Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Satomi Nadanaka"'
Autor:
Akihiro Harada, Masataka Kunii, Kazuo Kurokawa, Takuya Sumi, Satoshi Kanda, Yu Zhang, Satomi Nadanaka, Koichiro M. Hirosawa, Kazuaki Tokunaga, Takuro Tojima, Manabu Taniguchi, Kenta Moriwaki, Shin-ichiro Yoshimura, Miki Yamamoto-Hino, Satoshi Goto, Toyomasa Katagiri, Satoshi Kume, Mitsuko Hayashi-Nishino, Miyako Nakano, Eiji Miyoshi, Kenichi G. N. Suzuki, Hiroshi Kitagawa, Akihiko Nakano
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Knowledge on the distribution and dynamics of glycosylation enzymes in the Golgi is essential for better understanding this modification. Here, using a combination of CRISPR/Cas9 knockin technology and super-resolution microscopy, we show th
Externí odkaz:
https://doaj.org/article/fd8fce91b1f74602a6b152cacc39ff8a
Autor:
Muneaki Matsuo, Satomi Nadanaka, Minami Soga, Taku Sugiyama, Shota Serigano, Kenjiro Shimano, Fumio Ichinose, Takuji Nakamura, Toshiyuki Maeda, Kiyohiro Houkin, Takumi Era, Hiroshi Kitagawa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Moyamoya disease (MMD) is characterized by progressive bilateral stenotic changes in the terminal portion of the internal carotid arteries. Although RNF213 was identified as a susceptibility gene for MMD, the exact pathogenesis remains unkno
Externí odkaz:
https://doaj.org/article/4931d18d48794dc3b194c282c4d9dd64
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Kitazawa et al. show that chondroitin 6-sulfate represses keratinocyte proliferation in skin. They find that mice deficient in chondroitin-6-O-sulfotransferase-1 (C6st-1), which synthesizes chondroitin 6-sulfate, exhibit keratinocyte hyperproliferati
Externí odkaz:
https://doaj.org/article/f5ee692e9c0645bdbe1c36a9b082fc46
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Extracellular and cell surface chondroitin sulfates (CSs) regulate cancer cell properties, including proliferation and invasion. Thus, it is necessary to understand the mechanisms underlying their roles in cancer. Although we have shown that CS has a
Externí odkaz:
https://doaj.org/article/b9440f026ec346f6ae021677db552682
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Basal-like breast cancer is characterized by an aggressive clinical outcome and presence of metastasis, for which effective therapies are unavailable. We have previously shown that chondroitin 4-O-sulfotransferase-1 (C4ST-1) controls the invasive pro
Externí odkaz:
https://doaj.org/article/e948b923237b4f7da2aec89c739f5f89
Autor:
Satomi Nadanaka, Shinji Miyata, Bai Yaqiang, Jun-ichi Tamura, Osami Habuchi, Hiroshi Kitagawa
Publikováno v:
Biomolecules, Vol 10, Iss 11, p 1499 (2020)
The chondroitin sulfate (CS)-rich dense extracellular matrix surrounding neuron cell bodies and proximal dendrites in a mesh-like structure is called a perineuronal net (PNN). CS chains in PNNs control neuronal plasticity by binding to PNN effectors,
Externí odkaz:
https://doaj.org/article/da7c69a4e8cb42a59937f42c14ae68af
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 12 (2018)
Aggrecan, a chondroitin sulfate (CS) proteoglycan, forms lattice-like extracellular matrix structures called perineuronal nets (PNNs). Neocortical PNNs primarily ensheath parvalbumin-expressing inhibitory neurons (parvalbumin, PV cells) late in brain
Externí odkaz:
https://doaj.org/article/130a41dde64a494e956470ce45035956
Autor:
Masafumi Tanaka, Toru Takarada, Satomi Nadanaka, Risa Kojima, Kimiko Hosoi, Yuki Machiba, Hiroshi Kitagawa, Toshiyuki Yamada
Publikováno v:
Archives of Biochemistry and Biophysics. 742:109615
Publikováno v:
British journal of pharmacologyREFERENCES. 179(20)
Chondroitin sulfate proteoglycan (CSPG) constitutes the neurogenic niche in the hippocampus. The reduction of hippocampal neurogenesis is involved in ageing-related cognitive decline and dementia. The purpose of this study is to find candidates that
Autor:
Okiko Miyata, Imam Manggalya Adhikara, Naoto Sasaki, Hiroshi Kitagawa, Gusty Rizky Teguh Ryanto, Yoshiyuki Rikitake, Noriaki Emoto, Michihiro Igarashi, Dyah Samti Mayasari, Koji Ikeda, Yoko Suzuki, Satomi Nadanaka, Ken-ichi Hirata, Keiko Yagi
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41:1076-1091
Objective: Chondroitin sulfate proteoglycans are the primary constituents of the macrophage glycosaminoglycan and extracellular microenvironment. To examine their potential role in atherogenesis, we investigated the biological importance of one of th