Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Saskia A. G. M. Cillessen"'
Autor:
Marthe Minderman, Hildo C. Lantermans, Leonie J. Grüneberg, Saskia A. G. M. Cillessen, Richard J. Bende, Carel J. M. van Noesel, Marie José Kersten, Steven T. Pals, Marcel Spaargaren
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract The paracaspase mucosa-associated lymphoid tissue 1 (MALT1) is a protease and scaffold protein essential in propagating B-cell receptor (BCR) signaling to NF-κB. The deubiquitinating enzyme cylindromatosis (CYLD) is a recently discovered MA
Externí odkaz:
https://doaj.org/article/fa21a09a30c54eef9cb4825a4c293ec2
Autor:
Godefridus J. Peters, Frank P. A. van Gemert, Ietje Kathmann, Guru Reddy, Saskia A. G. M. Cillessen, Gerrit Jansen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Pralatrexate (Folotyn; PLX) and belinostat (Beleodaq; BLS) are registered for the treatment of patients with peripheral T-cell lymphoma (PTCL) and are being considered for other lymphomas. In this study we investigated whether BLS had the ability to
Externí odkaz:
https://doaj.org/article/3e3291e8ac454216bc476996dc1f37dc
Autor:
Sascha Gross, Roy L. van Wanrooij, Petula Nijeboer, Kyra A. Gelderman, Saskia A. G. M. Cillessen, Gerrit A. Meijer, Chris J. J. Mulder, Gerd Bouma, B. Mary E. von Blomberg, Hetty J. Bontkes
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
A small fraction of coeliac disease (CD) patients have persistent villous atrophy despite strict adherence to a gluten-free diet. Some of these refractory CD (RCD) patients develop a clonal expansion of lymphocytes with an aberrant phenotype, referre
Externí odkaz:
https://doaj.org/article/54bde9a07788469682507a9407ba1231
Autor:
Esther C.W. Breij, Hilma J. van der Horst, Simone C. Oostindie, Sonja Zweegman, Martine E D Chamuleau, Inger S. Nijhof, Marije B. Overdijk, Saskia A. G. M. Cillessen, Tuna Mutis, Anne T. Gelderloos
Publikováno v:
HemaSphere
HemaSphere, 5(1). Wolters Kluwer Health
HemaSphere, Vol 5, Iss 1, p e504 (2021)
Van Der Horst, H J, Oostindie, S C, Cillessen, S A G M, Gelderloos, A T, Overdijk, M B, Nijhof, I S, Zweegman, S, Chamuleau, M E D, Breij, E C W & Mutis, T 2021, ' Potent Preclinical Efficacy of DuoHexaBody-CD37 in B-Cell Malignancies ', HemaSphere, vol. 5, no. 1, pp. E504 . https://doi.org/10.1097/HS9.0000000000000504
HemaSphere, 5(1). Wolters Kluwer Health
HemaSphere, Vol 5, Iss 1, p e504 (2021)
Van Der Horst, H J, Oostindie, S C, Cillessen, S A G M, Gelderloos, A T, Overdijk, M B, Nijhof, I S, Zweegman, S, Chamuleau, M E D, Breij, E C W & Mutis, T 2021, ' Potent Preclinical Efficacy of DuoHexaBody-CD37 in B-Cell Malignancies ', HemaSphere, vol. 5, no. 1, pp. E504 . https://doi.org/10.1097/HS9.0000000000000504
Supplemental Digital Content is available in the text.
