Objective: To evaluate the relationships between baseline nutritional status, medical events (MEs), and rehabilitation outcomes in individuals undergoing inpatient rehabilitation (IR). Design: A retrospective single center cohort study. Setting: An I

Externí odkaz: https://doaj.org/article/cc74e580c73240db97b027daaab597c4

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Akademický článek

HLA class II neoantigen presentation for CD4+ T cell surveillance in HLA class II-negative colorectal cancer

Autor: Satoru Matsumoto, Takahiro Tsujikawa, Serina Tokita, Mai Mohamed Bedeir, Kazuhiko Matsuo, Fumitake Hata, Yoshihiko Hirohashi, Takayuki Kanaseki, Toshihiko Torigoe

Publikováno v: OncoImmunology, Vol 13, Iss 1 (2024)

Neoantigen-reactive CD4+ T cells play a key role in the anti-tumor immune response. However, the majority of epithelial tumors are negative for HLA class II (HLA-II) surface expression, and less is known about the processing of HLA-II antigens. Here,

Externí odkaz: https://doaj.org/article/48ffcd9f1ce14d8b88fdb93819995a7b

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Akademický článek

Association of Baseline Skeletal Muscle Mass Index With Adverse Events and Rehabilitation Outcomes in Patients Admitted for Rehabilitation

Autor: Hideki Arai, MD, Syuya Okada, PT, Tatsuyuki Fukuoka, SLP, PhD, Masafumi Nozoe, PT, PhD, Kuniyasu Kamiya, PT, PhD, Satoru Matsumoto, MD, Takeshi Morimoto, MD, PhD MPH

Publikováno v: Archives of Rehabilitation Research and Clinical Translation, Vol 6, Iss 1, Pp 100314- (2024)

Objective: To assess the associations of baseline skeletal muscle mass index (SMI) with adverse events and rehabilitation outcomes in patients admitted for rehabilitation. Design: A retrospective cohort study. Participants: The subjects were 409 pati

Externí odkaz: https://doaj.org/article/2a4f310f2da94127afc4469ae4999407

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Akademický článek

Low immunogenicity of LNP allows repeated administrations of CRISPR-Cas9 mRNA into skeletal muscle in mice

Autor: Eriya Kenjo, Hiroyuki Hozumi, Yukimasa Makita, Kumiko A. Iwabuchi, Naoko Fujimoto, Satoru Matsumoto, Maya Kimura, Yuichiro Amano, Masataka Ifuku, Youichi Naoe, Naoto Inukai, Akitsu Hotta

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)

In vivo delivery of CRISPR-Cas9 holds promise for treating muscular dystrophy, however, AAV delivery is known to be immunogenic. Here, the authors show that LNP delivery of CRISPR-Cas9 enables repeated injections into skeletal muscle and leads to res

Externí odkaz: https://doaj.org/article/82ba1424688643b8923145dd7be8e610

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Akademický článek

In Vitro Antibacterial Activity of Imipenem/Relebactam against Clinical Isolates in Japan

Autor: Dai Kurihara, Satoru Matsumoto, Naoko Kishi, Yoshikazu Ishii, Masahiko Mori

Publikováno v: Microbiology Spectrum, Vol 10, Iss 2 (2022)

ABSTRACT Relebactam is a novel β-lactamase inhibitor of Ambler class A and C β-lactamases that has been developed in combination with imipenem/cilastatin for the treatment of carbapenem-resistant bacterial infections. In this study, we evaluated th

Externí odkaz: https://doaj.org/article/285be98a95104f62a71b6a64f7216ff1

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Supplementary Table 2, 3, and Figures from LSD1 Inhibitor T-3775440 Inhibits SCLC Cell Proliferation by Disrupting LSD1 Interactions with SNAG Domain Proteins INSM1 and GFI1B

Autor: Kazuhide Nakamura, Toshiyuki Nomura, Yusuke Kamada, Satoru Matsumoto, Shinji Iwasaki, Akio Mizutani, Yoshinori Ishikawa, Shinji Takagi

Supplementary Table 2: Genes commonly up-regulated or down-regulated by T-3775440 treatment in NCI-H1417, NCI-H510A, and NCI-526 cells. Supplementary Table 3: Plasma concentration and pharmacokinetic properties of T-3775440 in mice treated with a sin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59aa0a4056e207801f097555a1fc50ee
https://doi.org/10.1158/0008-5472.22415366

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Data from LSD1 Inhibitor T-3775440 Inhibits SCLC Cell Proliferation by Disrupting LSD1 Interactions with SNAG Domain Proteins INSM1 and GFI1B

Autor: Kazuhide Nakamura, Toshiyuki Nomura, Yusuke Kamada, Satoru Matsumoto, Shinji Iwasaki, Akio Mizutani, Yoshinori Ishikawa, Shinji Takagi

T-3775440 is an irreversible inhibitor of the chromatin demethylase LSD1, which exerts antiproliferative effects by disrupting the interaction between LSD1 and GFI1B, a SNAG domain transcription factor, inducing leukemia cell transdifferentiation. He

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90a111c5411d840d2bd99bea697fc178
https://doi.org/10.1158/0008-5472.c.6509255.v1

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Akademický článek

Association Between Skeletal Muscle Mass Index and Falls in Patients With Functional Impairment.

Autor: Hideki Arai, Masafumi Nozoe, Kuniyasu Kamiya, Satoru Matsumoto, Takeshi Morimoto

Publikováno v: American Journal of Physical Medicine & Rehabilitation; Oct2023, Vol. 102 Issue 10, p913-918, 6p

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