Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Sathyen A. Prabhu"'
Autor:
Sathyen A. Prabhu, Omar Moussa, Christophe Gonçalves, Judith H. LaPierre, Hsiang Chou, Fan Huang, Vincent R. Richard, Pault Y. M. Ferruzo, Elizabeth M. Guettler, Isabel Soria-Bretones, Laura Kirby, Natascha Gagnon, Jie Su, Jennifer Silvester, Sai Sakktee Krisna, April A. N. Rose, Karen E. Sheppard, David W. Cescon, Frédérick A. Mallette, Rene P. Zahedi, Christoph H. Borchers, Sonia V. del Rincon, Wilson H. Miller
Publikováno v:
Molecular Cancer Therapeutics. 22:192-204
Aberrant cell-cycle progression is characteristic of melanoma, and CDK4/6 inhibitors, such as palbociclib, are currently being tested for efficacy in this disease. Despite the promising nature of CDK4/6 inhibitors, their use as single agents in melan
Autor:
Wilson H. Miller, Sonia V. del Rincon, Christoph H. Borchers, Rene P. Zahedi, Frédérick A. Mallette, David W. Cescon, Karen E. Sheppard, April A. N. Rose, Sai Sakktee Krisna, Jennifer Silvester, Jie Su, Natascha Gagnon, Laura Kirby, Isabel Soria-Bretones, Elizabeth M. Guettler, Pault Y. M. Ferruzo, Vincent R. Richard, Fan Huang, Hsiang Chou, Judith H. LaPierre, Christophe Gonçalves, Omar Moussa, Sathyen A. Prabhu
List of differentially expressed proteins annotated by cluster with pathway analysis in BLM cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00d6e0729cc0511a260e55cb63185dc
https://doi.org/10.1158/1535-7163.22523137
https://doi.org/10.1158/1535-7163.22523137
Autor:
Wilson H. Miller, Sonia V. del Rincon, Christoph H. Borchers, Rene P. Zahedi, Frédérick A. Mallette, David W. Cescon, Karen E. Sheppard, April A. N. Rose, Sai Sakktee Krisna, Jennifer Silvester, Jie Su, Natascha Gagnon, Laura Kirby, Isabel Soria-Bretones, Elizabeth M. Guettler, Pault Y. M. Ferruzo, Vincent R. Richard, Fan Huang, Hsiang Chou, Judith H. LaPierre, Christophe Gonçalves, Omar Moussa, Sathyen A. Prabhu
Supplementary Figure 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86493477a22be05a8f3fb8ee7bc0d5d5
https://doi.org/10.1158/1535-7163.22523134
https://doi.org/10.1158/1535-7163.22523134
Autor:
Wilson H. Miller, Sonia V. del Rincon, Christoph H. Borchers, Rene P. Zahedi, Frédérick A. Mallette, David W. Cescon, Karen E. Sheppard, April A. N. Rose, Sai Sakktee Krisna, Jennifer Silvester, Jie Su, Natascha Gagnon, Laura Kirby, Isabel Soria-Bretones, Elizabeth M. Guettler, Pault Y. M. Ferruzo, Vincent R. Richard, Fan Huang, Hsiang Chou, Judith H. LaPierre, Christophe Gonçalves, Omar Moussa, Sathyen A. Prabhu
Aberrant cell-cycle progression is characteristic of melanoma, and CDK4/6 inhibitors, such as palbociclib, are currently being tested for efficacy in this disease. Despite the promising nature of CDK4/6 inhibitors, their use as single agents in melan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73bca9689b5ed09aa6384274f881d0f4
https://doi.org/10.1158/1535-7163.c.6543604
https://doi.org/10.1158/1535-7163.c.6543604
Autor:
Wilson H. Miller, Sonia V. del Rincon, Christoph H. Borchers, Rene P. Zahedi, Frédérick A. Mallette, David W. Cescon, Karen E. Sheppard, April A. N. Rose, Sai Sakktee Krisna, Jennifer Silvester, Jie Su, Natascha Gagnon, Laura Kirby, Isabel Soria-Bretones, Elizabeth M. Guettler, Pault Y. M. Ferruzo, Vincent R. Richard, Fan Huang, Hsiang Chou, Judith H. LaPierre, Christophe Gonçalves, Omar Moussa, Sathyen A. Prabhu
