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of 10
pro vyhledávání: '"Sasisekharan, Viswanathan"'
Autor:
Tharakaraman, Kannan, Subramanian, Vidya, Cain, David, Sasisekharan, Viswanathan, Sasisekharan, Ram
Publikováno v:
In Cell Host & Microbe 14 May 2014 15(5):644-651
Akademický článek
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Akademický článek
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Publikováno v:
Theoretica Chimica Acta; Jun1975, Vol. 38 Issue 2, p109-114, 6p
Publikováno v:
Theoretica Chimica Acta; June 1975, Vol. 38 Issue: 2 p109-114, 6p
Publikováno v:
Current Opinion in Structural Biology
PMC
PMC
The surfaces of host cells and viruses are decorated by complex glycans, which play multifaceted roles in the dynamic interplay between the virus and the host including viral entry into host cell, modulation of proteolytic cleavage of viral proteins,
Autor:
Tyree Koch, David Cain, Chong Wai Liew, Hamid Tissire, James R. Myette, Jianzhu Chen, Zachary Shriver, Gregory J. Babcock, Yee Hwa Wong, Julien Lescar, Sylvie Alonso, Rama Sanjay Kirloskar, Vivian Vasconcelos Costa, Kuan Rong Chan, Eng Eong Ooi, Luke Robinson, Kirk J. Rowley, Boopathy Ramakrishnan, Li Ching Ong, Viswanathan Sasisekharan, Ram Sasisekharan, Hwee Cheng Tan, Karthik Viswanathan, Kannan Tharakaraman
Publikováno v:
PMC
Dengue is the most common vector-borne viral disease, causing nearly 400 million infections yearly. Currently there are no approved therapies. Antibody epitopes that elicit weak humoral responses may not be accessible by conventional B cell panning m
Autor:
Zachary Shriver, Akila Jayaraman, Rahul Raman, Kannan Tharakaraman, Viswanathan Sasisekharan, Ram Sasisekharan
Publikováno v:
PMC
Influenza A viruses are rapidly evolving pathogens with the potential for novel strains to emerge and result in pandemic outbreaks in humans. Some avian-adapted subtypes have acquired the ability to bind to human glycan receptors and cause severe inf
Autor:
Viswanathan Sasisekharan, Ram Sasisekharan, Kannan Tharakaraman, David Cain, Vidya Subramanian
Publikováno v:
PMC
Broadly neutralizing antibodies (bNAb) that target a conserved region of a viral antigen hold significant therapeutic promise. CR8020 is a bNAb that targets the stem region of influenza A virus (IAV) hemagglutinin (HA). CR8020 is currently being eval
Autor:
Viswanathan Sasisekharan, Ram Sasisekharan, Nathan W. Stebbins, Karthik Viswanathan, Rahul Raman, Kannan Tharakaraman
Publikováno v:
Scientific Reports
Nature Publishing Group
Nature Publishing Group
The 2009 swine-origin H1N1 influenza, though antigenically novel to the population at the time, was antigenically similar to the 1918 H1N1 pandemic influenza, and consequently was considered to be “archived” in the swine species before reemerging