Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Saskia van Stockum"'
Publikováno v:
European Journal of Neuroscience. 37:163-172
Many studies have shown that Parkinson's disease (PD) affects not only the ability to generate voluntary saccades but also the ability to suppress reflexive saccades (hyper-reflexivity). To further investigate these apparently contradictory effects o
Publikováno v:
Journal of Clinical Neuroscience. 19:1119-1124
Reflexive saccades (fast eye movements) and voluntary saccades activate overlapping parts of the oculomotor system. It is assumed that striatal dopamine depletion in Parkinson’s disease (PD) only affects the voluntary saccadic system and that the o
Autor:
Sridhar Alla, Tracy R. Melzer, C Graham, John C. Dalrymple-Alford, Saskia van Stockum, Jonathan R. Osborne, Deborah F. Mason, Jane Eagle, Laëtitia Debernard, David Miller
Publikováno v:
Psychiatry research. 234(3)
Although deep grey matter (GM) involvement in multiple sclerosis (MS) is well documented, in-vivo multi-parameter magnetic resonance imaging (MRI) studies and association with detailed cognitive measures are limited. We investigated volumetric, diffu
Autor:
Saskia van Stockum, Claudia A. M. Wheeler-Kingshott, David Miller, C Graham, Laëtitia Debernard, Deborah F. Mason, Tracy R. Melzer, John C. Dalrymple-Alford
Publikováno v:
Journal of neurology, neurosurgery, and psychiatry. 85(5)
Background Grey matter (GM) pathology in multiple sclerosis (MS) is associated with progressive long-term disability. Detection of GM abnormalities in early MS may therefore be valuable in understanding and predicting the long-term course. However, s
The influence of motor and cognitive impairment upon visually-guided saccades in Parkinson's disease
Autor:
John C. Dalrymple-Alford, Saskia van Stockum, Leslie Livingston, Daniel J. Myall, Tim J. Anderson, C Graham, Michael R. MacAskill, Toni L. Pitcher
Publikováno v:
Neuropsychologia. 50(14)
Studies of saccades in Parkinson's disease (PD) have seldom examined the influence of cognitive status, ranging from normal cognition, through mild cognitive impairment, to dementia. In a large and heterogeneous sample, we examined how motor and cogn
Publikováno v:
The European journal of neuroscience. 33(11)
Numerous studies have shown that Parkinson's disease (PD) affects the ability to generate voluntary saccades and the ability to suppress reflexive saccades. The effects of PD on the generation of reflexive saccades, however, are not clear. Some studi
Publikováno v:
Psychological research. 75(4)
A well-known eye movement paradigm combines saccades (fast eye movements) with a perceptual discrimination task. At a variable time after the onset of a central arrow cue indicating the target direction [the stimulus onset asynchrony (SOA)], discrimi
Publikováno v:
Neuropsychologia. 46(13)
Recent studies found evidence of impaired inhibition of saccades (fast eye movements) in non-demented people with PD. It has been suggested that impaired eye movement control reflects a general deficit of automatic response inhibition associated with