Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Saskia de Jongh"'
Autor:
Erik S.G. Stroes, John J.P. Kastelein, Saskia de Jongh, Barbara A. Hutten, Henk D. Bakker, Marc R. Lilien
Publikováno v:
Atherosclerosis, 163(1), 193-197. Elsevier Ireland Ltd
Objectives: in patients with familial hypercholesterolemia (FH), the propensity towards atherosclerosis may vary considerably. In the general population, a positive family history is associated with an increased risk for cardiovascular events. Since
Autor:
Mary B. Tuohy, John J.P. Kastelein, Saskia de Jongh, Michele Mercuri, Anton F. H. Stalenhoef, Henk D. Bakker
Publikováno v:
Clinical drug investigation, 22(8), 533-540. Adis International Ltd
Objective: To describe the rationale, design and baseline data of a study conducted to determine the efficacy, safety and tolerability of simvastatin in children and adolescents with heterozygous familial hypercholesterolaemia (heFH). Methods: Patien
Autor:
Russell S. Scott, Henk D. Bakker, John J.P. Kastelein, Patrice Perron, Leiv Ose, Aditi Sapre, Michael Stepanavage, Tamas Szamosi, Marie Lambert, A S Paul van Trotsenburg, Saskia de Jongh, Mary B. Tuohy, Dries Dobbelaere, M. Saborio, Barry Gumbiner, Claude Gagné, Michele Mercuri
Publikováno v:
Circulation, 106(17), 2231-2237. Lippincott Williams and Wilkins
Background— A multicenter, randomized, double-blind, placebo-controlled study was conducted to evaluate LDL cholesterol–lowering efficacy, overall safety, and tolerability and the influence on growth and pubertal development of simvastatin in a l
Autor:
Pernette R. W. de Sauvage Nolting, Angelique C.M. Jansen, John J.P. Kastelein, Emily S. van Aalst-Cohen, Saskia de Jongh
Publikováno v:
Seminars in vascular medicine, 4(1), 31-41. Thieme Medical Publishers
Heterozygous familial hypercholesterolemia (FH) is a common inherited disorder of lipoprotein metabolism. FH is characterized by elevated levels of low-density lipoprotein cholesterol, the presence of tendon xanthomas, and premature cardiovascular di
Autor:
John J.P. Kastelein, Jessica Rodenburg, Saskia de Jongh, Eric J.G. Sijbrands, Joep C. Defesche, Henk D. Bakker, Albert Wiegman
Publikováno v:
Pediatric research, 53(6), 1008-1012. Lippincott Williams and Wilkins
Pediatric Research, 53(6), 1008-1012. Lippincott Williams & Wilkins
Pediatric Research, 53(6), 1008-1012. Lippincott Williams & Wilkins
Children with familial hypercholesterolemia (FH) exhibit substantial variance of LDL cholesterol. In previous studies, family members of children with FH were included, which may have influenced results. To avoid such bias, we studied phenotype in 45
Autor:
Marc R. Lilien, Cornelis H. Schröder, Hein A. Koomans, Erik S.G. Stroes, Saskia de Jongh, Jos op 't Roodt
Publikováno v:
American Journal of Kidney Diseases, 41(3), 684-691. W B SAUNDERS CO-ELSEVIER INC
American journal of kidney diseases, 41(3), 684-691. W.B. Saunders Ltd
American journal of kidney diseases, 41(3), 684-691. W.B. Saunders Ltd
Background: Atherosclerotic complications are the main cause of death in adult patients with renal failure. Endothelial dysfunction is a hallmark of early atherosclerotic changes. The numerous risk factors for endothelial dysfunction present in adult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac46721622b5551529f6c2216b19a14
https://research.rug.nl/en/publications/654dbccf-e2ee-4437-9fb5-c3dfd605ee11
https://research.rug.nl/en/publications/654dbccf-e2ee-4437-9fb5-c3dfd605ee11
Autor:
Albert Wiegman, Jessica Rodenburg, John J.P. Kastelein, Henk D. Bakker, Eric J.G. Sijbrands, Saskia de Jongh, Joep C. Defesche
Publikováno v:
Circulation, 107(11), 1473-1478. Lippincott Williams and Wilkins
Circulation, 107, 1473-1478. Lippincott Williams & Wilkins
Circulation, 107, 1473-1478. Lippincott Williams & Wilkins
Background— Elevated LDL cholesterol (LDL-C) levels in childhood predict cardiovascular disease (CVD) later in life. Familial hypercholesterolemia (FH) represents the paradigm of this relation. Methods and Results— The objectives of this study we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d1262bb1e23c8431f6a4343f9547351
https://pure.amc.nl/en/publications/family-history-and-cardiovascular-risk-in-familial-hypercholesterolemia--data-in-more-than-1000-children(778978ca-f349-4cd2-a200-c8a3a711074c).html
https://pure.amc.nl/en/publications/family-history-and-cardiovascular-risk-in-familial-hypercholesterolemia--data-in-more-than-1000-children(778978ca-f349-4cd2-a200-c8a3a711074c).html
Autor:
Jos op 't Roodt, Henk D. Bakker, John J.P. Kastelein, Erik S.G. Stroes, Saskia de Jongh, Marc R. Lilien
Publikováno v:
Journal of the American College of Cardiology, 40(12), 2117-2121. Elsevier USA
OBJECTIVES This study was designed to determine whether simvastatin improves endothelial function in children with familial hypercholesterolemia (FH). BACKGROUND Endothelial function measured by flow-mediated dilation of the brachial artery (FMD) is