Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Sathi Babu Chodisetti"'
Autor:
Adam J. Fike, Sathi Babu Chodisetti, Nathaniel E. Wright, Kristen N. Bricker, Phillip P. Domeier, Mark Maienschein-Cline, Aaron M. Rosenfeld, Sara A. Luckenbill, Julia L. Weber, Nicholas M. Choi, Eline T. Luning Prak, Malay Mandal, Marcus R. Clark, Ziaur S.M. Rahman
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112512- (2023)
Summary: Germinal centers (GCs), sites of antibody affinity maturation, are organized into dark (DZ) and light (LZ) zones. Here, we show a B cell-intrinsic role for signal transducer and activator of transcription 3 (STAT3) in GC DZ and LZ organizati
Externí odkaz:
https://doaj.org/article/90bb71ba5bd34d068395ef2779c48824
Autor:
Sathi Babu Chodisetti, Adam J. Fike, Phillip P. Domeier, Nicholas M. Choi, Chetna Soni, Ziaur S. M. Rahman
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
IL-10 producing B cells (B10 cells) play an important immunoregulatory role in various autoimmune and infection conditions. However, the factors that regulate their development and maintenance are incompletely understood. Recently, we and others have
Externí odkaz:
https://doaj.org/article/0379784cda97449b9d4f6aff24fdd7f5
Autor:
Pradeep K. Rai, Sathi Babu Chodisetti, Sudeep K. Maurya, Sajid Nadeem, Weiguang Zeng, Ashok K. Janmeja, David C. Jackson, Javed N. Agrewala
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-12 (2018)
Abstract Background The clinical trials conducted at Chingleput India suggest that BCG fails to protect against tuberculosis (TB) in TB-endemic population. Recent studies advocate that non-tuberculous mycobacteria and latent Mycobacterium tuberculosi
Externí odkaz:
https://doaj.org/article/657a45b5c2694d859269eae6c3f5c7f6
Autor:
Phillip P. Domeier, Sathi Babu Chodisetti, Stephanie L. Schell, Yuka Imamura Kawasawa, Melinda J. Fasnacht, Chetna Soni, Ziaur S.M. Rahman
Publikováno v:
Cell Reports, Vol 24, Iss 2, Pp 406-418 (2018)
Summary: Type 1 interferon (T1IFN) signaling promotes inflammation and lupus pathology, but its role in autoreactive B cell development in the antibody-forming cell (AFC) and germinal center (GC) pathways is unclear. Using a lupus model that allows f
Externí odkaz:
https://doaj.org/article/7b9796ea1cb348bc9d2f93a94e94cf06
Autor:
Pradeep K. Rai, Sathi Babu Chodisetti, Weiguang Zeng, Sajid Nadeem, Sudeep K. Maurya, Susanta Pahari, Ashok K. Janmeja, David C. Jackson, Javed N. Agrewala
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-14 (2017)
Abstract Background The current BCG vaccine induces only short-term protection against Mycobacterium tuberculosis (Mtb), suggesting its failure to generate long-lasting memory T cells. Previously, we have demonstrated that a self-adjuvanting peptide
Externí odkaz:
https://doaj.org/article/a8ed0d3d63b44cb6ad28a929d7b37732
Autor:
Weshely Kujur, Rama Krishna Gurram, Sudeep K. Maurya, Sajid Nadeem, Sathi Babu Chodisetti, Nargis Khan, Javed Naim Agrewala
Publikováno v:
Autoimmunity, Vol 50, Iss 5, Pp 317-328 (2017)
Multiple sclerosis (MS) is a highly detrimental autoimmune disease of the central nervous system. There is no cure for it but the treatment typically focuses on subsiding severity and recurrence of the disease. Experimental autoimmune encephalomyelit
Externí odkaz:
https://doaj.org/article/9126efc7a8d0449f8bea5bc43feb639b
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/6d842ae892d2474393737c0724333986
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54392 (2013)
B cells are an integral component in mounting humoral immune responses and they are also crucial in programming T cell mediated immunity. Usually, B cell activation is initiated by recognition of antigen through B cell receptor (BCR), followed by its
Externí odkaz:
https://doaj.org/article/22adb322a48f4aa59ee8daf4952ca96f
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20651 (2011)
Conventionally, signaling through BCR initiates sequence of events necessary for activation and differentiation of B cells. We report an alternative approach, independent of BCR, for stimulating resting B (RB) cells, by involving TLR-2 and CD40--mole
Externí odkaz:
https://doaj.org/article/1866f7ebb3734007b2a6513f0ced79b8
Autor:
Phillip P. Domeier, Kristen N. Bricker, Steven F. Ziegler, Nicholas M Choi, Adam J. Fike, Sara A. Luckenbill, Zia Ur Rahman, Stephanie L. Schell, Sathi Babu Chodisetti, Melinda J. Fasnacht
Publikováno v:
J Immunol
MicroRNAs (miRNAs) are involved in healthy B cell responses and the loss of tolerance in systemic lupus erythematosus (SLE), although the role of many miRNAs remains poorly understood. Dampening miR-21 activity was previously shown to reduce splenome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b4a29c87d45fc56fcb71b39512bdf6
https://doi.org/10.4049/jimmunol.2001039
https://doi.org/10.4049/jimmunol.2001039