Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Saskia de Wildt"'
Autor:
Jolien Freriksen, Susan Cole, Joyce van der Heijden, Karen R Yeo, Trevor Johnson, Essam Kerwash, Marika de Hoop-Sommen, Rick Greupink, Janet Nooney, Saskia de Wildt, Ping Zhao
Publikováno v:
Gates Open Research, Vol 7 (2023)
Physiologically based pharmacokinetic (PBPK) models represent computational technology to characterize drug behavior within the context of detailed human physiology. Today, PBPK is routinely used in drug development and regulatory approval to support
Externí odkaz:
https://doaj.org/article/428afdfe2659434fa3aede8712f96746
Autor:
Maddalena Toma, Mariagrazia Felisi, Donato Bonifazi, Fedele Bonifazi, Viviana Giannuzzi, Giorgio Reggiardo, Saskia de Wildt, Adriana Ceci, TEDDY European Network of Excellence for Paediatric Research
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Objectives: In this paper, we investigated the effects of the European Paediatric Regulation (EC) N° 1901/2006 with respect to satisfying the paediatric therapeutic needs, assessed in terms of the increased number of paediatric medicinal products, n
Externí odkaz:
https://doaj.org/article/21996e36f4954970a9d231bc8c69ed5e
Autor:
Hendrika Hazendonk, Karin Fijnvandraat, Janske Lock, Mariëtte Driessens, Felix van der Meer, Karina Meijer, Marieke Kruip, Britta Laros-van Gorkom, Marjolein Peters, Saskia de Wildt, Frank Leebeek, Marjon Cnossen, Ron Mathôt
Publikováno v:
Haematologica, Vol 101, Iss 10 (2016)
The role of pharmacokinetic-guided dosing of factor concentrates in hemophilia is currently a subject of debate and focuses on long-term prophylactic treatment. Few data are available on its impact in the perioperative period. In this study, a popula
Externí odkaz:
https://doaj.org/article/8667ddb71a9e472fb29953a3b0cf09e6
Autor:
Jennifer Eymael, Martijn van den Broek, Laura Miesen, Valerie Villacorta Monge, Bartholomeus T van den Berge, Fieke Mooren, Vicky Luna Velez, Jelmer Dijkstra, Meyke Hermsen, Péter Bándi, Michiel Vermeulen, Saskia de Wildt, Brigith Willemsen, Sandrine Florquin, Roy Wetzels, Eric Steenbergen, Rafael Kramann, Marcus Moeller, Michiel F Schreuder, Jack FM Wetzels, Johan van der Vlag, Jitske Jansen, Bart Smeets
Publikováno v:
The journal of pathology 259(2), 149-162 (2023). doi:10.1002/path.6029
Journal of Pathology, 259, 149-162
Journal of pathology, 259(2), 149-162. John Wiley and Sons Ltd
Journal of Pathology, 259, 2, pp. 149-162
Journal of Pathology, 259(2), 149-162. John Wiley & Sons Ltd.
Journal of Pathology, 259, 149-162
Journal of pathology, 259(2), 149-162. John Wiley and Sons Ltd
Journal of Pathology, 259, 2, pp. 149-162
Journal of Pathology, 259(2), 149-162. John Wiley & Sons Ltd.
The journal of pathology (2022). doi:10.1002/path.6029
Published by Wiley, Bogner Regis[u.a.]
Published by Wiley, Bogner Regis[u.a.]
Autor:
Ian Chi Kei Wong, Saskia De Wildt
Publikováno v:
British Journal of Clinical Pharmacology, 88(12), 4962-4964. Wiley-Blackwell Publishing Ltd
British Journal of Clinical Pharmacology, 88, 4962-4964
British Journal of Clinical Pharmacology, 88, 12, pp. 4962-4964
British Journal of Clinical Pharmacology, 88, 4962-4964
British Journal of Clinical Pharmacology, 88, 12, pp. 4962-4964
Contains fulltext : 287160.pdf (Publisher’s version ) (Closed access)
Autor:
Jill Barber, Zubida M. Al-Majdoub, Narciso Couto, Martyn Howard, Yasmine Elmorsi, Daniel Scotcher, Naved Alizai, Saskia de Wildt, Felix Stader, Armin Sepp, Amin Rostami-Hodjegan, Brahim Achour
Publikováno v:
European Journal of Pharmaceutical Sciences, 182
Contains fulltext : 290153.pdf (Publisher’s version ) (Open Access)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6187b781fa739e84153ffb650bd54d
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/290153
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/290153
Autor:
Charlotte Koldeweij, Mirèse Kleuskens, Liesbeth Scheepers, Bryony Dean Franklin, Carlijn Litjens, Saskia de Wildt
Publikováno v:
Archives of Disease in Childhood. 108:A2.1-A2
IntroductionThe lack of evidence for drug dosing in pregnancy represents a large unmet need for pregnant women and their unborn child. This study examines Dutch stakeholders’ perceptions of model-informed dosing in pregnancy as part of an effort to
Autor:
Joyce van der Heijden, Jolien Freriksen, Marika de Hoop-Sommen, Rick Greupink, Saskia de Wildt
Publikováno v:
Archives of Disease in Childhood. 108:A4.3-A5
IntroductionMore than half of all drugs are still prescribed off-label to children. To support off-label dosing, pharmacokinetic (PK) data are needed. Physiologically-based pharmacokinetic (PBPK) models are increasingly used to study PK and guide dos
Autor:
Fenna Mahler, Katharine Cheng, Irja Lutsar, Begonya Nafria Escalera, Mark Turner, Saskia de Wildt
Publikováno v:
Archives of Disease in Childhood. 108:A4.1-A4
IntroductionChildren have the right to new and improved medicines.conect4children (c4c) aims to promote innovative trial design to optimise paediatric development plans while ensuring the voice of young patients and their families is heard. To addres
Publikováno v:
ORCID
In this special issue of the British Journal of Clinical Pharmacology, we highlight innovative methodologies in pediatric drug development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::360089df5fb530dc720d19be1e852d61
https://doi.org/10.22541/au.164704116.67205499/v1
https://doi.org/10.22541/au.164704116.67205499/v1