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Akademický článek

Consequences of excessive glucosylsphingosine in glucocerebrosidase-deficient zebrafish.

Autor: Lindsey T. Lelieveld, Sophie Gerhardt, Saskia Maas, Kimberley C. Zwiers, Claire de Wit, Ernst H. Beijk, Maria J. Ferraz, Marta Artola, Annemarie H. Meijer, Christian Tudorache, Daniela Salvatori, Rolf G. Boot, Johannes M.F.G. Aerts

Publikováno v: Journal of Lipid Research, Vol 63, Iss 5, Pp 100199- (2022)

Abstract: In Gaucher disease (GD), the deficiency of glucocerebrosidase causes lysosomal accumulation of glucosylceramide (GlcCer), which is partly converted by acid ceramidase to glucosylsphingosine (GlcSph) in the lysosome. Chronically elevated blo

Externí odkaz: https://doaj.org/article/aa3d445ab3fa4e6ca569b196780b716f

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Akademický článek

Z-disc protein CHAPb induces cardiomyopathy and contractile dysfunction in the postnatal heart.

Autor: Willemijn van Eldik, Brigit den Adel, Jantine Monshouwer-Kloots, Daniela Salvatori, Saskia Maas, Ingeborg van der Made, Esther E Creemers, Derk Frank, Norbert Frey, Nicky Boontje, Jolanda van der Velden, Paul Steendijk, Christine Mummery, Robert Passier, Abdelaziz Beqqali

Publikováno v: PLoS ONE, Vol 12, Iss 12, p e0189139 (2017)

The Z-disc is a crucial structure of the sarcomere and is implicated in mechanosensation/transduction. Dysregulation of Z-disc proteins often result in cardiomyopathy. We have previously shown that the Z-disc protein Cytoskeletal Heart-enriched Actin

Externí odkaz: https://doaj.org/article/fdc129ae929545ad9bfbed2512288f1a

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Akademický článek

Origin, Fate, and Function of Epicardium-Derived Cells (EPDCs) in Normal and Abnormal Cardiac Development

Autor: Heleen Lie-Venema, Nynke M. S. van den Akker, Noortje A. M. Bax, Elizabeth M. Winter, Saskia Maas, Tuija Kekarainen, Rob C. Hoeben, Marco C. deRuiter, Robert E. Poelmann, Adriana C. Gittenberger-de Groot

Publikováno v: The Scientific World Journal, Vol 7, Pp 1777-1798 (2007)

During heart development, cells of the primary and secondary heart field give rise to the myocardial component of the heart. The neural crest and epicardium provide the heart with a considerable amount of nonmyocardial cells that are indispensable fo

Externí odkaz: https://doaj.org/article/d5fafa7023b34a5797e29fbd92ebdce1

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Figure S4 from CD4+ T Cell and NK Cell Interplay Key to Regression of MHC Class Ilow Tumors upon TLR7/8 Agonist Therapy

Autor: Thorbald van Hall, Sjoerd H. van der Burg, Ferry Ossendorp, Ramon Arens, Saskia Maas, Serenella Silvestri, Daniela C. Salvatori, Marjolein Sluijter, Elien M. Doorduijn

T cell phenotype after treatment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed60da620b4b5b7637c656af2898a66
https://doi.org/10.1158/2326-6066.22539304

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Figure legends from CD4+ T Cell and NK Cell Interplay Key to Regression of MHC Class Ilow Tumors upon TLR7/8 Agonist Therapy

Autor: Thorbald van Hall, Sjoerd H. van der Burg, Ferry Ossendorp, Ramon Arens, Saskia Maas, Serenella Silvestri, Daniela C. Salvatori, Marjolein Sluijter, Elien M. Doorduijn

Legends of supplementary figures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ddee11c469f5e8ccc496666f6214d3
https://doi.org/10.1158/2326-6066.22539301

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Data from CD4+ T Cell and NK Cell Interplay Key to Regression of MHC Class Ilow Tumors upon TLR7/8 Agonist Therapy

Autor: Thorbald van Hall, Sjoerd H. van der Burg, Ferry Ossendorp, Ramon Arens, Saskia Maas, Serenella Silvestri, Daniela C. Salvatori, Marjolein Sluijter, Elien M. Doorduijn

One of the next challenges in cancer immunotherapy is the resistance of tumors to T-cell–based treatments through loss of MHC class I. Here, we show that under these circumstances, the Toll-like receptor (TLR)-7/8 ligand imiquimod, but not the TLR3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef1d8a3fb684b57b044f7641b1508fc6
https://doi.org/10.1158/2326-6066.c.6549049.v1

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Expandable human cardiovascular progenitors from stem cells for regenerating mouse heart after myocardial infarction

Autor: Matthew J. Birket, Maria Gomes Fernandes, Daniela C.F. Salvatori, Sophie Gerhardt, Saskia Maas, Louise van der Weerd, Christine L. Mummery, Verena Schwach, Roula Tsonaka, Robert Passier

Publikováno v: Cardiovascular Research
Cardiovascular Research, 116(3), 545-553. Oxford University Press
Cardiovascular Research, 116(3), 545-553. OXFORD UNIV PRESS
Schwach, V, Fernandes, M G, Maas, S, Gerhardt, S, Tsonaka, R, van der Weerd, L, Passier, R, Mummery, C L, Birket, M J & Salvatori, D C F 2019, ' Expandable human cardiovascular progenitors from stem cells for regenerating mouse heart after myocardial infarction ', Cardiovascular research . https://doi.org/10.1093/cvr/cvz181
Cardiovascular research, 116(3), 545-553. Oxford University Press

Aims Cardiovascular diseases caused by loss of functional cardiomyocytes (CMs) are a major cause of mortality and morbidity worldwide due in part to the low regenerative capacity of the adult human heart. Human pluripotent stem cell (hPSC)-derived ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4f44c4a2057b77cedd837ab3a73e567
https://doi.org/10.1093/cvr/cvz181

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Elektronická kniha

Boom Chicago Presents the 30 Most Important Years in Dutch History

Autor: Andrew Moskos, Pep Rosenfeld, Matt Diehl, Saskia Maas

An exciting history of the improv group you've never heard of that changed comedy in America—this is the story of Boom Chicago in Amsterdam as told by its founders and most famous alumni'It's kind of crazy, the impact on culture so many Boom Chicag

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