Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Saskia Güller"'
Autor:
Nicolaus Kröger, E-M Wagner, Tobias Berg, Oliver G. Ottmann, Andrea Wolf, Peter Bader, Saskia Güller, S K Metzelder, S Hünecke, Johannes Schetelig, Hubert Serve, Gesine Bug, Andreas Burchert
Publikováno v:
Leukemia
Maintenance therapy after allogeneic hematopoietic stem cell transplantation (HSCT) for acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) is conceptually attractive to prevent relapse, but has been hampered by the limited number of suita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5390059537c539f5e833951ec703e524
https://orca.cardiff.ac.uk/id/eprint/108724/8/leu2017242.pdf
https://orca.cardiff.ac.uk/id/eprint/108724/8/leu2017242.pdf
Autor:
Dieter Hoelzer, Sven de Vos, Claudia D. Baldus, Oliver G. Ottmann, Wolf-K. Hofmann, Saskia Güller, Martina Komor
Publikováno v:
STEM CELLS. 23:1154-1169
To better understand the transcriptional program that a ccompanies orderly lineage-specific hematopoietic differentiation, we performed serial oligonucleotide microarray analysis of human normal CD34+ bone marrow cells during lineage-specific differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654386dee3133ae959094e37b308fa9a
https://doi.org/10.1634/stemcells.2004-0171
https://doi.org/10.1634/stemcells.2004-0171
Autor:
Oliver G. Ottmann, Jun E Li, Dieter Hoelzer, Elena Puccetti, Martin Ruthardt, Saskia Güller, Tim Beissert
Publikováno v:
Oncogene. 22:6900-6908
Since the 19th century, arsenic (As2O3) has been used in the treatment of chronic myelogenous leukemia (CML) characterized by the t(9;22) translocation. As2O3 induces complete remissions in patients with acute promyelocytic leukemia. The response to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ecfd41727ccbaa02b2b1ce3cee8d32
https://doi.org/10.1038/sj.onc.1206747
https://doi.org/10.1038/sj.onc.1206747
Publikováno v:
BMC Cancer, Vol 6, Iss 1, p 262 (2006)
BMC Cancer
BMC Cancer
BackgroundThe reciprocal (9;22) translocation fuses thebcr(breakpoint cluster region) gene on chromosome 22 to theabl(Abelson-leukemia-virus) gene on chromosome 9. Depending on the breakpoint on chromosome 22 (the Philadelphia chromosome – Ph+) the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd28485162578445402e91b14f6f4399
http://publikationen.ub.uni-frankfurt.de/files/2092/1471_2407_6_262.pdf
http://publikationen.ub.uni-frankfurt.de/files/2092/1471_2407_6_262.pdf
Autor:
Oliver G. Ottmann, Elena Puccetti, Martin Ruthardt, Tim Beissert, Dieter Hoelzer, Andrea Bianchini, Clara Nervi, Saskia Güller, Simone Boehrer
Publikováno v:
Blood. 102(8)
Translocations involving the abl locus on chromosome 9 fuses the tyrosine kinase c-ABL to proteins harboring oligomerization interfaces such as BCR or TEL, enabling these ABL-fusion proteins (X-ABL) to transform cells and to induce leukemia. The ABL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98233b9b9f6ea79ed0e2519b97e91ca
https://pubmed.ncbi.nlm.nih.gov/12829585
https://pubmed.ncbi.nlm.nih.gov/12829585
Autor:
Roxana Bistrian, Bithia Grace, Reinhard Henschler, Xiaomin Zheng, Saskia Güller, Dieter Hoelzer, Gesine Bug, Martin Ruthardt, Oliver G. Ottmann
Publikováno v:
Blood. 104:214-214
In 95% of chronic myeloid leukemia (CML) and in 25% of acute lymphatic leukemia (ALL) the t(9;22) translocation fuses the bcr gene on chromosome 22 to the abl gene on chromosome 9 and vice versa. On 22+ the different breakpoints leads to the formatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb8466a5da5826d54e0c71d3181da005
https://doi.org/10.1182/blood.v104.11.214.214
https://doi.org/10.1182/blood.v104.11.214.214