Clinical Validation of the Fully Automated NeuMoDx HPV Assay for Cervical Cancer Screening

Autor: Daniëlle A. M. Heideman, Anja Oštrbenk Valenčak, Saskia Doorn, Jesper Bonde, Peter Hillemanns, Grega Gimpelj Domjanič, Jana Mlakar, Albertus T. Hesselink, Chris J. L. M. Meijer, Mario Poljak

Publikováno v: Viruses, Vol 14, Iss 5, p 893 (2022)

The NeuMoDx HPV assay is a novel fully automated, real-time PCR-based assay for the qualitative detection of high-risk human papillomavirus (HPV) DNA in cervical specimens. The assay specifically identifies HPV16 and HPV18 and concurrently detects 13

Externí odkaz: https://doaj.org/article/d95a7c88fa8e4fd690ef7b240bcdf492

Methylation markers FAM19A4 and miR124 ‐2 as triage strategy for primary human papillomavirus screen positive women: A large European multicenter study

Autor: Frederique J Vink, Johannes Berkhof, Helle Pedersen, Jesper Bonde, Peter M. van de Ven, Kate Cuschieri, Saskia Doorn, K. Ulrich Petry, Silvia de Sanjosé, Ditte Møller Ejegod, Chris J.L.M. Meijer, Albertus T. Hesselink, Anja Oštrbenk Valenčak, Wim Quint, Daniëlle A.M. Heideman, Grazyna Stanczuk, Mario Poljak, Arno Floore, Maaike C G Bleeker

Publikováno v: International Journal of Cancer. 148:396-405

In HPV cervical cancer screening, cytology is used as triage to counter the low specificity of HPV testing. VALID-SCREEN is a EU-multicentre, retrospective study conducted to evaluate the clinical performance of the FAM19A4/miR124-2 methylation-based

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ed74977cdd8d868bc7bc7ad65b29fe1
https://doi.org/10.1002/ijc.33320

Intra- and inter-laboratory agreement of the FAM19A4/mir124-2 methylation test:Results from an international study

Autor: Mario Poljak, Kate Cuschieri, Beate Rothe, Jesper Bonde, Wim Quint, Maaike C G Bleeker, Karl Ulrich Petry, Arno Floore, Anja Oštrbenk, Saskia Doorn, Helle Pedersen, Daniëlle A M Heideman, Montserrat Torres Hortal, Elia Alcaniz, Albertus T. Hesselink, Silvia de Sanjosé

Publikováno v: Floore, A, Hesselink, A, Oštrbenk, A, Alcaniz, E, Rothe, B, Pedersen, H, Torres Hortal, M, Doorn, S, Quint, W, Petry, K U, Poljak, M, Cuschieri, K, Bonde, J, de Sanjosé, S, Bleeker, M & Heideman, D 2019, ' Intra-and inter-laboratory agreement of the FAM19A4/mir124-2 methylation test : Results from an international study ', Journal of clinical laboratory analysis, vol. 33, no. 4, e22854, pp. e22854 . https://doi.org/10.1002/jcla.22854
Floore, A, Hesselink, A, Oštrbenk, A, Alcañiz Boada, E, Rothe, B, Pedersen, H K, Hortal, M T, Doorn, S, Quint, W, Petry, K U, Poljak, M, Cuschieri, K, Bonde, J, Sanjose, S D, Bleeker, M & Heideman, D A M 2019, ' Intra-and inter-laboratory agreement of the FAM19A4/mir124-2 methylation test: results from an international study ', Journal of Clinical Laboratory Analysis, vol. 33, no. 4, e22854 . https://doi.org/10.1002/jcla.22854
Journal of Clinical Laboratory Analysis
Journal of clinical laboratory analysis, 33(4):e22854. Wiley-Liss Inc.

BACKGROUND: HPV-based cervical screening detects women at an increased risk of cervical cancer and precancer. To differentiate among HPV-positive women those with (pre)cancer, triage testing is necessary. The detection of cancer-associated host-cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d7d4c3bd0837b4ded551580b9dfb3a
https://research.vumc.nl/en/publications/9f0ce4be-c5ff-4696-a64a-eec83746f1bd

Allelic Switching of

Autor: Arnoud, Boot, Jan, Oosting, Saskia, Doorn, Sarah, Ouahoud, Marina, Ventayol Garcia, Dina, Ruano, Hans, Morreau, Tom, van Wezel

Publikováno v: International Journal of Genomics

Allele-specific expression (ASE) is found in approximately 20-30% of human genes. During tumorigenesis, ASE changes due to somatic alterations that change the regulatory landscape. In colorectal cancer (CRC), many chromosomes show frequent gains or l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::35c81af237513c922e1a71a96c8428f3
https://pubmed.ncbi.nlm.nih.gov/31093489