Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Saskia, Wedel"'
Autor:
Jörn Lötsch, Khayal Gasimli, Sebastian Malkusch, Lisa Hahnefeld, Carlo Angioni, Yannick Schreiber, Sandra Trautmann, Saskia Wedel, Dominique Thomas, Nerea Ferreiros Bouzas, Christian H Brandts, Benjamin Schnappauf, Christine Solbach, Gerd Geisslinger, Marco Sisignano
Publikováno v:
eLife, Vol 13 (2024)
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a serious therapy-limiting side effect of commonly used anticancer drugs. Previous studies suggest that lipids may play a role in CIPN. Therefore, the present study aimed to identify th
Externí odkaz:
https://doaj.org/article/2f70ecc6b60c49e0aa4c7ee6c353f55a
Autor:
Maksim Sendetski, Saskia Wedel, Kenta Furutani, Lisa Hahnefeld, Carlo Angioni, Jan Heering, Béla Zimmer, Sandra Pierre, Alexandra-Maria Banica, Klaus Scholich, Sorin Tunaru, Gerd Geisslinger, Ru-Rong Ji, Marco Sisignano
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110552- (2024)
Summary: Noxious stimuli activate nociceptive sensory neurons, causing action potential firing and the release of diverse signaling molecules. Several peptides have already been identified to be released by sensory neurons and shown to modulate infla
Externí odkaz:
https://doaj.org/article/9870422af084425992e7ef7e3feb5b83
Autor:
Saskia Wedel, Lisa Hahnefeld, Yannick Schreiber, Christian Namendorf, Tim Heymann, Manfred Uhr, Mathias V. Schmidt, Natasja de Bruin, Felix Hausch, Dominique Thomas, Gerd Geisslinger, Marco Sisignano
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-21 (2023)
Abstract Background Chemotherapy-induced neuropathic pain (CIPN) describes a pathological pain state that occurs dose-dependently as a side effect and can limit or even impede an effective cancer therapy. Unfortunately, current treatment possibilitie
Externí odkaz:
https://doaj.org/article/7393b95fee1a48c09212292b2adeaadf
Autor:
Saskia Wedel, Praveen Mathoor, Oliver Rauh, Tim Heymann, Cosmin I. Ciotu, Dominik C. Fuhrmann, Michael J. M. Fischer, Andreas Weigert, Natasja de Bruin, Felix Hausch, Gerd Geisslinger, Marco Sisignano
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-21 (2022)
Abstract Background Neuropathic pain is experienced worldwide by patients suffering from nerve injuries, infectious or metabolic diseases or chemotherapy. However, the treatment options are still limited because of low efficacy and sometimes severe s
Externí odkaz:
https://doaj.org/article/a1ae3ff5437d4071b8e640f89f13be07
Autor:
Jennifer Zimmermann, Alexandra Goretzki, Clara Meier, Sonja Wolfheimer, Yen-Ju Lin, Hannah Rainer, Maren Krause, Saskia Wedel, Gerd Spies, Frank Führer, Stefan Vieths, Stephan Scheurer, Stefan Schülke
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundRecently, bacterial components were shown to enhance immune responses by shifting immune cell metabolism towards glycolysis and lactic acid production, also known as the Warburg Effect. Currently, the effect of allergen products for immunot
Externí odkaz:
https://doaj.org/article/587e4ac925034b488b25d9fe6bff272a
Autor:
Fabian H. Knaup, Christian Meyners, Wisely Oki Sugiarto, Saskia Wedel, Margherita Springer, Carlo Walz, Thomas M. Geiger, Mathias Schmidt, Marco Sisignano, Felix Hausch
In recent years the selective inhibition of FKBP51 has emerged as a possible treatment for chronic pain, obesity-induced diabetes, or depression. All currently known advanced FKBP51-selective inhibitors, including the widely used SAFit2, contain a cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03081ad8bb2b0f20e4cbea12ac38d678
https://doi.org/10.26434/chemrxiv-2023-pzzcv
https://doi.org/10.26434/chemrxiv-2023-pzzcv
Autor:
Sisignano, Saskia Wedel, Lisa Hahnefeld, Mohamad Wessam Alnouri, Stefan Offermanns, Felix Hausch, Gerd Geisslinger, Marco
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 14274
Neuropathic pain is a pathological pain state with a broad symptom scope that affects patients after nerve injuries, but it can also arise after infections or exposure to toxic substances. Current treatment possibilities are still limited because of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::ed6be2adcd64842956203f0203562962
Autor:
Saskia, Wedel, Lisa, Hahnefeld, Mohamad Wessam, Alnouri, Stefan, Offermanns, Felix, Hausch, Gerd, Geisslinger, Marco, Sisignano
Publikováno v:
International journal of molecular sciences. 23(22)
Neuropathic pain is a pathological pain state with a broad symptom scope that affects patients after nerve injuries, but it can also arise after infections or exposure to toxic substances. Current treatment possibilities are still limited because of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1dda1b68ac9e720a1eedfa7f278c3c70
https://pubmed.ncbi.nlm.nih.gov/36430751
https://pubmed.ncbi.nlm.nih.gov/36430751