Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Saskia N. De Wildt"'
Autor:
Charlotte Koldeweij, Mirèse Kleuskens, Carlijn Litjens, Bryony Dean Franklin, Hubertina C. J. Scheepers, Saskia N. de Wildt
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Most women use medication during pregnancy. Pregnancy-induced changes in physiology may require antenatal dose alterations. Yet, evidence-based doses in pregnancy are missing. Given historically limited data, pharmacokinetic model
Externí odkaz:
https://doaj.org/article/6cffdb3842394d19908fbe1d7bbf869c
Autor:
Joyce E. M. van der Heijden, Marika de Hoop-Sommen, Noa Hoevenaars, Jolien J. M. Freriksen, Koen Joosten, Rick Greupink, Saskia N. de Wildt
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
IntroductionCritically ill patients show large variability in drug disposition due to e.g., age, size, disease and treatment modalities. Physiologically-based pharmacokinetic (PBPK) models can be used to design individualized dosing regimens taking t
Externí odkaz:
https://doaj.org/article/171193c1949d4eec9eea2f643a4373e1
Autor:
Thomas G. de Leeuw, Anneke A. Boerlage, Hanneke M. van West, Jeroen J. M. Renkens, Joost van Rosmalen, Lonneke M. E. Staals, Frank Weber, Dick Tibboel, Saskia N. de Wildt
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
ObjectiveApproximately 50% of adolescents who have undergone scoliosis surgery still experience severe pain one year postoperatively. We explored the postoperative pain trajectory and the potential value of preoperative Thermal Quantitative Sensory T
Externí odkaz:
https://doaj.org/article/6dcac22bde2a4816923089ae4312b3cb
Autor:
Eva Degraeuwe, Tessa van der Geest, Laura Persijn, Lieve Nuytinck, Ann Raes, Mark Turner, Ricardo M. Fernandes, Johan Vande Walle, Saskia N. de Wildt, IMI2 project conect4children (c4c) consortium, including National Hubs/Networks Belgian Pediatric Clinical Research Network (BPCRN) (Belgium) and Pedmed-NL (Netherlands)
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
IntroductionThe high failure rate of industry-driven pediatric clinical trials leads to insufficient timely labeling of drugs in children and a lack of scientific evidence, resulting in the persistently high off-label drug use. National clinical tria
Externí odkaz:
https://doaj.org/article/1fd098b6cdb94185abaf6ed28a55a8af
Autor:
Marika A. de Hoop-Sommen, Joyce E. M. van der Heijden, Jolien J. M. Freriksen, Rick Greupink, Saskia N. de Wildt
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
IntroductionModeling and simulation can support dosing recommendations for clinical practice, but a simple framework is missing. In this proof-of-concept study, we aimed to develop neonatal and infant gentamicin dosing guidelines, supported by a prag
Externí odkaz:
https://doaj.org/article/b9186a5e5a144cfead80e41d4eccd928
Autor:
Mireille M. Hermans, MSc, Suzanne G.M.A. Pasmans, MD, PhD, Peter C.J. de Laat, MD, PhD, Martijn G. Slieker, MD, PhD, Elodie J. Mendels, MD, Marlies de Graaf, MD, PhD, Hester R. Langeveld, MD, PhD, Renske Schappin, PhD, André B. Rietman, PhD, Corstiaan C. Breugem, MD, PhD, Johannes M.P.J. Breur, MD, PhD, Saskia N. de Wildt, MD, PhD, Martine F. Raphael, MD, PhD
Publikováno v:
JAAD International, Vol 11, Iss , Pp 137-139 (2023)
Externí odkaz:
https://doaj.org/article/b889b9323d994481a12ebae14880165d
Autor:
Mireille M. Hermans, Suzanne G.M.A. Pasmans, Marlies de Graaf, Aviël Ragamin, Elodie J. Mendels, Johannes M.P.J. Breur, Hester R. Langeveld, Martine F. Raphael, Peter C.J. de Laat, Saskia N. de Wildt, André B. Rietman, Corstiaan C. Breugem, Renske Schappin
Publikováno v:
Acta Dermato-Venereologica, Vol 103 (2023)
Parents of infants treated with beta-blockers for infantile haemangioma are often concerned about the long-term aesthetic outcome. This cross-sectional study assessed the influence on the long-term aesthetic outcome of characteristics of the infantil
Externí odkaz:
https://doaj.org/article/3996a19b07d74129a14f465c85f897c9
Autor:
Melina Steichert, Willi Cawello, Milica Bajcetic, Johannes M.P.J. Breur, Michiel Dalinghaus, Christoph Male, Saskia N. de Wildt, Stephanie Läer, on behalf of the LENA Consortium
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 28, Iss 12, p 335 (2023)
Background: Plasma renin activity (PRA) has gained relevance as prognostic marker in adults with heart failure. The use of PRA as a clinically meaningful parameter in children and children with heart failure requires a thorough knowledge of the facto
Externí odkaz:
https://doaj.org/article/55aadf2b6ebe43a6b0f05b814d93a592
Autor:
Mireille M. Hermans, Corstiaan C. Breugem, Renske Schappin, Emma Jonge Poerink, Elodie J. Mendels, Aviël Ragamin, Johannes M.P.J. Breur, Hester R. Langeveld, Martine F. Raphael, Peter C.J. de Laat, Saskia N. de Wildt, André B. Rietman, Suzanne G.M.A. Pasmans, Marlies de Graaf
Publikováno v:
Acta Dermato-Venereologica, Vol 102 (2022)
Infantile haemangiomas are common benign tumours of infancy, which can be treated effectively with beta-blockers such as propranolol and atenolol. Different types of beta-blockers may result in different long-term aesthetic outcomes. This study evalu
Externí odkaz:
https://doaj.org/article/bed7b22aeb84483383fe021135ae85c9
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/3365c2732ed34a6992c4b3928faef6d9