Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Saskia E Bakker"'
Autor:
Suzannah J Rihn, Sam J Wilson, Nick J Loman, Mudathir Alim, Saskia E Bakker, David Bhella, Robert J Gifford, Frazer J Rixon, Paul D Bieniasz
Publikováno v:
PLoS Pathogens, Vol 9, Iss 6, p e1003461 (2013)
Genetic robustness, or fragility, is defined as the ability, or lack thereof, of a biological entity to maintain function in the face of mutations. Viruses that replicate via RNA intermediates exhibit high mutation rates, and robustness should be par
Externí odkaz:
https://doaj.org/article/34a40bd4ec5d4f0b983759833986b91d
Autor:
Saskia E. Bakker, David Bhella, Rosaria Brescia, Per Bullough, Daniel K. Clare, Bertram Daum, René A. W. Frank, Vicki A. M. Gold, Isobel Jackson Hirst, Werner Kühlbrandt, Penghan Lu, Mathew McLaren, Rebbekah Menday, Stephen P. Muench, Stephan Rauschenbach, Christopher J. Russo, Helen Saibil, Sjors H. W. Scheres, Archna R. Shah, Corinne Smith, James Torpey, Giulia Zanetti
Publikováno v:
Faraday Discussions. 240:312-322
Autor:
Natalie Al-Otaibi, Atieh Aminian J., Rex Frimpong Anane, Pieter Baatsen, Saskia E. Bakker, Julien Bergeron, Alok Bharadwaj, David Bhella, Thomas Braun, Rosaria Brescia, Per Bullough, Daniel K. Clare, Bertram Daum, Tim K. Esser, Irene del Mar Farinas Lucas, René A. W. Frank, Vicki A. M. Gold, Peter J. Harrison, Isobel Jackson Hirst, David P. Klebl, Werner Kühlbrandt, Christopher Morton, Stephen P. Muench, Mark Nakasone, Christopher J. Russo, Helen R. Saibil, Sjors H. W. Scheres, Vidhi Sehrawat, Archna R. Shah, Corinne Smith, Rebecca F. Thompson, Andrea Thorn, Giulia Zanetti
Publikováno v:
Faraday Discussions. 240:81-100
Autor:
Saskia E. Bakker, Julien Bergeron, Alok Bharadwaj, David Bhella, Per Bullough, Pak-Lee Chau, René A. W. Frank, Arjen J. Jakobi, Agnel Praveen Joseph, Werner Kühlbrandt, Indrajit Lahiri, Rebbekah Menday, Stephen P. Muench, Mark Nakasone, Dmitry Nerukh, Giulia Paris, Christopher J. Russo, Helen R. Saibil, Sjors H. W. Scheres, Vidhi Sehrawat, Archna R. Shah, Andrea Thorn, José Luis Vilas, Giulia Zanetti
Publikováno v:
Faraday Discussions. 240:229-242
Autor:
Salvatore Cinquerrui, Francesco Mancuso, Goran T. Vladisavljević, Saskia E. Bakker, Danish J. Malik
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Increasing antibiotic resistance in pathogenic microorganisms has led to renewed interest in bacteriophage therapy in both humans and animals. A “Trojan Horse” approach utilizing liposome encapsulated phages may facilitate access to phagocytic ce
Externí odkaz:
https://doaj.org/article/a7be87cad4584d36a5993e86d3f56227
Autor:
Michaela J Conley, Judith M Short, Andrew M Burns, James Streetley, Joshua Hutchings, Saskia E Bakker, B Joanne Power, Hussain Jaffery, Joanne Haney, Giulia Zanetti, Pablo R Murcia, Murray Stewart, Rachel Fearns, Swetha Vijayakrishnan, David Bhella
Publikováno v:
The EMBO journal. 41(3)
Human respiratory syncytial virus (RSV) causes severe respiratory illness in children and the elderly. Here, using cryogenic electron microscopy and tomography combined with computational image analysis and three-dimensional reconstruction, we show t
Autor:
Rachel Fearns, James Streetley, Giulia Zanetti, B. Joanne Power, Joshua Hutchings, Michaela J. Conley, Swetha Vijayakrishnan, Andrew M. Burns, Saskia E. Bakker, Judith M. Short, David Bhella, Murray Stewart, Hussain Jaffery
Human respiratory syncytial virus (RSV) causes severe respiratory illness in children and the elderly. Treatments for RSV disease are however limited and efforts to produce an effective vaccine have so far been unsuccessful. Understanding RSV virion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::830791556101d78d411c44ac690dd8e1
https://doi.org/10.1101/2021.08.04.455049
https://doi.org/10.1101/2021.08.04.455049
Autor:
Sophie J. Hesketh, Zoe Stroud, Alvin C. K. Teo, Timothy R. Dafforn, Sarah C. Lee, Corinne J. Smith, David I. Roper, Timothy J. Knowles, Corinne M. Spickett, Megha Rai, Pooja Sridhar, J. Malcolm East, Mayuriben J. Parmar, Stephen P Muench, Kailene S. Simon, Richard Collins, Vincent L. G. Postis, Saskia E. Bakker, C. Howard Barton, Naomi L. Pollock, Gregory Hurlbut
Most membrane proteins function through interactions with other proteins in the phospholipid bilayer, the cytosol or the extracellular milieu. Understanding the molecular basis of these interactions is key to understanding membrane protein function a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4184bd5543023d4d506e72952b00801a
Autor:
Derek Gatherer, Saskia E. Bakker, Wei Boon Yap, Richard McGonigle, Wen Siang Tan, Swee Tin Ong, David Bhella
Publikováno v:
Journal of Structural Biology
Virus-like particles composed of the core antigen of hepatitis B virus (HBcAg) have been shown to be an effective platform for the display of foreign epitopes in vaccine development. Heterologous sequences have been successfully inserted at both amin
Autor:
David Bhella, Saskia E. Bakker
Publikováno v:
The Biochemist. 35:14-19
Symmetry in virus architecture "A piece of bad news, wrapped up in protein", is an often-quoted description of viruses eloquently made by Sir Peter Medawar. Putting aside the added complexity of the lipid envelopes found in many viruses, this describ