Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sathish K. N. Yadav"'
Autor:
Kapil Gupta, Christine Toelzer, Maia Kavanagh Williamson, Deborah K. Shoemark, A. Sofia F. Oliveira, David A. Matthews, Abdulaziz Almuqrin, Oskar Staufer, Sathish K. N. Yadav, Ufuk Borucu, Frederic Garzoni, Daniel Fitzgerald, Joachim Spatz, Adrian J. Mulholland, Andrew D. Davidson, Christiane Schaffitzel, Imre Berger
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
BriSΔ, a SARS-CoV-2 variant from clinical isolate hCoV/England/02/2020, comprises a deletion in a spike cleavage site. The structure and molecular dynamics of this spike provides mechanistic insights into how the deletion modulates virus infectivity
Externí odkaz:
https://doaj.org/article/aca02d9ce50d4ddb8d2a53b3b352d716
Autor:
Christine Toelzer, Kapil Gupta, Sathish K. N. Yadav, Lorna Hodgson, Maia Kavanagh Williamson, Dora Buzas, Ufuk Borucu, Kyle Powers, Richard Stenner, Kate Vasileiou, Frederic Garzoni, Daniel Fitzgerald, Christine Payré, Gunjan Gautam, Gérard Lambeau, Andrew D. Davidson, Paul Verkade, Martin Frank, Imre Berger, Christiane Schaffitzel
Publikováno v:
Toelzer, C, Gupta, K, Yadav Kadapalakere, S, Hodgson, L R, Kavanagh Williamson, M, Buzas, D, Borucu, U, Powers, K T, Stenner, R A, Vasileiou, K, Garzoni, F, Fitzgerald, D J, Payré, C, Gautam, G, Lambeau, G, Davidson, A D, Verkade, P, Martin, F, Berger, I & Berger-Schaffitzel, C H 2022, ' The Free Fatty Acid-Binding Pocket is a Conserved Hallmark in Pathogenic β-Coronavirus Spike Proteins from SARS-CoV to Omicron ', Science Advances, vol. 8, no. 47, eadc9179 . https://doi.org/10.1101/2022.04.22.489083, https://doi.org/10.1126/sciadv.adc9179
As COVID-19 persists, severe acquired respiratory syndrome coronavirus-2 (SARS-CoV-2) Variants of Concern (VOCs) emerge, accumulating spike (S) glycoprotein mutations. S receptor-binding domain (RBD) comprises a free fatty acid (FFA)-binding pocket.
Autor:
Johannes F. Weijman, Sathish K. N. Yadav, Katherine J. Surridge, Jessica A. Cross, Ufuk Borucu, Judith Mantell, Derek N. Woolfson, Christiane Schaffitzel, Mark P. Dodding
Despite continuing progress in kinesin enzyme mechanochemistry and emerging understanding of the cargo recognition machinery, it is not known how these functions are coupled and controlled by the alpha-helical coiled coils encoded by a large componen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8659de7efca7974a4f2d3bb4295b8395
https://doi.org/10.1101/2022.04.28.489841
https://doi.org/10.1101/2022.04.28.489841