Výsledky vyhledávání - "Satomi Urano"

Akademický článek

Mechanism of intramembrane cleavage of alcadeins by γ-secretase.

Autor: Yi Piao, Ayano Kimura, Satomi Urano, Yuhki Saito, Hidenori Taru, Tohru Yamamoto, Saori Hata, Toshiharu Suzuki

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e62431 (2013)

BackgroundAlcadein proteins (Alcs; Alcα, Alcβand Alcγ) are predominantly expressed in neurons, as is Alzheimer's β-amyloid (Aβ) precursor protein (APP). Both Alcs and APP are cleaved by primary α- or β-secretase to generate membrane-associated

Externí odkaz: https://doaj.org/article/d837907de24f4ed784ec9c3f5f58eae3

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Cytoplasmic Fragment of Alcadein α Generated by Regulated Intramembrane Proteolysis Enhances Amyloid β-Protein Precursor (APP) Transport into the Late Secretory Pathway and Facilitates APP Cleavage

Autor: Satomi Urano, Saori Hata, Toshiharu Suzuki, Tadashi Nakaya, Yi Piao, Hidenori Taru, Yuriko Sobu, Yoichi Araki, Ayano Kimura, Norio Takei, Tohru Yamamoto

Publikováno v: Journal of Biological Chemistry. 290:987-995

The neural type I membrane protein Alcadein α (Alcα), is primarily cleaved by amyloid β-protein precursor (APP) α-secretase to generate a membrane-associated carboxyl-terminal fragment (Alcα CTF), which is further cleaved by γ-secretase to secr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f8db8e5560310537725d68d11ec590b
https://doi.org/10.1074/jbc.m114.599852

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Mechanism of Intramembrane Cleavage of Alcadeins by γ-Secretase

Autor: Ayano Kimura, Saori Hata, Satomi Urano, Toshiharu Suzuki, Yuhki Saito, Tohru Yamamoto, Yi Piao, Hidenori Taru

Publikováno v: PLoS ONE
PLoS ONE, Vol 8, Iss 4, p e62431 (2013)

Background: Alcadein proteins (Alcs; Alc alpha, Alc beta and Alc gamma) are predominantly expressed in neurons, as is Alzheimer's beta-amyloid (A beta) precursor protein (APP). Both Alcs and APP are cleaved by primary alpha-or beta-secretase to gener

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bda57c2fc908932ac9f2e549c55769b
http://europepmc.org/articles/PMC3637299

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P1‐391: Intracellular dynamics of Alcadein family molecules and their metabolites in neuronal cells and tissues

Autor: Tadashi Nakaya, Tohru Yamamoto, Satomi Urano, Toshiharu Suzuki, Naoya Gotoh, Chiaki Maruta

Publikováno v: Alzheimer's & Dementia. 4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e1b5edb55cb34c7ef355d9cc687da5b9
https://doi.org/10.1016/j.jalz.2008.05.972

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Transport of APP and Alcadein by kinesin‐1

Autor: Tadashi Nakaya, Takahiro Arakawa, Masataka Kinjyo, Tomoko Kawai, Yoichi Araki, Toshiharu Suzuki, Tohru Yamamoto, Takanori Kawano, Takahide Matsushima, Satomi Urano, Mayu Akiyama

Publikováno v: The FASEB Journal. 21

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7706186bd64fe989a53098cec239fc94
https://doi.org/10.1096/fasebj.21.6.lb35-c

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Akademický článek

Cytoplasmic Fragment of Alcadein α Generated by Regulated Intramembrane Proteolysis Enhances Amyloid β-Protein Precursor (APP) Transport into the Late Secretory Pathway and Facilitates APP Cleavage.

Autor: Norio Takei¹, Yuriko Sobu¹, Ayano Kimura¹, Satomi Urano¹, Yi Piao¹, Yoichi Araki¹, Hidenori Taru¹, Tohru Yamamoto², Saori Hata¹, Tadashi Nakaya¹, Toshiharu Suzuki¹ tsuzuki@pharm.hokudai.ac.jp

Publikováno v: Journal of Biological Chemistry. 1/9/2015, Vol. 290 Issue 2, p987-995. 9p.

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