Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Satish Kalari"'
Autor:
Satish Kalari, Nagabhushan Moolky, Srikanth Pendyala, Evgeny V Berdyshev, Cleo Rolle, Rajani Kanteti, Archana Kanteti, Wenli Ma, Donghong He, Aliya N Husain, Hedy L Kindler, Prasad Kanteti, Ravi Salgia, Viswanathan Natarajan
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45330 (2012)
Malignant pleural mesothelioma (MPM) is a devastating disease with an overall poor prognosis. Despite the recent advances in targeted molecular therapies, there is a clear and urgent need for the identification of novel mesothelioma targets for the d
Externí odkaz:
https://doaj.org/article/cceb3ea0c27c4fb0bf82c7b82837b92b
Autor:
Evgeny V Berdyshev, Irina Gorshkova, Peter Usatyuk, Satish Kalari, Yutong Zhao, Nigel J Pyne, Susan Pyne, Roger A Sabbadini, Joe G N Garcia, Viswanathan Natarajan
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16571 (2011)
Earlier we have shown that extracellular sphingosine-1-phosphate (S1P) induces migration of human pulmonary artery endothelial cells (HPAECs) through the activation of S1P(1) receptor, PKCε, and PLD2-PKCζ-Rac1 signaling cascade. As endothelial cell
Externí odkaz:
https://doaj.org/article/cc99e3f2d99b49cfbd0f1ee6c9092044
Autor:
Viswanathan Natarajan, Satish Kalari, Steven R. Kleeberger, Yutong Zhao, Srikanth Pendyala, Joe G.N. Garcia, Jaideep Moitra, Sekhar P. Reddy
Publikováno v:
Free Radical Biology and Medicine. 50:1749-1759
Reactive oxygen species (ROS) generated by vascular endothelial and smooth muscle cells contribute to the development and progression of vascular diseases. We have recently shown that hyperoxia enhances NADPH oxidase 4 (Nox4) expression, which regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094f473fa87782a4e43b8a227561d75c
https://doi.org/10.1016/j.freeradbiomed.2011.03.022
https://doi.org/10.1016/j.freeradbiomed.2011.03.022
Autor:
Peter V. Usatyuk, Viswanathan Natarajan, Yutong Zhao, Donghong He, Satish Kalari, Joe G.N. Garcia, Irina Gorshkova
Publikováno v:
Journal of Biological Chemistry. 284:15339-15352
Phosphatidic acid generated by the activation of phospholipase D (PLD) functions as a second messenger and plays a vital role in cell signaling. Here we demonstrate that PLD-dependent generation of phosphatidic acid is critical for Rac1/IQGAP1 signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef926be28d23a2ed301c7b3bd91d0938
https://doi.org/10.1074/jbc.m109.005439
https://doi.org/10.1074/jbc.m109.005439
Autor:
Peter V. Usatyuk, Tonya Watkins, Donghong He, Yutong Zhao, Viswanathan Natarajan, Evgeni V. Berdyshev, Chaode Sun, Irina Gorshkova, Robert Bittman, David N. Brindley, Joe G.N. Garcia, Satish Kalari
Publikováno v:
Journal of Biological Chemistry. 282:14165-14177
Sphingosine 1-phosphate (S1P) regulates diverse cellular functions through extracellular ligation to S1P receptors, and it also functions as an intracellular second messenger. Human pulmonary artery endothelial cells (HPAECs) effectively utilized exo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad858d4bd31bb9814998af6ce03abc83
https://doi.org/10.1074/jbc.m701279200
https://doi.org/10.1074/jbc.m701279200
Autor:
Jaideep Moitra, Srikanth Pendyala, Donghong He, Joe G.N. Garcia, Satish Kalari, Peter V. Usatyuk, Viswanathan Natarajan, Sara M. Camp, Patrick A. Singleton, Steven M. Dudek, Irina Gorshkova
Publikováno v:
The Journal of biological chemistry. 287(12)
We recently demonstrated that hyperoxia (HO) activates lung endothelial cell NADPH oxidase and generates reactive oxygen species (ROS)/superoxide via Src-dependent tyrosine phosphorylation of p47(phox) and cortactin. Here, we demonstrate that the non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d2dd1819adf2c3302ce5a7c61f54b3f
https://pubmed.ncbi.nlm.nih.gov/22219181
https://pubmed.ncbi.nlm.nih.gov/22219181
Autor:
Cleo E. Rolle, Srikanth Pendyala, Viswanathan Natarajan, Ravi Salgia, Donghong He, Archana Kanteti, Rajani Kanteti, Aliya N. Husain, Prasad Kanteti, Nagabhushan Moolky, Satish Kalari, Hedy L. Kindler, Evgeny V. Berdyshev, Wenli Ma
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45330 (2012)
PLoS ONE
PLoS ONE
Background Malignant pleural mesothelioma (MPM) is a devastating disease with an overall poor prognosis. Despite the recent advances in targeted molecular therapies, there is a clear and urgent need for the identification of novel mesothelioma target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596bcc64c0cef303c388ef529aff943e
http://europepmc.org/articles/PMC3444486?pdf=render
http://europepmc.org/articles/PMC3444486?pdf=render
Publikováno v:
Oncogene. 32(30)
Small cell lung cancer (SCLC) is a disease characterized by aggressive clinical behavior and lack of effective therapy. Due to its tendency for early dissemination, only a third of patients have limited-stage disease at the time of diagnosis. SCLC is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c3e494641ddb5a2a0656be2c03e414
https://pubmed.ncbi.nlm.nih.gov/22907430
https://pubmed.ncbi.nlm.nih.gov/22907430
Publikováno v:
C66. MOLECULAR TARGETS FOR THERAPEUTIC DEVELOPMENT IN LUNG CANCER.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91e60599f832f80c9b1dac81344eca4d
https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5062
https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5062
Autor:
Yutong Zhao, Evgeny V. Berdyshev, Roger A. Sabbadini, Peter V. Usatyuk, Nigel J. Pyne, Joe G.N. Garcia, Susan Pyne, Satish Kalari, Irina Gorshkova, Viswanathan Natarajan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 1, p e16571 (2011)
PLoS One
PLoS ONE, Vol 6, Iss 1, p e16571 (2011)
PLoS One
Background Earlier we have shown that extracellular sphingosine-1-phosphate (S1P) induces migration of human pulmonary artery endothelial cells (HPAECs) through the activation of S1P1 receptor, PKCε, and PLD2-PKCζ-Rac1 signaling cascade. As endothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da049af1d2c33c1e251a4908ae9326d7
https://pubmed.ncbi.nlm.nih.gov/21304987
https://pubmed.ncbi.nlm.nih.gov/21304987