Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Saskia, Kropf"'
Autor:
Kathrin Philipp‐Abbrederis, Ken Herrmann, Stefan Knop, Margret Schottelius, Matthias Eiber, Katharina Lückerath, Elke Pietschmann, Stefan Habringer, Carlos Gerngroß, Katharina Franke, Martina Rudelius, Andreas Schirbel, Constantin Lapa, Kristina Schwamborn, Sabine Steidle, Elena Hartmann, Andreas Rosenwald, Saskia Kropf, Ambros J Beer, Christian Peschel, Hermann Einsele, Andreas K Buck, Markus Schwaiger, Katharina Götze, Hans‐Jürgen Wester, Ulrich Keller
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 4, Pp 477-487 (2015)
Abstract CXCR4 is a G‐protein‐coupled receptor that mediates recruitment of blood cells toward its ligand SDF‐1. In cancer, high CXCR4 expression is frequently associated with tumor dissemination and poor prognosis. We evaluated the novel CXCR4
Externí odkaz:
https://doaj.org/article/b94bc3fe20304d139146df2d3df76b5d
Autor:
Philipp M Kazmierczak, Andrei Todica, Franz-Josef Gildehaus, Heidrun Hirner-Eppeneder, Matthias Brendel, Ralf S Eschbach, Magdalena Hellmann, Konstantin Nikolaou, Maximilian F Reiser, Hans-Jürgen Wester, Saskia Kropf, Axel Rominger, Clemens C Cyran
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168248 (2016)
To investigate 68Ga-TRAP-(RGD)3 hybrid imaging for the in vivo monitoring of αvß3-integrin expression as biomarker of anti-angiogenic therapy effects in experimental breast cancer.Human breast cancer (MDA-MB-231) xenografts were implanted orthotopi
Externí odkaz:
https://doaj.org/article/c1995de093fb47818393409f4e5c6083
Autor:
Hans-Jürgen Wester, Alexander Wurzer, Wolfgang A. Weber, So Won Oh, Thomas Langbein, Eugene J. Teoh, Sohee Oh, Saskia Kropf, Matthias Eiber, Michael Herz, Markus Krönke
Publikováno v:
Journal of Nuclear Medicine. 61:702-709
Radiohybrid PSMA (rhPSMA) ligands, a new class of theranostic prostate-specific membrane antigen (PSMA)-targeting agents, feature fast 18F synthesis and utility for labeling with radiometals. Here, we assessed the biodistribution and image quality of
Autor:
Dietrich Beitzke, Xiang Li, Alexander Haug, Wei Yu, Hans Wester, Tim Wollenweber, Yongxiang Wei, Marcus Hacker, Xiaoli Zhang, Xia Lu, Saskia Kropf, Wolfgang Wadsak
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
Purpose Type 4 chemokine receptor (CXCR4) plays an important role in immune cell migration during the atherosclerosis progression. We aimed to evaluate [68Ga]Pentixafor positron emission tomography (PET) in combination magnetic resonance imaging (MRI
Autor:
Saskia Kropf, Wolfgang Wadsak, Hans-Juergen Wester, Marcus Hacker, Markus Mitterhauser, Barbara Kiesewetter-Wiederkehr, Asha Leisser, Markus Raderer, Marius E. Mayerhoefer, Markus Hartenbach, Alexander Haug, Sarah Pfaff
Publikováno v:
Theranostics. 9:3653-3658
MALT lymphomas express the chemokine receptor CXCR4 on a regular basis, and [68Ga]Ga-Pentixafor-PET has been shown to quantify CXCR4 expression non-invasively. We, therefore, aimed to evaluate [68Ga]Ga-Pentixafor-PET/MRI for the non-invasive assessme
Autor:
Laura B.N. Langer, Carsten Oliver Sahlmann, Saskia Kropf, Johannes Meller, Caroline Bouter, Yvonne Bouter, Bettina J. Wolf, Jens P. Bankstahl, Hans Wester, Birgit Meller
Publikováno v:
Nuklearmedizin. 57:198-203
Previous findings of our group showed the chemokine receptor CXCR4 as a suitable target in PET/CT-imaging of axial bone infections, early postoperative osteomyelitis and periprosthetic infections. The aim of this study was to verify specific uptake o
Autor:
Markus Hutterer, Karin Menhart, Hans-Jürgen Wester, Xin Lu, Dirk Hellwig, Bernhard Polzer, Peter Hau, Jirka Grosse, Daniel Heudobler, Benedikt Pregler, Michaela Bayerlová, Markus J. Riemenschneider, Stefan Hannus, Tim Beißbarth, Tobias Pukrop, Annalen Bleckmann, Saskia Kropf, Jutta Moosbauer, Raquel Blazquez, Florian Lüke, Rezan Fahrioglu Yamaci, Christoph Klein
Publikováno v:
Oncotarget. 9:18844-18857
Brain and leptomeningeal metastasis (LMM) of non-small cell lung cancer is still associated with poor prognosis. Moreover, the current diagnostic standard for LMM often yields false negative results and the scientific progress in this field is still
Autor:
Andreas Schirbel, Constantin Lapa, Katharina Lückerath, Stefan Kircher, Klaus Martin Kortüm, Andreas K. Buck, Antje Stolzenburg, Hermann Einsele, Andreas Rosenwald, Götz Ulrich Grigoleit, Saskia Kropf, Heribert Hänscheid, Hans-Jürgen Wester
Publikováno v:
British Journal of Haematology. 184:440-443
Autor:
James T. Thackeray, Hans-Juergen Wester, Thorsten Derlin, Tobias L. Ross, Saskia Kropf, Frank M. Bengel, Guenter Daum, Jan M Sohns, Desiree Weiberg
Publikováno v:
Journal of Nuclear Medicine. 59:266-272
The CXC-motif chemokine receptor 4 (CXCR4) represents a promising target for molecular imaging of different CXCR4-positive cell types in cardiovascular diseases such as atherosclerosis and arterial wall injury. The aim of this study was to assess the
Autor:
Birgit Meller, Caroline Bouter, Johannes Meller, Hans-Jürgen Wester, Wieland Staab, Carsten Oliver Sahlmann, Saskia Kropf
Publikováno v:
Journal of Nuclear Medicine. 59:320-326
Because of its role in infection and inflammatory processes, the chemokine receptor CXCR4 might be a potent target in imaging of infectious and inflammatory diseases. The aim of this pilot study was to determine whether the CXCR4 ligand 68Ga-pentixaf