Supplementary Figure 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6be1e09a691f9bec9d9a4fb2cabfd8d6
https://doi.org/10.1158/1535-7163.22523131.v1
https://doi.org/10.1158/1535-7163.22523131.v1
Autor:
Wilson H. Miller, Sonia V. del Rincon, Christoph H. Borchers, Rene P. Zahedi, Frédérick A. Mallette, David W. Cescon, Karen E. Sheppard, April A. N. Rose, Sai Sakktee Krisna, Jennifer Silvester, Jie Su, Natascha Gagnon, Laura Kirby, Isabel Soria-Bretones, Elizabeth M. Guettler, Pault Y. M. Ferruzo, Vincent R. Richard, Fan Huang, Hsiang Chou, Judith H. LaPierre, Christophe Gonçalves, Omar Moussa, Sathyen A. Prabhu
Supplementary Figure 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f3fc0dbf088b37e4e37432c377c3809
https://doi.org/10.1158/1535-7163.22523128.v1
https://doi.org/10.1158/1535-7163.22523128.v1
Autor:
Owen A. O'Connor, Olivier Elemento, Akanksha Verma, Serge Cremers, Renu Nandakumar, Jimmy Duong, Ying Wei, Xavier Jirau Serrano, Luigi Scotto, Yulissa Gonzalez, Paul M. Johannet, Kelly Zullo, Maximilian Lombardo, Sathyen A. Prabhu, Jennifer E. Amengual
Purpose: Pan-class I/II histone deacetylase (HDAC) inhibitors are effective treatments for select lymphomas. Isoform-selective HDAC inhibitors are emerging as potentially more targeted agents. ACY-1215 (ricolinostat) is a first-in-class selective HDA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b94422791cde262884e5e71d6e884a0
https://doi.org/10.1158/1078-0432.c.6525519.v1
https://doi.org/10.1158/1078-0432.c.6525519.v1
Data from Precision Targeting with EZH2 and HDAC Inhibitors in Epigenetically Dysregulated Lymphomas
Autor:
Jennifer E. Amengual, Olivier Elemento, Neil L. Kelleher, Serge Cremers, Renu Nandakumar, Changhong Qiao, Emily I. Chen, Swasti Mehta, Jeannie M. Camarillo, Nebiyu Abshiru, Prabhjot S. Mundi, Akanksha Verma, Yulissa Gonzalez, Yuxuan Liu, Sathyen A. Prabhu, Jennifer K. Lue
Purpose:Both gain-of-function enhancer of zeste homolog 2 (EZH2) mutations and inactivating histone acetyltransferases mutations, such as CREBBP and EP300, have been implicated in the pathogenesis of germinal center (GC)–derived lymphomas. We hypot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c25494f751d349c18a9a0f314e919e
https://doi.org/10.1158/1078-0432.c.6527655
https://doi.org/10.1158/1078-0432.c.6527655
Autor:
Jennifer E. Amengual, Olivier Elemento, Neil L. Kelleher, Serge Cremers, Renu Nandakumar, Changhong Qiao, Emily I. Chen, Swasti Mehta, Jeannie M. Camarillo, Nebiyu Abshiru, Prabhjot S. Mundi, Akanksha Verma, Yulissa Gonzalez, Yuxuan Liu, Sathyen A. Prabhu, Jennifer K. Lue
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3a7acc7afb6706436cb46f252d3e0a
https://doi.org/10.1158/1078-0432.22470681
https://doi.org/10.1158/1078-0432.22470681
Autor:
Nancy Braverman, Elie Khoury, Erminia Di Pietro, Sathyen A. Prabhu, Alicia M. Bolt, François-Michel Boisvert, Fan Huang, Sonia V. del Rincón, John K. Heath, Wilson H. Miller, Koren K. Mann, Raúl Ernesto Flores González, Alexandre Orthwein, Christophe Goncalves, Zi Yi Xu, Michael S. Dahabieh, Joelle Rémy-Sarrazin
Publikováno v:
Autophagy
Promoting the macroautophagy/autophagy-mediated degradation of specific proteins and organelles can potentially be utilized to induce apoptosis in cancer cells or sensitize tumor cells to therapy. To examine this concept, we enriched for autophagosom