Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Satomi Adachi-Akahane"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 153, Iss 3, Pp 130-141 (2023)
Diabetes mellitus is a prevalent risk factor for congestive heart failure. Diabetic cardiomyopathy patients present with left ventricular (LV) diastolic dysfunction at an early stage, then systolic dysfunction as the disease progresses. The mechanism
Externí odkaz:
https://doaj.org/article/779ad662343d45e9bfd73c537184376e
Autor:
Takashi Nishina, Yutaka Deguchi, Daisuke Ohshima, Wakami Takeda, Masato Ohtsuka, Shigeyuki Shichino, Satoshi Ueha, Soh Yamazaki, Mika Kawauchi, Eri Nakamura, Chiharu Nishiyama, Yuko Kojima, Satomi Adachi-Akahane, Mizuho Hasegawa, Mizuho Nakayama, Masanobu Oshima, Hideo Yagita, Kazutoshi Shibuya, Tetuo Mikami, Naohiro Inohara, Kouji Matsushima, Norihiro Tada, Hiroyasu Nakano
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The stromal fibroblast population in the colon is composed of heterogeneous and distinct cell subtypes that play a crucial role in the development of colitis and colon cancer. Here the authors generate IL-11 reporter mice and characterize the origin
Externí odkaz:
https://doaj.org/article/3db3ac661ebb40e88567f28d3824a2f8
Autor:
Shin Murai, Yoshifumi Yamaguchi, Yoshitaka Shirasaki, Mai Yamagishi, Ryodai Shindo, Joanne M. Hildebrand, Ryosuke Miura, Osamu Nakabayashi, Mamoru Totsuka, Taichiro Tomida, Satomi Adachi-Akahane, Sotaro Uemura, John Silke, Hideo Yagita, Masayuki Miura, Hiroyasu Nakano
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Necroptotic cells activate MLKL and release inflammatory DAMPs, although the underlying regulatory mechanisms of this process are poorly understood. Here, Murai et al. develop a necroptosis-specific FRET sensor (SMART) that monitors MLKL membrane tra
Externí odkaz:
https://doaj.org/article/dd6ff8d68eec4a60838196219a4980cf
Autor:
Satomi Adachi-Akahane, Yukio Hiroi, Hiromasa Hayama, Masao Moroi, Tokuhisa Uejima, Hisao Hara
Publikováno v:
Circulation Journal. 86:947-955
Several non-invasive methods for pulmonary vascular resistance (PVR) measurement are proposed, but none are sufficiently accurate for use in clinical practice. This study proposes a new echocardiographic method of pulmonary artery wave reflection and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30117c0fa05dd8b22f3e3ba19d766987
https://doi.org/10.1253/circj.cj-21-0646
https://doi.org/10.1253/circj.cj-21-0646
Autor:
Shin Murai, Yoshifumi Yamaguchi, Yoshitaka Shirasaki, Mai Yamagishi, Ryodai Shindo, Joanne M. Hildebrand, Ryosuke Miura, Osamu Nakabayashi, Mamoru Totsuka, Taichiro Tomida, Satomi Adachi-Akahane, Sotaro Uemura, John Silke, Hideo Yagita, Masayuki Miura, Hiroyasu Nakano
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-2 (2019)
The cDNA sequence of human SMART described in this Article was misreported, as described in the accompanying Addendum. This error does not affect the results or any conclusion of the Article.
Externí odkaz:
https://doaj.org/article/6ec060a9b0804eb8a5d9ec4b287b8fcf
Autor:
Yasuhiko Nakamura, Naohisa Urabe, Susumu Sakamoto, Kazutoshi Isobe, Yujiro Takai, Akira Iyoda, Muneyuki Sekiya, Takahiro Yoshizawa, Takuma Isshiki, Sakae Homma, Shion Miyoshi, Taichiro Tomida, Kazuma Kishi, Satomi Adachi-Akahane
Publikováno v:
Respiratory Investigation. 59:535-544
Background The response rate for osimertinib is high among patients with untreated epidermal growth factor receptor (EGFR) mutation-positive non-small cell lung cancer (NSCLC). However, there exist no biomarkers to predict the efficacy of the same. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad33e4a3d8f4eb051a837543c73bd73
https://doi.org/10.1016/j.resinv.2021.03.010
https://doi.org/10.1016/j.resinv.2021.03.010
Autor:
Masanori Ito, Satomi Adachi-Akahane
Publikováno v:
Journal of Pharmacological Sciences, Vol 123, Iss 4, Pp 312-317 (2013)
Recent studies have shown that lipid metabolism is regulated through the orchestration of multiple organs. Gut microbiota influences the metabolism of the liver through the production of fatty acids and phosphatidylcholine as well as the modulation o
Externí odkaz:
https://doaj.org/article/38076be9c80c4501abf68a87bef3f9d0
Autor:
Taichiro Tomida, Satomi Adachi-Akahane
Publikováno v:
Folia Pharmacologica Japonica. 155:241-247
Sarcopenia and frailty in aging, or cancer cachexia shows an abnormal decrease in skeletal muscle mass and muscle strength. However, the underlying mechanisms are not clear, and the promising drug seeds have not been discovered. The formation of skel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d5b11b5b4b37685753fdf69b4d4676
https://doi.org/10.1254/fpj20030
https://doi.org/10.1254/fpj20030
Autor:
Satomi Adachi-Akahane
Publikováno v:
Folia Pharmacologica Japonica. 158:164-164
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a4ac0c8c4c30f99c412c3b2c34eb08b
https://doi.org/10.1254/fpj.22162
https://doi.org/10.1254/fpj.22162
Autor:
Shin-ichi Morimoto, Masanori Ito, Satoko Oda, Atsushi Sugiyama, Masaru Kuroda, Satomi Adachi-Akahane
Publikováno v:
Journal of Pharmacological Sciences, Vol 118, Iss 4, Pp 455-466 (2012)
We studied the antiallodynic effect of gabapentin (GBP) in the mouse model of neuropathic pain, aiming at clarifying the underlying mechanism. The L5 spinal nerve ligation induced tactile allodynia, an increase of CD11b expression, and an increase in
Externí odkaz:
https://doaj.org/article/5d3499dcf1f2498cabc48bc5b5c38a63