The Genetic Architecture of Parkinson's Disease in the AfrAbia Population: Current State and Future Perspectives.

Autor: Mohamed W; Basic Medical Science Department, Kulliyyah of Medicine, International Islamic University Malaysia, 25200 Kuantan, Pahang, Malaysia.; Clinical Pharmacology Department, Menoufia Medical School, Menoufia University, 3211 Menoufia, Egypt., Eltantawi MA; Department of Neurology, Faculty of Medicine, Delta University for Science and Technology, 11152 Gamasa, Egypt., Agarwal V; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD 20814, USA., Bandres-Ciga S; Centre for Alzheimer's Disease and Related Dementias (CARD), National Institute on Ageing (NIA), National Institutes of Health (NIH), Bethesda, MD 20892, USA., Makarious MB; Centre for Alzheimer's Disease and Related Dementias (CARD), National Institute on Ageing (NIA), National Institutes of Health (NIH), Bethesda, MD 20892, USA.; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, WC1N 3BG London, UK., Mecheri Y; Neurology Department, Dr Benbadis University Hospital, 25000 Constantine, Algeria., Zewde YZ; Department of Neurology, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia., Kamel WA; Department of Neurology, Beni-Suef University, 62511 Beni-Suef, Egypt., Al-Mubarak B; King Faisal Specialist Hospital and Research Center, 11564 Riyadh, Saudi Arabia., Alzoubi KH; Department of Pharmacy Practice and Pharmacotherapeutics, College of Pharmacy, University of Sharjah, 27272 Sharjah, United Arab Emirates., Kissani N; Department of Neurology, Marrakech Faculty of Medicine and Pharmacy, University Hospital Mohamed VI, 5244 Marrakech, Morocco., Alghamdi BS; Neuroscience and Geroscience Research Unit, King Fahd Medical Research Center, King Abdulaziz University, 21589 Jeddah, Saudi Arabia., Sassi SB; National Institute Mongi Ben Hmida of Neurology, 1007 Tunis, Tunisia.

Publikováno v: Journal of integrative neuroscience [J Integr Neurosci] 2024 Aug 19; Vol. 23 (8), pp. 152.

A pathogenic variant in RAB32 causes autosomal dominant Parkinson's disease and activates LRRK2 kinase.

