Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Saskia M, van der Vies"'
Autor:
Annemieke J.M. Rozemuller, Jeroen J.M. Hoozemans, David Hondius, August B. Smit, Roel C. van der Schors, Elise S. van Haastert, Pim van Nierop, Saskia M. van der Vies, Ka Wan Li
Publikováno v:
Alzheimers & Dementia, 12(6), 654-668. Elsevier
Alzheimers & Dementia, 12(6), 654-68. Elsevier Inc.
Hondius, D, van Nierop, P, Li, K W, Hoozemans, J J M, van der Schors, R C, van Haastert, E S, van der Vies, S M, Rozemuller, A J M & Smit, A B 2016, ' Profiling the human hippocampal proteome at all pathologic stages of Alzheimer's disease ', Alzheimers & Dementia, vol. 12, no. 6, pp. 654-68 . https://doi.org/10.1016/j.jalz.2015.11.002
Hondius, D C, van Nierop, P, Li, K W, Hoozemans, J J M, van der Schors, R C, van Haastert, E S, van der Vies, S M, Rozemuller, A J M & Smit, A B 2016, ' Profiling the human hippocampal proteome at all pathologic stages of Alzheimer's disease ', Alzheimers & Dementia, vol. 12, no. 6, pp. 654-668 . https://doi.org/10.1016/j.jalz.2015.11.002
Alzheimers & Dementia, 12(6), 654-68. Elsevier Inc.
Hondius, D, van Nierop, P, Li, K W, Hoozemans, J J M, van der Schors, R C, van Haastert, E S, van der Vies, S M, Rozemuller, A J M & Smit, A B 2016, ' Profiling the human hippocampal proteome at all pathologic stages of Alzheimer's disease ', Alzheimers & Dementia, vol. 12, no. 6, pp. 654-68 . https://doi.org/10.1016/j.jalz.2015.11.002
Hondius, D C, van Nierop, P, Li, K W, Hoozemans, J J M, van der Schors, R C, van Haastert, E S, van der Vies, S M, Rozemuller, A J M & Smit, A B 2016, ' Profiling the human hippocampal proteome at all pathologic stages of Alzheimer's disease ', Alzheimers & Dementia, vol. 12, no. 6, pp. 654-668 . https://doi.org/10.1016/j.jalz.2015.11.002
INTRODUCTION: We performed a comprehensive quantitative proteomics study on human hippocampus tissue involving all Braak stages to assess changes in protein abundance over the various stages of Alzheimer's disease (AD).METHODS: Hippocampal subareas C
Autor:
Philip Scheltens, Andrea F.N. Rosenberger, Riet Hilhorst, Annemieke J.M. Rozemuller, Wiesje M. van der Flier, Jeroen J.M. Hoozemans, Leandro Garcia Barrado, Elisabeth Coart, Faris Naji, Saskia M. van der Vies
Publikováno v:
Journal of Alzheimer's Disease
Rosenberger, A F N, Hilhorst, R, Coart, E, Garcia Barrado, L, Naji, F, Rozemuller, A J M, van der Flier, W M, Scheltens, P, Hoozemans, J J M & van der Vies, S M 2015, ' Protein Kinase Activity Decreases with Higher Braak Stages of Alzheimer's Disease Pathology ', Journal of Alzheimer's Disease, vol. 49, no. 4, pp. 927-943 . https://doi.org/10.3233/JAD-150429
Journal of Alzheimer's Disease, 49(4), 927-943. IOS Press
Rosenberger, A F N, Hilhorst, R, Coart, E, Garcia Barrado, L, Naji, F, Rozemuller, A J M, van der Flier, W M, Scheltens, P, Hoozemans, J J M & van der Vies, S M 2016, ' Protein Kinase Activity Decreases with Higher Braak Stages of Alzheimer's Disease Pathology ', Journal of Alzheimer's Disease, vol. 49, no. 4, pp. 927-943 . https://doi.org/10.3233/JAD-150429
Rosenberger, A F N, Hilhorst, R, Coart, E, Garcia Barrado, L, Naji, F, Rozemuller, A J M, van der Flier, W M, Scheltens, P, Hoozemans, J J M & van der Vies, S M 2015, ' Protein Kinase Activity Decreases with Higher Braak Stages of Alzheimer's Disease Pathology ', Journal of Alzheimer's Disease, vol. 49, no. 4, pp. 927-943 . https://doi.org/10.3233/JAD-150429
