Awakening a latent carbon fixation cycle in Escherichia coli

Autor: Ari Satanowski, Beau Dronsella, Elad Noor, Bastian Vögeli, Hai He, Philipp Wichmann, Tobias J. Erb, Steffen N. Lindner, Arren Bar-Even

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)

Current efforts to establish synthetic carbon fixation in model heterotrophs rely on expression of heterologous enzymes. Here, the authors explore the presence and activity of a latent CO2-assimilation pathway in E. coli based only on endogenous enzy

Externí odkaz: https://doaj.org/article/2af5c18026284ec281d826ac053f0876

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Engineering the Reductive Glycine Pathway : A Promising Synthetic Metabolism Approach for C1-Assimilation

Autor: Nico J. Claassens, Ari Satanowski, Viswanada R. Bysani, Beau Dronsella, Enrico Orsi, Vittorio Rainaldi, Suzan Yilmaz, Sebastian Wenk, Steffen N. Lindner

Publikováno v: One-Carbon Feedstocks for Sustainable Bioproduction
One-Carbon Feedstocks for Sustainable Bioproduction ISBN: 9783031068539
One-Carbon Feedstocks for Sustainable Bioproduction. Cham: Springer

In recent years the reductive glycine pathway (rGlyP) has emerged as a promising pathway for the assimilation of formate and other sustainable C1-feedstocks for future biotechnology. It was originally proposed as an attractive “synthetic pathway”

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55fd6b5393fb018d26cfd2c5e451155
https://research.wur.nl/en/publications/engineering-the-reductive-glycine-pathway-a-promising-synthetic-m

Activating silent glycolysis bypasses inEscherichia coli

Autor: H. Schulz-Mirbach, Elad Noor, Beau Dronsella, V. A. Delmas, K. Marx, Anne Berger, Ivan Dubois, Arren Bar-Even, Ari Satanowski, Madeleine Bouzon, V. Doering, Steffen N. Lindner, V. Biletskaia, C. Iacometti, M. Hoenick

All living organisms share similar reactions within their central metabolism to provide precursors for all essential building blocks and reducing power. To identify whether alternative metabolic routes of glycolysis can operate inE. coli, we compleme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d392f8feea9471de98d7fb7ec26e31e3
https://doi.org/10.1101/2021.11.18.468982

Awakening a latent carbon fixation cycle in Escherichia coli

Autor: Philipp Wichmann, Tobias J. Erb, Elad Noor, Arren Bar-Even, Hai He, Ari Satanowski, Steffen N. Lindner, Bastian Vögeli, Beau Dronsella

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications, 11 (1)

Carbon fixation is one of the most important biochemical processes. Most natural carbon fixation pathways are thought to have emerged from enzymes that originally performed other metabolic tasks. Can we recreate the emergence of a carbon fixation pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6901aebbc209e38f4090a4453b6d2c0b
https://doi.org/10.1101/2020.05.18.102244