Autor:
Michel M van den Heuvel, Robert D Schouten, Linda J.W. Bosch, Nicole P Barlo, Daan van den Broek, Saskia A G M Cillessen, Kim Monkhorst, Daan C L Vessies, Anne S R van Lindert
Publikováno v:
JCO Precision Oncology
JCO Precision Oncology, 5, 1112-1121
JCO Precision Oncology, 5, pp. 1112-1121
JCO Precision Oncology, 5, 1112-1121
JCO Precision Oncology, 5, pp. 1112-1121
PURPOSE Comprehensive molecular profiling (CMP) plays an essential role in clinical decision making in metastatic non–small-cell lung cancer (mNSCLC). Circulating tumor DNA (ctDNA) analysis provides possibilities for molecular tumor profiling. In t
Autor:
Gerd Bouma, Chris J. J. Mulder, Tanja D. de Gruijl, Petula Nijeboer, Eskelina A. Neefjes-Borst, Hetty J. Bontkes, Amjad Hayat, Ekaterina S. Jordanova, Saskia A. G. M. Cillessen, Boudewina M. von Blomberg
Publikováno v:
British Journal of Haematology, 178(6), 988-991. Wiley-Blackwell
British journal of haematology, 178(6), 988-991. Wiley-Blackwell
Bontkes, H J, Jordanova, E S, Nijeboer, P, Neefjes-Borst, E A, Cillessen, S A G M, Hayat, A, Mulder, C J, Bouma, G, von Blomberg, B M & de Gruijl, T D 2017, ' High myeloid-derived suppressor cell frequencies in the duodenum are associated with enteropathy associated T-cell lymphoma and its precursor lesions ', British Journal of Haematology, vol. 178, no. 6, pp. 988-991 . https://doi.org/10.1111/bjh.14186
British journal of haematology, 178(6), 988-991. Wiley-Blackwell
Bontkes, H J, Jordanova, E S, Nijeboer, P, Neefjes-Borst, E A, Cillessen, S A G M, Hayat, A, Mulder, C J, Bouma, G, von Blomberg, B M & de Gruijl, T D 2017, ' High myeloid-derived suppressor cell frequencies in the duodenum are associated with enteropathy associated T-cell lymphoma and its precursor lesions ', British Journal of Haematology, vol. 178, no. 6, pp. 988-991 . https://doi.org/10.1111/bjh.14186
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa1cc51c88f6b27b7cdfc3aff464cdb
https://research.vumc.nl/en/publications/c15ec9ff-5af4-4251-8c3d-388f30881799
https://research.vumc.nl/en/publications/c15ec9ff-5af4-4251-8c3d-388f30881799
Autor:
Hendrik F. van Essen, Martijn W. Heymans, Hein B.A.C. Stockmann, Eric J. Th. Belt, Herman Bril, Marianne Tijssen, Gerrit A. Meijer, Saskia A. G. M. Cillessen, Pien M. Delis-van Diemen, Beatriz Carvalho, Jeroen A.M. Beliën
Publikováno v:
Journal of Surgical Oncology. 109:255-265
Background and Objectives Deregulation of apoptosis related genes may be associated with poor outcome in cancer. Aim of the present study was to investigate the prognostic role of expression levels of apoptosis related proteins in stage II and III co
Autor:
Anne T. Gelderloos, Martine E.D. Chamuleau, Hilma J. van der Horst, Simone C. Oostindie, Marije B. Overdijk, Tuna Mutis, Saskia A. G. M. Cillessen, Esther C.W. Breij
Publikováno v:
Blood. 132:4179-4179
CD37 is a tetraspanin molecule expressed on mature B-cells, but absent on normal stem cells and plasma cells. Due to this cellular distribution, which is highly similar to CD20, CD37 has gained attention as a target for B-cell lymphoma, especially fo
Autor:
Ahemd Harijadi, Saskia A. G. M. Cillessen, I. Bing Tan, Wim Vos, Bambang Hariwiyanto, Joost J. Oudejans, Jaap M. Middeldorp, D. F. Dukers, Chris J.L.M. Meijer, Philippe Busson
Publikováno v:
Modern Pathology, 18(7), 877-885. Nature Publishing Group
Oudejans, J J, Harijadi, A, Cillessen, S A G M, Busson, P, Tan, I B, Dukers, D F, Vos, W, Hariwiyanto, B, Middeldorp, J & Meijer, C J L M 2005, ' Absence of caspase 3 activation in neoplastic cells of nasopharyngeal carcinoma biopsies predicts rapid fatal outcome ', Modern Pathology, vol. 18, no. 7, pp. 877-885 . https://doi.org/10.1038/modpathol.3800398
Oudejans, J J, Harijadi, A, Cillessen, S A G M, Busson, P, Tan, I B, Dukers, D F, Vos, W, Hariwiyanto, B, Middeldorp, J & Meijer, C J L M 2005, ' Absence of caspase 3 activation in neoplastic cells of nasopharyngeal carcinoma biopsies predicts rapid fatal outcome ', Modern Pathology, vol. 18, no. 7, pp. 877-885 . https://doi.org/10.1038/modpathol.3800398
Poor prognosis in nasopharyngeal carcinoma patients may result from resistance to the apoptosis-inducing effect of radio- and/or chemotherapy. Apoptosis depends on proper activation of caspase 3, resulting in cleavage of key proteins like PARP-1. To
Autor:
Patty M. Jansen, Johan H. J. M. van Krieken, Jettie J.F. Muris, Saskia A. G. M. Cillessen, Joost J. Oudejans, N. Mehdi Jiwa, Hanneke C. Kluin-Nelemans, J. Alain Kummer, Wim Vos, Chad Gundy, Gert J. Ossenkoppele, Inge S. van Houdt, Chris J.L.M. Meijer
Publikováno v:
Blood, 105, 2916-23
Blood, 105(7), 2916-2923. AMER SOC HEMATOLOGY
Blood, 105, 7, pp. 2916-23
Blood, 105(7), 2916-2923. AMER SOC HEMATOLOGY
Blood, 105, 7, pp. 2916-23
Contains fulltext : 47593.pdf (Publisher’s version ) (Closed access) We used biopsy specimens of primary nodal diffuse large B-cell lymphoma (DLBCL) to investigate whether the inhibition of caspase 8 and/or 9 apoptosis signaling pathways predicts c