Autor: Gustavsson EK; Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA., Follett J; McKnight Brain Institute, Department of Neurology, University of Florida, Gainesville, Florida, USA.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada., Trinh J; Institute of Neurogenetics, University of Lübeck, Ratzeburger Allee 160, Lübeck 23538, Germany.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada., Barodia SK; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, USA., Real R; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.; UCL Movement Disorders Centre, University College London, London WC1N 3BG, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA., Liu Z; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, USA., Grant-Peters M; Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Fox JD; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada., Appel-Cresswell S; Pacific Parkinson's Research Centre, Djavad Mowafaghian Centre for Brain Health, Division of Neurology, University of British Columbia, Vancouver, BC, Canada., Stoessl AJ; Pacific Parkinson's Research Centre, Djavad Mowafaghian Centre for Brain Health, Division of Neurology, University of British Columbia, Vancouver, BC, Canada., Rajput A; Movement Disorders Program, Division of Neurology, University of Saskatchewan and Saskatchewan Health Authority, Saskatoon, SK, Canada., Rajput AH; Movement Disorders Program, Division of Neurology, University of Saskatchewan and Saskatchewan Health Authority, Saskatoon, SK, Canada., Auer R; Department of Pathology, University of Saskatchewan and Saskatchewan Health Authority, Saskatoon, SK, Canada., Tilney R; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.; UCL Movement Disorders Centre, University College London, London WC1N 3BG, UK., Sturm M; Institute for Medical Genetics and Applied Genomics, University of Tübingen, Germany., Haack TB; Institute for Medical Genetics and Applied Genomics, University of Tübingen, Germany., Lesage S; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Inserm, CNRS, Paris, France., Tesson C; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Inserm, CNRS, Paris, France., Brice A; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Inserm, CNRS, Paris, France.; Assistance Publique Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, Département de Neurologie, Centre d'Investigation Clinique Neurosciences, DMU Neuroscience, Paris, France., Vilariño-Güell C; Department of Medical Genetics, University of British Columbia, Vancouver V6T 1Z3, Canada., Ryten M; Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.; NIHR Great Ormond Street Hospital Biomedical Research Centre, University College London, London WC1N 1EH, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA., Goldberg MS; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, USA., West AB; Duke Center for Neurodegeneration and Neurotherapeutics, Department of Pharmacology and Cancer Biology, Duke University, 3 Genome Court, Durham 27710, North Carolina, USA., Hu MT; Division of Neurology, Nuffield Department of Clinical Neurosciences, University of Oxford, UK., Morris HR; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.; UCL Movement Disorders Centre, University College London, London WC1N 3BG, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA., Sharma M; Centre for Genetic Epidemiology, Institute for Clinical Epidemiology and Applied Biometry, University of Tübingen, Germany., Gan-Or Z; The Neuro (Montreal Neurological Institute-Hospital), Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada., Samanci B; Behavioural Neurology and Movement Disorders Unit, Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey., Lis P; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA., Tocino T; Queen Mary College, University of London, UK., Amouri R; Service de Neurologie, Institut National de Neurologie, La Rabta, Tunis 1007, Tunisia., Sassi SB; Service de Neurologie, Institut National de Neurologie, La Rabta, Tunis 1007, Tunisia., Hentati F; Service de Neurologie, Institut National de Neurologie, La Rabta, Tunis 1007, Tunisia., Tonelli F; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA., Alessi DR; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA., Farrer MJ; McKnight Brain Institute, Department of Neurology, University of Florida, Gainesville, Florida, USA.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Jan 18. Date of Electronic Publication: 2024 Jan 18.

Interaction of Mitochondrial Polygenic Score and Lifestyle Factors in LRRK2 p.Gly2019Ser Parkinsonism.

Autor: Lüth T; Institute of Neurogenetics, University of Lübeck, Lübeck, Germany., Gabbert C; Institute of Neurogenetics, University of Lübeck, Lübeck, Germany., Koch S; Institute of Medical Informatics and Statistics, Kiel University, University Hospital Schleswig-Holstein, Kiel, Germany., König IR; Institute of Medical Biometry and Statistics, University of Lübeck, Lübeck, Germany., Caliebe A; Institute of Medical Informatics and Statistics, Kiel University, University Hospital Schleswig-Holstein, Kiel, Germany., Laabs BH; Institute of Medical Biometry and Statistics, University of Lübeck, Lübeck, Germany., Hentati F; Neurology Department, National Institute of Neurology, Tunis, Tunisia., Sassi SB; Neurology Department, National Institute of Neurology, Tunis, Tunisia., Amouri R; Neurology Department, National Institute of Neurology, Tunis, Tunisia., Spielmann M; Institute of Human Genetics, University of Lübeck, Lübeck, Germany., Klein C; Institute of Neurogenetics, University of Lübeck, Lübeck, Germany., Grünewald A; Institute of Neurogenetics, University of Lübeck, Lübeck, Germany.; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg., Farrer MJ; Clinical Genomics, University of Florida, Gainesville, FL, USA., Trinh J; Institute of Neurogenetics, University of Lübeck, Lübeck, Germany.

Publikováno v: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2023 Oct; Vol. 38 (10), pp. 1837-1849. Date of Electronic Publication: 2023 Jul 21.

Acquired pial arteriovenous fistula secondary to cerebral cortical vein thrombosis: A case report and review of the literature.