Journal of Alzheimer's Disease, 49(4), 927-943. IOS Press
Rosenberger, A F N, Hilhorst, R, Coart, E, Garcia Barrado, L, Naji, F, Rozemuller, A J M, van der Flier, W M, Scheltens, P, Hoozemans, J J M & van der Vies, S M 2016, ' Protein Kinase Activity Decreases with Higher Braak Stages of Alzheimer's Disease Pathology ', Journal of Alzheimer's Disease, vol. 49, no. 4, pp. 927-943 . https://doi.org/10.3233/JAD-150429
Alzheimer’s disease (AD) is characterized by a long pre-clinical phase (20–30 years), during which significant brain pathology manifests itself. Disease mechanisms associated with pathological hallmarks remain elusive. Most processes associated w
Autor:
Bruno Hubesch, Achim Aigner, Reza J. Rasoulpour, Kerstin Schmidt, Alan Poole, Helmut Greim, Tokuo Sukata, Gunter Meister, Jay S. Petrick, Jan Verhaert, Nigel J. Gooderham, Madeleine Laffont, Hervé Seitz, Roland Buesen, Frank J. Slack, Emma L. Marczylo, Timothy W. Gant, Ursula G. Sauer, Jörg Hackermüller, Kenneth W. Witwer, Saskia M. van der Vies
Publikováno v:
Regulatory Toxicology and Pharmacology, 82, 127-139. Academic Press Inc.
Regulatory Toxicology and Pharmacology
Regulatory Toxicology and Pharmacology, Elsevier, 2016, 82, pp.127-139. ⟨10.1016/j.yrtph.2016.09.018⟩
Aigner, A, Buesen, R, Gant, T, Gooderham, N, Greim, H, Hackermuller, J, Hubesch, B, Laffont, M, Marczylo, E, Meister, G, Petrick, J S, Rasoulpour, R J, Sauer, U G, Schmidt, K, Seitz, H, Slack, F, Sukata, T, van der Vies, S M, Verhaert, J, Witwer, K W & Poole, A 2016, ' Advancing the use of noncoding RNA in regulatory toxicology: Report of an ECETOC workshop ', Regulatory Toxicology and Pharmacology, vol. 82, pp. 127-139 . https://doi.org/10.1016/j.yrtph.2016.09.018
Regulatory Toxicology and Pharmacology
Regulatory Toxicology and Pharmacology, Elsevier, 2016, 82, pp.127-139. ⟨10.1016/j.yrtph.2016.09.018⟩
Aigner, A, Buesen, R, Gant, T, Gooderham, N, Greim, H, Hackermuller, J, Hubesch, B, Laffont, M, Marczylo, E, Meister, G, Petrick, J S, Rasoulpour, R J, Sauer, U G, Schmidt, K, Seitz, H, Slack, F, Sukata, T, van der Vies, S M, Verhaert, J, Witwer, K W & Poole, A 2016, ' Advancing the use of noncoding RNA in regulatory toxicology: Report of an ECETOC workshop ', Regulatory Toxicology and Pharmacology, vol. 82, pp. 127-139 . https://doi.org/10.1016/j.yrtph.2016.09.018
The European Centre for the Ecotoxicology and Toxicology of Chemicals (ECETOC) organised a workshop to discuss the state-of-the-art research on noncoding RNAs (ncRNAs) as biomarkers in regulatory toxicology and as analytical and therapeutic agents. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847085db1b29f812860b87e80a671b46
https://research.vumc.nl/en/publications/e465638d-d163-426f-8021-4378630094ed
https://research.vumc.nl/en/publications/e465638d-d163-426f-8021-4378630094ed
Autor:
Robert H. H. van den Heuvel, Harm van Heerikhuizen, Douglas A. Simmons, Patrick J. Bakkes, Albert J. R. Heck, Ron M. A. Heeren, Carol V. Robinson, Esther van Duijn, Saskia M. van der Vies
