Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sasika N. Vithana Dewage"'
Autor:
Habtamu B. Derseh, Kopiyawaththage U. E. Perera, Sasika N. Vithana Dewage, Andrew Stent, Emmanuel Koumoundouros, Louise Organ, Charles N. Pagel, Ken J. Snibson
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Idiopathic pulmonary fibrosis (IPF) is a progressive chronic lung disease characterized by excessive extracellular matrix (ECM) deposition in the parenchyma of the lung. Accompanying the fibrotic remodeling, dysregulated angiogenesis has been observe
Externí odkaz:
https://doaj.org/article/bd205fb8776e4e3fa911e8440c80dcab
Autor:
Habtamu B. Derseh, Sasika N. Vithana Dewage, Kopiyawaththage U. E. Perera, Charles N. Pagel, Emmanuel Koumoundouros, Louise Organ, Ken J. Snibson
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease with limited therapeutic options and poor prognosis. IPF has been associated with aberrant vascular remodelling, however the role of vascular remodelling in pulmonary
Externí odkaz:
https://doaj.org/article/18bd2ab7a74e400796b59f1eeaf6c5b4
Autor:
Charles N. Pagel, Emmanuel Koumoundouros, Kenneth J. Snibson, Louise Organ, Sasika N. Vithana Dewage, Habtamu B Derseh, Udari Eshani Perera
Publikováno v:
Experimental Lung Research. 46:409-419
Background Although IPF is described traditionally as a disease affecting lung parenchyma, there is renewed interest in the alterations in the structure and function of the small airways in both IPF patients, and animal models of pulmonary fibrosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f900f1b3ae2cfe0eb72c86c35dab76
https://doi.org/10.1080/01902148.2020.1834015
https://doi.org/10.1080/01902148.2020.1834015
Autor:
Charles N. Pagel, Louise Organ, Kopiyawaththage U. E. Perera, Emmanuel Koumoundouros, Kenneth J. Snibson, Sasika N. Vithana Dewage, Habtamu B Derseh
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease with limited therapeutic options and poor prognosis. IPF has been associated with aberrant vascular remodelling, however the role of vascular remodelling in pulmonary fibrosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e9e0c07ee00abf209a71c2b2559df4
https://doaj.org/article/18bd2ab7a74e400796b59f1eeaf6c5b4
https://doaj.org/article/18bd2ab7a74e400796b59f1eeaf6c5b4
Autor:
Udari Eshani Perera, Kenneth J. Snibson, Habtamu B Derseh, Louise Organ, Andrew Stent, Sasika N. Vithana Dewage
Publikováno v:
Canadian Respiratory Journal, Vol 2021 (2021)
Background Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease, characterized by progressive damage to the lung tissues. Apoptosis and endoplasmic reticulum stress (ER stress) in type II alveolar epithelial cells (AECs) and lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::241e91b70e1d2e82007ebc16828da2b3
https://doi.org/10.21203/rs.3.rs-97842/v1
https://doi.org/10.21203/rs.3.rs-97842/v1
Autor:
Sasika N. Vithana Dewage, Emmanuel Koumoundouros, Kenneth J. Snibson, S. Royce, Louise Organ, Kopiyawaththage U. E. Perera, Habtamu B Derseh, Andrew Stent
Publikováno v:
A63. MEDIATORS OF LUNG FIBROSIS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66d9500e5ec8bd51b059ff9dd5a098ac
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2274
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2274
Autor:
Emmanuel Koumoundouros, Louise Organ, Kopiyawaththage U. E. Perera, Kenneth J. Snibson, Habtamu B Derseh, Chrishan S. Samuel, Andrew Stent, Sasika N. Vithana Dewage
Publikováno v:
Experimental lung research. 45(9-10)
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrotic lung disease with unknown cause. While the drugs nintedanib and pirfenidone have been approved for the treatment of IPF, they only slow disease progression and can induce several s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7fe3d9913082e5b367f6ab5b02feaa6
https://pubmed.ncbi.nlm.nih.gov/31762329
https://pubmed.ncbi.nlm.nih.gov/31762329
Autor:
Kenneth J. Snibson, K. Udari Eshani Perera, Louise Organ, Paul John Benham, Sasika N. Vithana Dewage, Andrew Stent, Habtamu B Derseh
Publikováno v:
Idiopathic interstitial pneumonias.
Background: ER stress in type II alveolar epithelial cells (AECs) and lung macrophages has been linked with the development of IPF. The KCa3.1 has been proposed as a novel target for IPF that activates cell types involved in the disease. While KCa3.1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eb6b17e305a51fcb2b03fb18635a4a8
https://doi.org/10.1183/13993003.congress-2019.pa5385
https://doi.org/10.1183/13993003.congress-2019.pa5385
Autor:
Sasika N. Vithana Dewage, Andrew Stent, Kenneth J. Snibson, K. Udari Eshani Perera, Louise Organ, Habtamu B Derseh
Publikováno v:
Idiopathic interstitial pneumonias.
Background: The K+ ion channel KCa3.1 is present on alveolar epithelial cells (AECs) and is known to activate other key cells involved in pulmonary fibrosis. While KCa3.1 has been proposed as a novel target for IPF, its regulatory function(s) in type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::427d2ebe6f1eeac2c02d00a53cdc80e5
https://doi.org/10.1183/13993003.congress-2018.pa3715
https://doi.org/10.1183/13993003.congress-2018.pa3715