Autor: Sammoud S; Department of Neuroradiology, Mongi Ben Hamida National Institute of Neurology Tunis, Tunisia.; Faculty of Medicine of Tunis, 37964University of Tunis El Manar, University of Tunis El Manar, Tunisia., Hammami N; Department of Neuroradiology, Mongi Ben Hamida National Institute of Neurology Tunis, Tunisia.; Faculty of Medicine of Tunis, 37964University of Tunis El Manar, University of Tunis El Manar, Tunisia., Turki D; Department of Neurology, Mongi Ben Hamida National Institute of Neurology Tunis, Tunisia.; Faculty of Medicine of Sfax, University of Sfax, Tunisia., Nabli F; Faculty of Medicine of Tunis, 37964University of Tunis El Manar, University of Tunis El Manar, Tunisia.; Department of Neurology, Mongi Ben Hamida National Institute of Neurology Tunis, Tunisia., Sassi SB; Faculty of Medicine of Tunis, 37964University of Tunis El Manar, University of Tunis El Manar, Tunisia.; Department of Neurology, Mongi Ben Hamida National Institute of Neurology Tunis, Tunisia., Belal S; Faculty of Medicine of Tunis, 37964University of Tunis El Manar, University of Tunis El Manar, Tunisia.; Department of Neurology, Mongi Ben Hamida National Institute of Neurology Tunis, Tunisia., Drissi C; Department of Neuroradiology, Mongi Ben Hamida National Institute of Neurology Tunis, Tunisia.; Faculty of Medicine of Tunis, 37964University of Tunis El Manar, University of Tunis El Manar, Tunisia., Hamouda MB; Department of Neuroradiology, Mongi Ben Hamida National Institute of Neurology Tunis, Tunisia.; Faculty of Medicine of Tunis, 37964University of Tunis El Manar, University of Tunis El Manar, Tunisia.

Publikováno v: The neuroradiology journal [Neuroradiol J] 2022 Aug; Vol. 35 (4), pp. 515-519. Date of Electronic Publication: 2021 Oct 05.

Stroke in the Middle-East and North Africa: A 2-year prospective observational study of stroke characteristics in the region-Results from the Safe Implementation of Treatments in Stroke (SITS)-Middle-East and North African (MENA).

Autor: Rukn SA; Department of Neurology, Rashid Hospital, Dubai Health Authority, Dubai, UAE., Mazya MV; Department of Neurology, Karolinska University Hospital, Stockholm, Sweden.; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden., Hentati F; Department of Neurology; Mongi Ben Hamida National Institute of Neurology, Tunis, Tunisia., Sassi SB; Department of Neurology; Mongi Ben Hamida National Institute of Neurology, Tunis, Tunisia., Nabli F; Department of Neurology; Mongi Ben Hamida National Institute of Neurology, Tunis, Tunisia., Said Z; Department of Neurology; Mongi Ben Hamida National Institute of Neurology, Tunis, Tunisia., Faouzi B; Department of Neurology, Hassan II University Hospital, Fez, Morocco., Hashim H; Department of Neurology, Rashid Hospital, Dubai Health Authority, Dubai, UAE., Abd-Allah F; Cairo University, Cairo, Egypt., Mansouri B; Imam Husain Hospital (IRHUS), Tehran, Iran., Kesraoui S; CHU de Blida, hôpital Franz Fanon, Blida, Algeria., Gebeily S; Neurosciences Research Center, Faculty of Medical Sciences, The Lebanese University, Hadath, Lebanon., Abdulrahman H; Department of Neurology, King Abdulaziz Medical City, Riyadh, Saudi Arabia., Akhtar N; Hamad General Hospital (QAHMG), Doha, Qatar., Ahmed N; Department of Neurology, Karolinska University Hospital, Stockholm, Sweden.; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden., Wahlgren N; Department of Neurology, Karolinska University Hospital, Stockholm, Sweden.; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden., Aref H; Stroke unit, Ain Shams University, Cairo, Egypt., Almekhlafi M; Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia., Moreira T; Department of Neurology, Karolinska University Hospital, Stockholm, Sweden.; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

Publikováno v: International journal of stroke : official journal of the International Stroke Society [Int J Stroke] 2019 Oct; Vol. 14 (7), pp. 715-722. Date of Electronic Publication: 2019 Mar 12.