Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Saskia Meyer"'
Autor:
Jochen Buechner, Even Holth Rustad, Saskia Meyer, Thea Gjerdingen, Eirini Giannakopoulou, Muhammad Ali, Ingerid Weum Abrahamsen, Anna Pasetto, Ying Yuan, Johanna Olweus
Publikováno v:
HemaSphere, Vol 7, p e06642c9 (2023)
Externí odkaz:
https://doaj.org/article/c36169ed27c14fe48b3b69306a5dd450
Autor:
Saskia Meyer, Isaac Blaas, Ravi Chand Bollineni, Marina Delic-Sarac, Trung T. Tran, Cathrine Knetter, Ke-Zheng Dai, Torfinn Støve Madssen, John T. Vaage, Alice Gustavsen, Weiwen Yang, Lise Sofie Haug Nissen-Meyer, Karolos Douvlataniotis, Maarja Laos, Morten Milek Nielsen, Bernd Thiede, Arne Søraas, Fridtjof Lund-Johansen, Even H. Rustad, Johanna Olweus
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111995- (2023)
Summary: The emergence of SARS-CoV-2 variants of concern (VOC) is driven by mutations that mediate escape from neutralizing antibodies. There is also evidence that mutations can cause loss of T cell epitopes. However, studies on viral escape from T c
Externí odkaz:
https://doaj.org/article/8f80035bd4194790bb08bebf65988c88
Autor:
Simone Mester, Mitchell Evers, Saskia Meyer, Jeannette Nilsen, Victor Greiff, Inger Sandlie, Jeanette Leusen, Jan Terje Andersen
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Albumin has a serum half-life of 3 weeks in humans. This feature can be used to improve the pharmacokinetics of shorter-lived biologics. For instance, an albumin-binding domain (ABD) can be used to recruit albumin. A prerequisite for such design is t
Externí odkaz:
https://doaj.org/article/d68dea8700bb4629943b62d258a17e3a
Autor:
Mitchell Evers, Toine Ten Broeke, J.H. Marco Jansen, Maaike Nederend, Firas Hamdan, Karli R. Reiding, Saskia Meyer, Petra Moerer, Iris Brinkman, Thies Rösner, Robert Jan Lebbink, Thomas Valerius, Jeanette H.W. Leusen
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Current combination therapies elicit high response rates in B cell malignancies, often using CD20 antibodies as the backbone of therapy. However, many patients eventually relapse or develop progressive disease. Therefore, novel CD20 antibodies combin
Externí odkaz:
https://doaj.org/article/d9265821ed1e409289b5df381031fef1
Autor:
Frank Breitling, Gerhard Moldenhauer, Antonio Pezzutto, Oliver Schmetzer, Martin Lipp, Saskia Meyer, Regina Fertig, Hossein Panjideh, Dorothée Deppe, Sandra Lüttgau
Publikováno v:
Antibodies, Vol 2, Iss 2, Pp 338-352 (2013)
Using genetic engineering a humanized Fab fragment with specificity for CD19 was fused to a disulfide-stabilized single-chain antibody (dsFv) recognizing CD5. This format should show reduced immunogenicity and improved tissue penetration. The specifi
Externí odkaz:
https://doaj.org/article/ffd0b440b79a4a5788838607b4cc3b4f
Publikováno v:
Beton- und Stahlbetonbau. 117:888-900
Autor:
Peter Boross, Jeanette H.W. Leusen, Thomas Valerius, Stefan Lohse, Gerard Rouwendal, Ruud Ubink, István Németh, Sietse Q. Nagelkerke, M. Alejandra Beltrán Buitrago, J.H. Marco Jansen, Saskia Meyer, Geert van Tetering, Laura A.P.M. Meulenbroek, Maaike Nederend, Toine ten Broeke, Arianne M. Brandsma
Supplementary figure legends and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c48370f8dc02403421b6b6be685237d
https://doi.org/10.1158/2326-6066.22537123.v1
https://doi.org/10.1158/2326-6066.22537123.v1
Autor:
Peter Boross, Jeanette H.W. Leusen, Thomas Valerius, Stefan Lohse, Gerard Rouwendal, Ruud Ubink, István Németh, Sietse Q. Nagelkerke, M. Alejandra Beltrán Buitrago, J.H. Marco Jansen, Saskia Meyer, Geert van Tetering, Laura A.P.M. Meulenbroek, Maaike Nederend, Toine ten Broeke, Arianne M. Brandsma
Leukocyte-mediated cytotoxicity with IgG and IgA. 4 hour 51Cr-release assay by leukocytes using (A) A431 cells and (B) SK-BR-3 cells and 1 µg/ml mAb. Representative results of two (A) and four (B) experiments performed with different donors (Mean {p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba84ac6b42b6ec6082a4154802e930f
https://doi.org/10.1158/2326-6066.22537138.v1
https://doi.org/10.1158/2326-6066.22537138.v1
Autor:
Peter Boross, Jeanette H.W. Leusen, Thomas Valerius, Stefan Lohse, Gerard Rouwendal, Ruud Ubink, István Németh, Sietse Q. Nagelkerke, M. Alejandra Beltrán Buitrago, J.H. Marco Jansen, Saskia Meyer, Geert van Tetering, Laura A.P.M. Meulenbroek, Maaike Nederend, Toine ten Broeke, Arianne M. Brandsma
Efficacy of anticancer monoclonal antibodies (mAb) is limited by the exhaustion of effector mechanisms. IgG mAbs mediate cellular effector functions through FcγRs expressed on effector cells. IgA mAbs can also induce efficient tumor killing both in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c999899ed314911ffba086419467c90
https://doi.org/10.1158/2326-6066.c.6548326.v1
https://doi.org/10.1158/2326-6066.c.6548326.v1
Autor:
Peter Boross, Jeanette H.W. Leusen, Thomas Valerius, Stefan Lohse, Gerard Rouwendal, Ruud Ubink, István Németh, Sietse Q. Nagelkerke, M. Alejandra Beltrán Buitrago, J.H. Marco Jansen, Saskia Meyer, Geert van Tetering, Laura A.P.M. Meulenbroek, Maaike Nederend, Toine ten Broeke, Arianne M. Brandsma
PMN-mediated cytotoxicity is not increased by the combination of IgG and IgA against two targets. (A) Pooled data (8 donors) from ADCC assays were performed using purified PMNs isolated by Ficoll/Histopaque separation and A431-HER2 target cells eithe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9e1bb9e3deea67e57db5a3b039e313
https://doi.org/10.1158/2326-6066.22537126.v1
https://doi.org/10.1158/2326-6066.22537126.v1