Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Sathiji Nageshwaran"'
Autor:
Theona Natisvili, Cihangir Yandim, Raquel Silva, Giulia Emanuelli, Felix Krueger, Sathiji Nageshwaran, Richard Festenstein
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165873 (2016)
Heterochromatinisation of pericentromeres, which in mice consist of arrays of major satellite repeats, are important for centromere formation and maintenance of genome stability. The dysregulation of this process has been linked to genomic stress and
Externí odkaz:
https://doaj.org/article/f40a1451f4c04e17a3b39ef7ec217906
Autor:
Balasundaram Kadirvelu, Constantinos Gavriel, Sathiji Nageshwaran, Jackson Ping Kei Chan, Suran Nethisinghe, Stavros Athanasopoulos, Valeria Ricotti, Thomas Voit, Paola Giunti, Richard Festenstein, A. Aldo Faisal
Publikováno v:
Nature Medicine. 29:86-94
Friedreichʼs ataxia (FA) is caused by a variant of the Frataxin (FXN) gene, leading to its downregulation and progressively impaired cardiac and neurological function. Current gold-standard clinical scales use simplistic behavioral assessments, whic
Autor:
Paola Giunti, Ping Kei Jackson Chan, Stavros Athanasopoulos, Valeria Ricotti, Balasundaram Kadirvelu, Constantinos Gavriel, Thomas Voit, A. Aldo Faisal, Sathiji Nageshwaran, Richard Festenstein
Friedreich’s ataxia (FA) is a neurodegenerative disease caused by the epigenetic repression of the Frataxin gene modulating mitochondrial activity in the brain, which has a diffuse phenotypic impact on patients’ motor behavior. Therefore, with cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c57a6492a286fec5f7c0333b096d9192
http://hdl.handle.net/10044/1/99760
http://hdl.handle.net/10044/1/99760
Autor:
Raghav Murthy, Sarit S. Cohen, Sathiji Nageshwaran, Jennifer L. Cohen, Barry Love, Ali N. Zaidi, Simone Jhaveri, Alice Chan
Publikováno v:
JACC Case Reports
JACC: Case Reports, Vol 3, Iss 2, Pp 230-235 (2021)
JACC: Case Reports, Vol 3, Iss 2, Pp 230-235 (2021)
Eisenmenger syndrome refers to any untreated congenital cardiac defect with an intracardiac communication that leads to pulmonary arterial hypertension, reversal of intracardiac shunting, and cyanosis. We describe a 40-year-old cyanotic patient with
Autor:
James J. Collins, Angela Tung, Sathiji Nageshwaran, Alissa Lance-Byrne, George M. Church, Nan Cher Yeo, Alejandro Chavez, Xiaoge Guo
Publikováno v:
J Vis Exp
The outlined protocol describes streamlined methods for the efficient and cost-effective generation of Cas9-associated guide RNAs. Two alternative strategies for guide RNA (gRNA) cloning are outlined based on the usage of the Type IIS restriction enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c43f6f525f60d8e1b13056457e05ab
https://europepmc.org/articles/PMC6235376/
https://europepmc.org/articles/PMC6235376/
Part of the Drugs in series, this book provides an easily accessible pocket-sized guide to the use of medications when treating patients with neurological ailments. Drugs in Neurology covers the breadth of medications used in modern neurology, includ
This chapter includes drugs beginning with the letter [Q]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f287040d3c47175bd52c0c35a2084785
https://doi.org/10.1093/med/9780199664368.003.0033
https://doi.org/10.1093/med/9780199664368.003.0033
This chapter includes drugs beginning with the letter [L]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7b0917fbe8c4e061d5fd7ba653934bd
https://doi.org/10.1093/med/9780199664368.003.0029
https://doi.org/10.1093/med/9780199664368.003.0029
This chapter discusses the evidence-based pharmacological management of motor and non-motor (autonomic disease, dementia, psychosis, depression, and sleep disorder) Parkinson’s disease (PD) and Parkinson’s plus syndromes (progressive supranuclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ace7dfb5942ecd461adbf9a1f79d6d1
https://doi.org/10.1093/med/9780199664368.003.0009
https://doi.org/10.1093/med/9780199664368.003.0009
Primary neuroinflammatory disorders of the central nervous system (multiple sclerosis, neuromyelitis optica (NMO), transverse myelitis, optic neuritis, acute disseminated encephalomyelitis (ADEM), primary angiitis of the central nervous system, autoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93dea944aee3a4bf4ff5f3c9a6423880
https://doi.org/10.1093/med/9780199664368.003.0006
https://doi.org/10.1093/med/9780199664368.003.0006