Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Saskia C de Jager"'
Autor:
Gijs H M van Puijvelde, Amanda C Foks, Rosemarie E van Bochove, Ilze Bot, Kim L L Habets, Saskia C de Jager, Mariëtte N D Ter Borg, Puck van Osch, Louis Boon, Mariska Vos, Vivian de Waard, Johan Kuiper
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190962 (2018)
An abdominal aortic aneurysm (AAA) is a dilatation of the abdominal aorta leading to serious complications and mostly to death. AAA development is associated with an accumulation of inflammatory cells in the aorta including NKT cells. An important fa
Externí odkaz:
https://doaj.org/article/2ef143ea6d7b40768aea73f7394d8ed1
Autor:
Stephanie Maiwald, Suthesh Sivapalaratnam, Mahdi M Motazacker, Julian C van Capelleveen, Ilze Bot, Saskia C de Jager, Miranda van Eck, Jennifer Jolley, Johan Kuiper, Jonathon Stephens, Cornelius A Albers, C Ruben Vosmeer, Heleen Kruize, Daan P Geerke, Allard C van der Wal, Chris M van der Loos, John J P Kastelein, Mieke D Trip, Willem H Ouwehand, Geesje M Dallinga-Thie, G Kees Hovingh
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98289 (2014)
Genetic factors explain a proportion of the inter-individual variation in the risk for atherosclerotic events, but the genetic basis of atherosclerosis and atherothrombosis in families with Mendelian forms of premature atherosclerosis is incompletely
Externí odkaz:
https://doaj.org/article/d0ef6506d4f4491a80ea2afb192bac40
Autor:
Vanessa Frodermann, Gijs H van Puijvelde, Laura Wierts, H Maxime Lagraauw, Peter J van Santbrink, Ilze Bot, Johan Kuiper, Saskia C de Jager
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Introduction: Tolerogenic dendritic cells (DCs) have been previously described to protect against atherosclerosis. A tolerogenic phenotype in DCs can be induced by apoptotic cell clearance and these DCs can prevent inflammatory responses. In this stu
Autor:
Gijs H van Puijvelde, Amanda C Foks, Ilze Bot, Kim L Habets, Saskia C de Jager, Mariette N ter Borg, Theo J van Berkel, Paul Quax, Johan Kuiper
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Background: An abdominal aortic aneurysm (AAA) is a dilatation of the abdominal aorta mainly affecting men aged 60 years or older. Development of AAA is associated with an accumulation of inflammatory cells in the lesions such as NKT cells. The goal
Autor:
Anouk Wezel, H Maxime Lagraauw, Daniël van der Velden, Saskia C de Jager, Paul H Quax, Johan Kuiper, Ilze Bot
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Rationale: Activated mast cells have been identified in atherosclerotic plaques. As mast cells have the ability to release chemokines that mediate leukocyte fluxes, we propose that activated mast cells play a pivotal role in leukocyte recruitment dur
Autor:
Saskia C de Jager, Gijs H van Puijvelde, Adam A Anas, Martine Bot, Miriam Asbach, Kim L Habets, Amanda C Foks, Gerard Pasterkamp, Tom van der Poll, Johan Kuiper
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Background: Toll-like-receptors (TLRs) provide a critical link between innate and adaptive immune responses. It has been shown that TLR5 ligand Flagellin can enhance the suppressive capacity of regulatory T-cells (Treg), but can also functions as an
Autor:
Ilze Bot, Saskia C de Jager, Alma Zernecke, Christian Weber, Theo J van Berkel, Erik A Biessen
Publikováno v:
Circulation. 116
Activated mast cells have been identified in the perivascular tissue of human coronary artery plaques. As mast cells have been described to release a whole array of chemokines including interleukin 8 (IL-8) and MIP1 α, we propose that activated mast
Autor:
Saskia C De Jager, Beatriz Bermudez, Ilze Bot, Francisco J Muriana, Theo J van Berkel, Se J Lee, Rocio Abia, Erik A Biessen
Publikováno v:
Circulation. 116
Macrophage inhibitory cytokine-1 (MIC-1) is a distant member of the transforming growth factor β family with alleged anti-inflammatory activity that acts through an unknown receptor. Recently it was shown that elevated MIC-1 serum levels are an inde