It has been suggested that the bacterial GroEL chaperonin accommodates only one substrate at any given time, due to conformational changes to both the cis and trans ring that are induced upon substrate binding. Using electrospray ionization mass spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c870fb988ff496aaac991748dd4349c
https://ora.ox.ac.uk/objects/uuid:8ddc141b-229c-4f90-ab0c-6d87ce0e8407
https://ora.ox.ac.uk/objects/uuid:8ddc141b-229c-4f90-ab0c-6d87ce0e8407
Autor:
Marco Siderius, Annemarie Meenhuis, Xiao-Xian Yang, J.P. Bebelman, Patricija Hawle, Saskia M. van der Vies
Publikováno v:
FEMS Yeast Research. 7:796-807
Cdc37p, the p50 homolog of Saccharomyces cerevisiae, is an Hsp90 cochaperone involved in the targeting of protein kinases to Hsp90. Here we report a role for Cdc37p in osmoadaptive signalling in this yeast. The osmosensitive phenotype that is display
Publikováno v:
International Journal of Mass Spectrometry. 265:159-168
Using electrospray ionisation, non-covalently bound protein complexes can be transferred intact into the gas-phase and analysed and manipulated in a mass spectrometer. Here, two large (70–80 kDa) similar non-covalent protein complexes, gp31 and Gro
Autor:
Xiao Xian Yang, J.P. Bebelman, Patricija Hawle, Danielle Horst, Marco Siderius, Saskia M. van der Vies
Publikováno v:
Eukaryotic Cell. 6:521-532
The yeast Saccharomyces cerevisiae utilizes rapidly responding mitogen-activated protein kinase (MAPK) signaling cascades to adapt efficiently to a changing environment. Here we report that phosphorylation of Cdc37p, an Hsp90 cochaperone, by casein k
Publikováno v:
Analytical Chemistry. 78:7191-7196
Electron capture dissociation (ECD) of proteins in Fourier transform ion cyclotron resonance mass spectrometry usually leads to charge reduction and backbone-bond cleavage, thereby mostly retaining labile, intramolecular noncovalent interactions. In
Autor:
Michiel Molanus, Saskia M. van der Vies, Willem H. Mager, Marco Siderius, Kick Maurer, Xiao-Xian Yang
Publikováno v:
FEMS Yeast Research. 6:195-204
Exposure of Saccharomyces cerevisiae to high osmotic stress evokes a number of adaptive changes that are necessary for its survival. These adaptive responses are mediated via multiple mitogen-activated protein kinase pathways, of which the high-osmol
Autor:
J. Bulthuis, Gert van der Zwan, Aike Stortelder, Joost B. Buijs, Cees Gooijer, Johnny Hendriks, Saskia M. van der Vies
Publikováno v:
Journal of Physical Chemistry B, 110(49), 25050-8. American Chemical Society
Stortelder, A, Hendriks, J C, Buijs, J B, Bulthuis, J, Gooijer, C, van der Vies, S M & van der Zwan, G 2006, ' Hexamerization of the bacteriophage T4 capsid protein gp23 and its W13V mutant studied by time-resolved tryptophan fluorescence ', Journal of Physical Chemistry B, vol. 110, no. 49, pp. 25050-8 . https://doi.org/10.1021/jp064881t
Stortelder, A, Hendriks, J C, Buijs, J B, Bulthuis, J, Gooijer, C, van der Vies, S M & van der Zwan, G 2006, ' Hexamerization of the bacteriophage T4 capsid protein gp23 and its W13V mutant studied by time-resolved tryptophan fluorescence ', Journal of Physical Chemistry B, vol. 110, no. 49, pp. 25050-8 . https://doi.org/10.1021/jp064881t
The bacteriophage T4 capsid protein gp23 was studied using time-resolved and steady-state fluorescence of the intrinsic protein fluorophore tryptophan. In-vitro gp23 consists mostly of monomers at low temperature but forms hexamers at room temperatur