Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Saskia V. Vijver"'
Autor:
Saskia V. Vijver, Sarah Danklmaier, Lisa Pipperger, Raphael Gronauer, Gabriel Floriani, Hubert Hackl, Krishna Das, Guido Wollmann
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Oncolytic viruses are currently tested as a novel platform for cancer therapy. These viruses preferentially replicate in and kill malignant cells. Due to their microbial origin, treatment with oncolytic viruses naturally results in anti-viral respons
Externí odkaz:
https://doaj.org/article/3b96f4f2fe924248b1bdfa54a200326f
Autor:
Saskia V. Vijver, Akashdip Singh, Eline T. A. M. Mommers-Elshof, Jan Meeldijk, Ronald Copeland, Louis Boon, Sol Langermann, Dallas Flies, Linde Meyaard, M. Inês Pascoal Ramos
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The tumor microenvironment (TME) is a complex structure comprised of tumor, immune and stromal cells, vasculature, and extracellular matrix (ECM). During tumor development, ECM homeostasis is dysregulated. Collagen remodeling by matrix metalloprotein
Externí odkaz:
https://doaj.org/article/3c1e42c2d3424fdd8a18513ad402dbae
Publikováno v:
Cancers, Vol 12, Iss 2, p 519 (2020)
Neuroblastoma (NBL) is the most common extracranial solid tumor in childhood. Despite intense treatment, children with this high-risk disease have a poor prognosis. Immunotherapy showed a significant improvement in event-free survival in high-risk NB
Externí odkaz:
https://doaj.org/article/40828ff272a0418e9fc96a31fbe045a7
Autor:
Akashdip Singh, Alberto Miranda Bedate, Helen J von Richthofen, Saskia V Vijver, Michiel van der Vlist, Raphael Kuhn, Alexander Yermanos, Jürgen J Kuball, Can Kesmir, M Ines Pascoal Ramos, Linde Meyaard
Publikováno v:
eLife, Vol 13 (2024)
Despite major successes with inhibitory receptor blockade in cancer, the identification of novel inhibitory receptors as putative drug targets is needed due to lack of durable responses, therapy resistance, and side effects. Most inhibitory receptors
Externí odkaz:
https://doaj.org/article/967800a4473e405e96085b35ae0b275a
Publikováno v:
Current Opinion in Immunology. 69:65-71
Upon their activation, CD8+ T cells in the tumor micro-environment (TME) secrete cytokines such as IFNγ, TNFα, and IL-2. While over the past years a major interest has developed in the antigenic signals that induce such cytokine release, our unders
Autor:
Nicholas Willumsen, Linda Liu, Saskia V. Vijver, Sol Langermann, Eline Elshof, Dallas B. Flies, Stefan M. Willems, Ana Paucarmayta, Jahangheer Shaik, Linde Meyaard, Chang Song, Christina Jensen, Emma J de Ruiter, Jason Bosiacki, Zachary Cusumano, Linjie Tian, Akashdip Singh, Morten A. Karsdal, M. Inês Pascoal Ramos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0721053ffbc6190a92cc7b4c4f1ae6a7
https://doi.org/10.7554/elife.62927.sa2
https://doi.org/10.7554/elife.62927.sa2
Publikováno v:
Curr Opin Immunol
Upon their activation, CD8(+) T cells in the tumor micro-environment (TME) secrete cytokines such as IFNγ, TNFα, and IL-2. While over the past years a major interest has developed in the antigenic signals that induce such cytokine release, our unde
Autor:
Akashdip Singh, Jahangheer Shaik, M. Inês Pascoal Ramos, Sol Langermann, Linde Meyaard, Jason Bosiacki, Linjie Tian, Chang Song, Stefan M. Willems, Ana Paucarmayta, Emma J de Ruiter, Saskia V. Vijver, Zachary Cusumano, Dallas Flies, Eline Elshof, Linda Liu
Collagens are a primary component of the extracellular matrix and are functional ligands for the inhibitory immune receptor leukocyte associated immunoglobulin-like receptor-1 (LAIR-1). Leukocyte associated immunoglobulin-like receptor-2 (LAIR-2) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9071b466f412fb73a285d6b9f24fabc5
https://doi.org/10.1101/2020.10.21.349480
https://doi.org/10.1101/2020.10.21.349480
Autor:
Ana Paucarmayta, Emma J de Ruiter, Dallas Flies, Nicholas Willumsen, Akashdip Singh, Linjie Tian, Linda Liu, Saskia V. Vijver, Morten A. Karsdal, M. Inês Pascoal Ramos, Linde Meyaard, Chang Song, Stefan M. Willems, Sol Langermann, Jason Bosiacki, Jahangheer Shaik, Eline Elshof, Christina Jensen, Zachary Cusumano
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Collagens are a primary component of the extracellular matrix and are functional ligands for the inhibitory immune receptor leukocyte-associated immunoglobulin-like receptor (LAIR)-1. LAIR-2 is a secreted protein that can act as a decoy receptor by b
Publikováno v:
Cancers
Cancers, Vol 12, Iss 2, p 519 (2020)
Cancers, Vol 12, Iss 2, p 519 (2020)
Neuroblastoma (NBL) is the most common extracranial solid tumor in childhood. Despite intense treatment, children with this high-risk disease have a poor prognosis. Immunotherapy showed a significant improvement in event-free survival in high-risk NB