Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Satomi Maeba"'
Autor:
Yoshimitsu Abiko, Masafumi Yamamoto, Mitsuo Hayakawa, Satomi Maeba, Shigeo Otake, Jun Namikoshi
Publikováno v:
International Journal of Oral-Medical Sciences. 3:67-74
Porphyromonus gingivalis is a major pathogen of chronic periodontitis. An outer membrane protein with a molecular mass of 40-kDa (40k-OMP) is a highly immunogenic surface protein produced by P. gingivalis. In this study, to develop an effective vacci
Publikováno v:
International Journal of Oral-Medical Sciences. 3:34-40
Transcutaneous immunization is a new method of vaccination that utilizes a topical application of antigen to intact skin for induction of immune responses. In this study, we have assessed the potential for the application of transcutaneous immunizati
Autor:
Hirotsugu Yamamoto, Masahiko Fukumoto, Emilio A. Campos, Masafumi Yamamoto, Satomi Maeba, Jun Namikoshi
Publikováno v:
Journal of Oral Science. 45:25-31
It is well established that cholera toxin (CT) produced by Vibrio cholerae acts as a potent mucosal adjuvant; however, the native form of this molecule causes severe diarrhea. Furthermore, both native CT and its B-subunit derivative bind to monosialo
Autor:
Mitsuo Hayakawa, Yoshimitsu Abiko, Masafumi Yamamoto, Satomi Maeba, Shigeo Otake, Jun Namikoshi
Publikováno v:
International Journal of Oral-Medical Sciences. 1:90-96
It is well established that Porphyromonas gingivalis is one of the major pathogens of adult periodontitis. P. gingivalis produces an outer membrane protein with a molecular mass of 40-kDa (40k-OMP). In the present study, in order to assess the potent
Autor:
Yasuko Shibata, Mitsuo Hayakawa, Yoshimitsu Abiko, Masafumi Yamamoto, Satomi Maeba, Jun Namikoshi, Shigeo Otake
Publikováno v:
Vaccine. 23(19)
This study seeks to assess the potential of a 40-kDa outer membrane protein of Porphyromonas gingivalis (40k-OMP) as a transcutaneous vaccine against chronic periodontitis. Transcutaneous immunization (TCI) of mice with 40k-OMP alone elicited 40k-OMP
Autor:
Shigeo Otake, Masafumi Yamamoto, Satomi Maeba, Mitsuo Hayakawa, Jun Namikoshi, Yoshimitsu Abiko
Publikováno v:
Vaccine. 22(2)
In this study, we have assessed the efficacy of the 40-kDa outer membrane protein (40k-OMP) of Porphyromonas gingivalis as a nasal vaccine for the prevention of adult periodontitis. Mice nasally immunized with 40k-OMP and cholera toxin as mucosal adj