Safety study of topical naltrexone therapy for diabetic skin wounds is confirmed in Göttingen mini-pigs.

Autor: McLaughlin PJ; Department of Neural and Behavioral Sciences, Penn State University College of Medicine, Hershey, Pennsylvania, USA., Sassani JW; Department of Ophthalmology, Penn State University College of Medicine, Hershey, Pennsylvania, USA., Zagon IS; Department of Neural and Behavioral Sciences, Penn State University College of Medicine, Hershey, Pennsylvania, USA.

Publikováno v: Drug development research [Drug Dev Res] 2023 Sep; Vol. 84 (6), pp. 1279-1284. Date of Electronic Publication: 2023 Jun 14.

Sex Differences in Diabetic Ocular Surface Complications and Dysregulation of the OGF-OGFr Pathway.

Autor: Zagon IS; Department of Neural and Behavioral Sciences, Penn State University College of Medicine, Hershey, Pennsylvania 17033, USA., Sassani JW; Department of Ophthalmology, Penn State University College of Medicine, Hershey, Pennsylvania 17033, USA., McLaughlin PJ; Department of Neural and Behavioral Sciences, Penn State University College of Medicine, Hershey, Pennsylvania 17033, USA.

Publikováno v: Journal of diabetes and clinical research [J Diabetes Clin Res] 2022; Vol. 4 (1), pp. 20-24.

Sex differences in the magnitude of diabetic ocular surface complications: Role of serum OGF.

Autor: Purushothaman I; Department of Neural and Behavioral Sciences, Penn State University College of Medicine, Hershey, PA 17033, United States., Zagon IS; Department of Neural and Behavioral Sciences, Penn State University College of Medicine, Hershey, PA 17033, United States., Sassani JW; Department of Ophthalmology,Penn State University College of Medicine, Hershey, PA 17033, United States., Zhou S; Division of Biostatistics and Bioinformatics, Department of Public Health Sciences, Penn State University College of Medicine, Hershey, PA 17033, United States., McLaughlin PJ; Department of Neural and Behavioral Sciences, Penn State University College of Medicine, Hershey, PA 17033, United States. Electronic address: pxm9@psu.edu.

Publikováno v: Physiology & behavior [Physiol Behav] 2021 Aug 01; Vol. 237, pp. 113436. Date of Electronic Publication: 2021 Apr 25.

Blockade of OGFr delays the onset and reduces the severity of diabetic ocular surface complications.

Autor: Zagon IS; Department of Neural and Behavioral Sciences, Penn State University College of Medicine, Hershey, PA 17033, USA., Sassani JW; Department of Ophthalmology, Penn State University College of Medicine, Hershey, PA 17033, USA., Purushothaman I; Department of Neural and Behavioral Sciences, Penn State University College of Medicine, Hershey, PA 17033, USA., McLaughlin PJ; Department of Neural and Behavioral Sciences, Penn State University College of Medicine, Hershey, PA 17033, USA.

Publikováno v: Experimental biology and medicine (Maywood, N.J.) [Exp Biol Med (Maywood)] 2021 Mar; Vol. 246 (5), pp. 629-636. Date of Electronic Publication: 2020 Nov 17.

Dysregulation of the OGF-OGFr pathway correlates with elevated serum OGF and ocular surface complications in the diabetic rat.

Autor: Zagon IS; Department of Neural and Behavioral Sciences, Penn State University College of Medicine, Hershey, PA 17033, USA., Sassani JW; Department of Ophthalmology, Penn State University College of Medicine, Hershey, PA 17033, USA., Purushothaman I; Department of Neural and Behavioral Sciences, Penn State University College of Medicine, Hershey, PA 17033, USA., McLaughlin PJ; Department of Neural and Behavioral Sciences, Penn State University College of Medicine, Hershey, PA 17033, USA.

Publikováno v: Experimental biology and medicine (Maywood, N.J.) [Exp Biol Med (Maywood)] 2020 Sep; Vol. 245 (15), pp. 1414-1421. Date of Electronic Publication: 2020 Jul 08.