Zobrazeno 1 - 10
of 256
pro vyhledávání: '"Satomi, Onoue"'
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2708 (2023)
Oral administration of active pharmaceutical ingredients is desirable because it is easy, safe, painless, and can be performed by patients, resulting in good medication adherence. The mucus layer in the gastrointestinal (GI) tract generally acts as a
Externí odkaz:
https://doaj.org/article/8c3354b42eaa4cbe80f4ffbb662ada52
Publikováno v:
Health Science Reports, Vol 6, Iss 4, Pp n/a-n/a (2023)
Abstract Background and Aims Burning mouth syndrome (BMS) causes burning or uncomfortable feelings in the oral cavity without any obvious injuries. This condition's etiopathogenesis is still unknown, consequently, BMS management is very challenging.
Externí odkaz:
https://doaj.org/article/16be137a9bd64ef28a87f67dc1dcffaa
Autor:
Antara Ghosh, Sujan Banik, Kohei Yamada, Shingen Misaka, Robert K. Prud’homme, Hideyuki Sato, Satomi Onoue
Publikováno v:
Pharmaceutics, Vol 15, Iss 11, p 2562 (2023)
In this study, we developed stabilized astaxanthin (AX) nanoparticles (sNP/AX) to improve the physicochemical properties, oral bioavailability, and hepatoprotection of AX. A flash nanoprecipitation technique was used with a multi-inlet vortex mixer t
Externí odkaz:
https://doaj.org/article/a68a3017fff74b568e503ac73f460b06
Publikováno v:
Journal of Pharmacological Sciences, Vol 148, Iss 1, Pp 51-55 (2022)
The present study aimed to characterize and compare β-adrenoceptors in the rat bladder with those in the heart and lungs of SD rats (8–10 weeks old) using subtype-selective agonists and antagonists in a radioligand binding assay with (-)-[125I]cya
Externí odkaz:
https://doaj.org/article/8124cac8bdc44de7a6842245cb92373e
Autor:
Koji Higuchi, Kohei Yamada, Tsubasa Kihara, Keisuke Makino, Kenta Sasaki, Takeshi Shindo, Hiroshi Shikama, Hideyuki Sato, Satomi Onoue
Publikováno v:
Molecules, Vol 28, Iss 14, p 5325 (2023)
The aim of the present study was to develop an injectable hydrogel (HG) formulation of fuzapladib sodium (FZP), an animal drug for acute pancreatitis (AP), with the use of polyethyleneoxide (PEO) and polylysine (pLys), a cationic polymer. A mixture o
Externí odkaz:
https://doaj.org/article/483febe869ca424a81771266ef2d7e65
Autor:
Shingen Misaka, Yuko Ono, Atsushi Uchida, Tomoyuki Ono, Osamu Abe, Hiroshi Ogata, Hideyuki Sato, Masahiko Suzuki, Satomi Onoue, Yayoi Shikama, Kenju Shimomura
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 2, Pp 476-480 (2021)
Lisinopril, a highly hydrophilic long‐acting angiotensin‐converting enzyme inhibitor, is frequently prescribed for the treatment of hypertension and congestive heart failure. Green tea consumption may reduce the risk of cardiovascular outcomes an
Externí odkaz:
https://doaj.org/article/8ffee0fc0dfb4bab84c1da2a2c3ecaa5
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 571 (2023)
This study aimed to develop a cyclosporine A (CsA)-loaded ternary solid dispersion (tSD/CsA) to improve the storage stability of a solid dispersion (SD) system and the oral absorbability of CsA. Hydroxypropyl cellulose (HPC) and hydroxypropyl methylc
Externí odkaz:
https://doaj.org/article/734d7f0aff0a4d9a96fa8dcc5e162e3f
Autor:
Shizuo Yamada, Shiori Kuraoka, Yoshihiko Ito, Satomi Kagota, Kazumasa Shinozuka, Satomi Onoue
Publikováno v:
Journal of Pharmacological Sciences, Vol 142, Iss 3, Pp 127-130 (2020)
In vitro and in vivo binding sites of [3H]-labeled 5-hydroxymethyltolterodine (5-HMT), a new radioligand for labeling muscarinic receptors in rat tissues were characterized. Specific [3H]5-HMT binding in rat tissues was saturable and of high affinity
Externí odkaz:
https://doaj.org/article/8d01d0ded5f342f3b6586d81af768f49
Autor:
Hideyuki Sato, Aiko Tabata, Tatsuru Moritani, Tadahiko Morinaga, Takahiro Mizumoto, Yoshiki Seto, Satomi Onoue
Publikováno v:
Molecules, Vol 27, Iss 20, p 6775 (2022)
The author wishes to make the following correction to this paper [...]
Externí odkaz:
https://doaj.org/article/5d0bc2cbf2a04639b5940aac6e32e0b0
Publikováno v:
Journal of Pharmacological Sciences, Vol 140, Iss 1, Pp 73-78 (2019)
The present study aimed to characterize muscarinic receptor binding of fesoterodine, 5-hydroxymethyl tolterodine (5-HMT), and tolterodine in bladder and other tissues of rats after their oral, intravenous, or intravesical administration. Muscarinic r
Externí odkaz:
https://doaj.org/article/e423b64aa554465e82b26cff8f424fe7