Výsledky vyhledávání - "Sathish Byrappa"

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Synthesis and Screening of Pro-apoptotic and Angio-inhibitory Activity of Novel Benzisoxazole Derivatives both In Vitro and In Vivo

Autor: Yashaswini Balaraju, Bharathi P. Salimath, Sumana Y. Kotian, Kavitha Rachaiah, Sathish Byrappa, K. M. L. Rai, Samudyata C. Prabhuswamimath

Publikováno v: Anti-cancer agents in medicinal chemistry. 19(6)

Background:Triple Negative Breast Cancer (TNBC) tends to be more aggressive than other types of breast cancer. Resistance to chemotherapy is a major obstacle hence there is a significant need for new antineoplastic drugs with multi-target potency. Nu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f74664a9c415fe268afc3cfac8f328
https://pubmed.ncbi.nlm.nih.gov/30648522

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Synthesis and biological evaluation of novel isoxazolines linked via piperazine to 2- benzoisothiazoles as potent apoptotic agents

Autor: Bharathi P. Salimath, Sathish Byrappa, Narayana U. Kudva N, Tenzin Kungyal, M. Harsha Raj, K. M. Lokanatha Rai

Publikováno v: European journal of medicinal chemistry. 126

Synthesis of 3-(4-((3-Phenyl-4,5-dihydroisoxazol-5-yl)methyl)piperazin-1-yl) benzoisothiazole derivatives (5a-i), which constitute a new class of isoxazolines, has been accomplished in regio-selective manner. These derivatives have been prepared by e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae75748a1c7e4a27aceaf8861d06235
https://pubmed.ncbi.nlm.nih.gov/27821324

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