Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Satheesh K. Sivasubramani"'
Autor:
B. Kim Lee Sim, Minglin Li, Manuel Osorio, Yun Wu, Tint T. Wai, Johnny W. Peterson, Eric R. James, Sumana Chakravarty, Lixin Gao, Rui Xu, Natasha KC, Richard E. Stafford, William S. Lawrence, Linsey A. Yeager, Jennifer E. Peel, Satheesh K. Sivasubramani, Ashok K. Chopra, Svetlana Filippova, Stephen L. Hoffman
Publikováno v:
npj Vaccines, Vol 2, Iss 1, Pp 1-7 (2017)
Counterterrorism: creating a safe, stable, easily stored anthrax vaccine A vaccine candidate for anthrax infection shows promise for improving preparedness for a biological attack. Bacillus anthracis, the bacterium responsible for anthrax is a top-ti
Externí odkaz:
https://doaj.org/article/e6ed55cb74e9406db34a5f3fb0bf3838
Autor:
William S. Lawrence, Jennifer E. Peel, Satheesh K. Sivasubramani, Wallace B. Baze, Elbert B. Whorton, David W. C. Beasley, Jason E. Comer, Dallas E. Hughes, Losee L. Ling, Johnny W. Peterson
Publikováno v:
Pathogens, Vol 9, Iss 9, p 773 (2020)
The use of antibiotics is a vital means of treating infections caused by the bacteria Bacillus (B.) anthracis. Importantly, with the potential future use of multidrug-resistant strains of B. anthracis as bioweapons, new antibiotics are needed as alte
Externí odkaz:
https://doaj.org/article/3a2163ea774f4eb198d83dbe641669d8
Autor:
Christopher K. Cote, Jennifer E. Peel, Samandra T. Demons, Jennifer K Tran, Lynda L. Miller, Chi-Lee C. Ho, Satheesh K Sivasubramani, Chiu-Yen Kao, Jennifer L. Shoe, David P Fetterer, Mikhail Martchenko Shilman, Johnny W. Peterson, Gloria Bartolo, Ryan C. McComb, Saleem Alameh, Kenneth A. Bradley, David W.C. Beasley, Stella Hartmann, Emiene Amali-Adekwu, William S Lawrence, Anastasia Levitin, Marina Chugunova, Joel West, Leeor Zilbermintz, Christopher P. Klimko, Luisa W. Cheng, Aram Derbedrossian, Stephanie A Halasahoris
Publikováno v:
ACS Infect Dis
[Image: see text] Anthrax is caused by Bacillus anthracis and can result in nearly 100% mortality due in part to anthrax toxin. Antimalarial amodiaquine (AQ) acts as a host-oriented inhibitor of anthrax toxin endocytosis. Here, we determined the phar
Autor:
Johnny W. Peterson, Elbert B. Whorton, Jason E. Comer, William S Lawrence, Satheesh K Sivasubramani, Dallas Hughes, Losee L Ling, David W.C. Beasley, Jennifer E. Peel, Wallace B. Baze
Publikováno v:
Pathogens, Vol 9, Iss 773, p 773 (2020)
Pathogens
Volume 9
Issue 9
Pathogens
Volume 9
Issue 9
The use of antibiotics is a vital means of treating infections caused by the bacteria Bacillus (B.) anthracis. Importantly, with the potential future use of multidrug-resistant strains of B. anthracis as bioweapons, new antibiotics are needed as alte
Autor:
Terry L. Juelich, Satheesh K Sivasubramani, Olivier Escaffre, Alexander N. Freiberg, Jennifer E. Peel, Terence E. Hill, Jennifer K. Smith, Tetsuro Ikegami, Benhur Lee, William S Lawrence, Colm Atkins, David E Perez, Arnold Park, Johnny W. Peterson, Lihong Zhang
Publikováno v:
The Journal of Infectious Diseases. 218:1602-1610
Background Nipah virus (NiV) is a paramyxovirus (genus Henipavirus) that can cause severe respiratory illness and encephalitis in humans. Transmission occurs through consumption of NiV-contaminated foods, and contact with NiV-infected animals or huma
Autor:
Thomas W. Geisbert, Viktoriya Borisevich, William S Lawrence, Satheesh K Sivasubramani, Krystle N. Agans, Chad E. Mire, Abhishek N. Prasad, Karla A. Fenton, Joan B. Geisbert
Publikováno v:
The Journal of infectious diseases. 221(Suppl 4)
The high case-fatality rates and potential for use as a biological weapon make Nipah virus (NiV) a significant public health concern. Previous studies assessing the pathogenic potential of NiV delivered by the aerosol route in African green monkeys (
Autor:
Vladimir L. Motin, Bethany L. Tiner, Elena V. Kozlova, Snehal S. Patel, Jian Sha, Jennifer E. Peel, Michelle L. Kirtley, William S Lawrence, Ashok K. Chopra, Satheesh K Sivasubramani, Johnny W. Peterson, Igor Patrikeev, Tatiana E. Erova, Jourdan A. Andersson, Duraisamy Ponnusamy, David McWilliams, Wallace B. Baze, Curtis Klages, Eric C. Fitts, Maxim V. Telepnev, Eric Rothe
Publikováno v:
Clinical and Vaccine Immunology. 23:586-600
Currently, no plague vaccine exists in the United States for human use. The capsular antigen (Caf1 or F1) and two type 3 secretion system (T3SS) components, the low-calcium-response V antigen (LcrV) and the needle protein YscF, represent protective a
Autor:
Stephen L. Hoffman, Sumana Chakravarty, Eric R. James, Manuel Osorio, Johnny W. Peterson, Lixin Gao, Richard E. Stafford, Tint T. Wai, Natasha Kc, Rui Xu, William S Lawrence, Svetlana Filippova, B. Kim Lee Sim, Satheesh K Sivasubramani, Linsey A. Yeager, Yun Wu, Jennifer E. Peel, Minglin Li, Ashok K. Chopra
Publikováno v:
NPJ Vaccines
npj Vaccines, Vol 2, Iss 1, Pp 1-7 (2017)
npj Vaccines, Vol 2, Iss 1, Pp 1-7 (2017)
The national blueprint for biodefense concluded that the United States is underprepared for biological threats. The licensed anthrax vaccine absorbed vaccine, BioThrax, requires administration of at least 3–5 intramuscular doses. The anthrax vaccin
Autor:
Manoj Bhaskaran, Jane L Holley, Peter J. Didier, Satheesh K. Sivasubramani, Chad J. Roy, Lara A. Doyle
Publikováno v:
Toxicologic Pathology. 42:573-581
Ricin toxin, a type 2 ribosome-inactivating protein and a category B bioterrorism agent, is produced from the seeds of castor oil plant ( Ricinus communis). Chronic pathological changes in survivors of aerosolized ricin exposure have not been reporte
Autor:
Atsuhiko Hasegawa, Smriti Mehra, Andrew A. Lackner, Marcelo J. Kuroda, Kasi E. Russell-Lodrigue, Kerstan J. Stuckey, Lara A. Doyle, Peter J. Didier, Deepak Kaushal, Chie Sugimoto, Chad J. Roy, James Blanchard, Satheesh K. Sivasubramani, Nadia A. Golden, Xavier Alvarez
Publikováno v:
The Journal of Infectious Diseases. 205:1203-1213
Tuberculosis is responsible for the deaths of >1.7 million people annually [1]. This situation is exacerbated by the emergence of drug-resistant Mycobacterium tuberculosis (Mtb) [2, 3], AIDS coinfection [4], and the failure of the BCG vaccine [5]. De