Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Saskia Polling"'
Autor:
Anthony W. Purcell, Cheryl Chia, Yasmin M. Ramdzan, Dominic C.H. Ng, Angelique R. Ormsby, Saskia Polling, Paul A. Gleeson, Ivan Hong Wee Ng, Nathan P. Croft, Marie A. Bogoyevitch, Danny M. Hatters
Publikováno v:
Nature Methods. 9:467-470
We applied pulse-shape analysis (PulSA) to monitor protein localization changes in mammalian cells by flow cytometry. PulSA enabled high-throughput tracking of protein aggregation, translocation from the cytoplasm to the nucleus and trafficking from
Autor:
Jack A.M. Fransen, Marieke Willemse, Mietske Wijers, Gerda Venter, Helma Pluk, Saskia Polling, Bé Wieringa, Hanka Venselaar
Publikováno v:
European Journal of Cell Biology, 94, 114-27
European Journal of Cell Biology, 94, 2, pp. 114-27
European Journal of Cell Biology, 94, 2, pp. 114-27
Contains fulltext : 154023.pdf (Publisher’s version ) (Closed access) Subcellular partitioning of creatine kinase contributes to the formation of patterns in intracellular ATP distribution and the fuelling of cellular processes with a high and sudd
Autor:
Danny M. Hatters, Justin J. Yerbury, Bradley J. Turner, Andrew F. Hill, Yee-Foong Mok, Saskia Polling, Yasmin M. Ramdzan
Protein aggregation into intracellular inclusions is a key feature of many neurodegenerative disorders. A common theme has emerged that inappropriate self-aggregation of misfolded or mutant polypeptide sequences is detrimental to cell health. Yet pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a93872bf6eb1cdaa2cbaecf919f125
https://europepmc.org/articles/PMC3945328/
https://europepmc.org/articles/PMC3945328/
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1017
Defining the aggregation process of proteins formed by poly-amino acid repeats in cells remains a challenging task due to a lack of robust techniques for their isolation and quantitation. Sedimentation velocity methodology using fluorescence detected
Publikováno v:
Advances in experimental medicine and biology. 769
Polyglutamine (polyQ)-expansions in different proteins cause nine neurodegenerative diseases. While polyQ aggregation is a key pathological hallmark of these diseases, how aggregation relates to pathogenesis remains contentious. In this chapter, we r
Publikováno v:
Methods in Molecular Biology ISBN: 9781627034371
Defining the aggregation process of proteins formed by poly-amino acid repeats in cells remains a challenging task due to a lack of robust techniques for their isolation and quantitation. Sedimentation velocity methodology using fluorescence detected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc039925c0a07af08cc1c523c63d0f62
https://doi.org/10.1007/978-1-62703-438-8_4
https://doi.org/10.1007/978-1-62703-438-8_4
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461454335
Polyglutamine(polyQ)-expansions in differentproteins cause nine neurodegenerative diseases. While polyQ aggregation is a key pathological hallmark of these diseases, how aggregation relates to pathogenesis remains contentious. In this chapter, we rev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f464f0abe22a704836c4903976084a2
https://doi.org/10.1007/978-1-4614-5434-2_8
https://doi.org/10.1007/978-1-4614-5434-2_8