Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Saskia Schulthoff"'
Autor:
Marc Heinrich, Yonghoon Kwon, Alois Fürstner, Conny Wirtz, Saskia Schulthoff, James Y. Hamilton
Publikováno v:
Angewandte Chemie (International Ed. in English)
Total synthesis allowed the constitution of the cytotoxic marine macrolides of the formosalide family to be confirmed and their previously unknown stereostructure to be assigned with confidence. The underlying blueprint was inherently modular to ensu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22572b0a5fae12708fa215f21a02bc08
https://doi.org/10.1002/ange.202011472
https://doi.org/10.1002/ange.202011472
Publikováno v:
Chemistry - A European Journal. 24:109-114
The first total synthesis of the potent antibiotic disciformycin B (2) is described, which is exceptionally isomerization-prone and transforms into disciformycin A (1) even under notably mild conditions. To outweigh this bias, the approach to 2 hinge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b15e012731abfb7311e529a4662883
https://doi.org/10.1002/chem.201705550
https://doi.org/10.1002/chem.201705550
Publikováno v:
Angewandte Chemie (International ed. in English). 56(26)
Orevactaene and epipyrone A were previously thought to comprise the same polyunsaturated tail but notably different C-glycosylated 4-hydroxy-2-pyrone head groups. Total synthesis now shows that the signature bicyclic framework assigned to orevactaene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac25b08cf59a2b000b48c654ec94482
https://pubmed.ncbi.nlm.nih.gov/28557174
https://pubmed.ncbi.nlm.nih.gov/28557174
Autor:
Saskia Schulthoff, Alois Fürstner, Lucie Leseurre, Konrad Lehr, Barbara Gabor, Ronaldo Mariz, Yoshihiro Ueda
Publikováno v:
Chemistry - A European Journal. 21:219-227
Lactones are known to react with the reagent generated in situ from CCl4 and PPh3 in a Wittig-type fashion to give gem-dichloro-olefin derivatives. Such compounds are now shown to undergo reductive alkylation on treatment with organolithium reagents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd4606937ddac2561e745f4d3dda387
https://doi.org/10.1002/chem.201404873
https://doi.org/10.1002/chem.201404873
Autor:
Saskia Schulthoff, Alois Fürstner, Thomas N. Snaddon, Cornelia Wirtz, Richard Mynott, Philipp Buchgraber
Publikováno v:
Chemistry - A European Journal. 16:12133-12140
A productive total synthesis of both enantiomers of berkelic acid (1) is outlined that takes the structure revision of this bioactive fungal metabolite previously proposed by our group into account. The successful route relies on a fully optimized tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64da6f6945fffe9fc9832c5a2c3dccf
https://doi.org/10.1002/chem.201001133
https://doi.org/10.1002/chem.201001133
Autor:
Guillaume Chollet, Volker Hickmann, Jennifer Herrmann, Saskia Schulthoff, Takashi Nagano, Emilie Moulin, Alois Fürstner, Rolf Müller, Jiří Pospíšil
Publikováno v:
ResearcherID
A multitasking C-silylation strategy using the readily available compound 26 as a surrogate for cinnamic acid represents the key design element of a total synthesis of all known members of the ipomoeassin family of resin glyosides. This protecting gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87617901a6c9682dab0b82ff76a38672
https://doi.org/10.1002/chem.200901449
https://doi.org/10.1002/chem.200901449
Autor:
Yoshihiro Ueda, Barbara Gabor, Saskia Schulthoff, Alois Fuerstner, Konrad Lehr, Lucie Leseurre, Ronaldo Mariz
Publikováno v:
ChemInform. 46
Lactones are converted to methyl alkynes and dimethyl allenes in a two-step procedure utilizing a CCl4/PPh3—MeLi—system.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d384a864627374108b2c910c093d71b
https://doi.org/10.1002/chin.201521048
https://doi.org/10.1002/chin.201521048
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 19(11)
A concise total synthesis of spirastrellolide A methyl ester (1 a, R(1) =Me) as the parent compound of a series of highly cytotoxic marine macrolides is disclosed, which exploits and expands the flexibility of a synthesis plan previously developed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c430aa11999718da4a9c6db0cac6e20
https://pubmed.ncbi.nlm.nih.gov/23420709
https://pubmed.ncbi.nlm.nih.gov/23420709