Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Sathish Babu Vasamsetti"'
Autor:
Jonathan Florentin, Scott P. O’Neil, Lee L. Ohayon, Afaz Uddin, Sathish Babu Vasamsetti, Anagha Arunkumar, Samit Ghosh, Jennifer C. Boatz, Justin Sui, Corrine R. Kliment, Stephen Y. Chan, Partha Dutta
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Although it is well known that hypoxia incites unleashed cellular inflammation, the mechanisms of exaggerated cellular inflammation in hypoxic conditions are not known. We observed augmented proliferation of hematopoietic stem and progenitor cells (H
Externí odkaz:
https://doaj.org/article/6d8f81e84f044224a20f87ed6b49a267
Autor:
Danli Jiang, Wei Sun, Ting Wu, Meijuan Zou, Sathish Babu Vasamsetti, Xiaoyu Zhang, Yihan Zhao, Julie A. Phillippi, Amr H. Sawalha, Sina Tavakoli, Partha Dutta, Jonathan Florentin, Stephen Y. Chan, Tammy S. Tollison, null Di Wu, Jing Cui, Ian Huntress, Xinxia Peng, Toren Finkel, Gang Li
Publikováno v:
Nature Aging. 2:140-154
Accumulation of senescent cells with age is an important driver of aging and age-related diseases. However, the mechanisms and signaling pathways that regulate senescence remain elusive. In this report, we performed post-genome-wide association studi
Autor:
Ting Wu, Yuwei Wu, Danli Jiang, Wei Sun, Meijuan Zou, Sathish Babu Vasamsetti, Partha Dutta, Steven A. Leers, Wu Di, Gang Li
Publikováno v:
Aging Cell. 22
Autor:
Xinyi Zhang, Cameron S. McAlpine, Yoshiko Iwamoto, Partha Dutta, David Rohde, Maximilian J. Schloss, Sathish Babu Vasamsetti, Friedrich Felix Hoyer, Peter Libby, Emilie Coppin, Filip K. Swirski, Kamila Naxerova, Matthias Nahrendorf, Ganesh Modugu
Publikováno v:
Circulation. 142:244-258
Background: Diabetes mellitus is a prevalent public health problem that affects about one-third of the US population and leads to serious vascular complications with increased risk for coronary artery disease. How bone marrow hematopoiesis contribute
Autor:
Sathish Babu Vasamsetti, Niranjana Natarajan, Samreen Sadaf, Jonathan Florentin, Partha Dutta
Publikováno v:
The Journal of physiology.
Visceral adipose tissue (VAT) is a metabolic organ known to regulate fat mass, and glucose and nutrient homeostasis. VAT is an active endocrine gland that synthesizes and secretes numerous bioactive mediators called 'adipocytokines/adipokines' into s
Autor:
Samit Ghosh, Lee Ohayon, Justin Sui, Sathish Babu Vasamsetti, Stephen Chan, Jennifer C. Boatz, Corrine R. Kliment, Scott P. O’Neil, Anagha Arunkumar, Jonathan Florentin, Partha Dutta
Intermittent or chronic hypoxia is associated with morbidity and mortality in many diseases such as obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD), respectively. We found exaggerated inflammation with heightened number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44343e91f48fc8e691e079e18ef6dc7e
https://doi.org/10.21203/rs.3.rs-1000955/v1
https://doi.org/10.21203/rs.3.rs-1000955/v1
Autor:
Xinyi Zhang, Ansuman Chattopadhyay, Grant C. Bullock, Floyd Thoma, Suresh Mulukutla, Sasha Koul, Sathish Babu Vasamsetti, Dennis Kostka, Claudette M. St. Croix, Partha Dutta, Andrew Clugston, John Sembrat, Matthias Götberg, Emillie M Coppin, Mauricio Rojas, Jonathan Florentin
Publikováno v:
Circulation. 142
Introduction: Myocardial infarction (MI) is the major cause of morbidity and mortality in the western world. Insulin resistance is a major complication in patients with MI. Hypothesis: Loss of visceral adipose tissue (VAT) resident macrophages in MI
Autor:
John Sembrat, Marc A. Simon, Charles F. McTiernan, Partha Dutta, Wei Sun, Yuchi Han, Gil Speyer, Mehdi Nouraie, Mauricio Rojas, Adam Handen, Yingze Zhang, Frank C. Sciurba, Bryan J. McVerry, Ying Tang, Zeyu Xiong, Makenna E. Romanelli, Neil J. Kelly, Annie M. Watson, Yassmin Al Aaraj, Sathish Babu Vasamsetti, A. Smith, Seungchan Kim, Janet S. Lee, Dennis M. McNamara, Jeremy A. Mazurek, Yi-Yin Tai, Anjali Vaidya, Jingsi Zhao, Stephen Y. Chan
Publikováno v:
Circulation. 142
Introduction: Pulmonary arterial hypertension (PAH) is a morbid vascular disease where mutations of bone morphogenetic protein receptor 2 (BMPR2) control pulmonary endothelial pathophenotypes. Transcriptomic screening from endothelial cells (ECs) der
Autor:
Yi-Yin Tai, Linda Sanders, Mauricio Rojas, Scott P. O’Neil, Jingsi Zhao, Stephen Y. Chan, Anagha Arunkumar, Biruk Kassa, Annie M. Watson, Rajesh Kumar, Grant C. Bullock, Jonathan Florentin, Sathish Babu Vasamsetti, Brian B. Graham, Partha Dutta, John Sembrat
Publikováno v:
Cell Mol Immunol
Cellular & molecular immunology, vol 18, iss 2
Cellular & molecular immunology, vol 18, iss 2
Myeloid cells, such as neutrophils, are produced in the bone marrow in high quantities and are important in the pathogenesis of vascular diseases such as pulmonary hypertension (PH). Although neutrophil recruitment into sites of inflammation has been
Autor:
Ying Tang, John Sembrat, Annie M. Watson, Yingze Zhang, Jingsi Zhao, Partha Dutta, Emilie Coppin, Stephen Y. Chan, Sara O. Vargas, Jonathan Florentin, Sathish Babu Vasamsetti, Mauricio Rojas, Yi-Yin Tai
Publikováno v:
The Journal of Immunology. 200:3612-3625
Pulmonary inflammation, which is characterized by the presence of perivascular macrophages, has been proposed as a key pathogenic driver of pulmonary hypertension (PH), a vascular disease with increasing global significance. However, the mechanisms o