Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Sashko Spassov"'
Autor:
Ulrich Goebel, Stefanie Scheid, Sashko Spassov, Nils Schallner, Jakob Wollborn, Hartmut Buerkle, Felix Ulbrich
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 1, Pp 192-198 (2021)
We previously found that argon exerts its neuroprotective effect in part by inhibition of the toll-like receptors (TLR) 2 and 4. The downstream transcription factors signal transducer and activator of transcription 3 (STAT3) and nuclear factor kappa
Externí odkaz:
https://doaj.org/article/b4df755a6a8849178e5c411abbfdb0ad
Autor:
Sashko Spassov, Dietmar Pfeifer, Karl Strosing, Stefan Ryter, Matthias Hummel, Simone Faller, Alexander Hoetzel
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102401 (2014)
Recently, we have shown that inhalation of hydrogen sulfide (H2S) protects against ventilator-induced lung injury (VILI). In the present study, we aimed to determine the underlying molecular mechanisms of H2S-dependent lung protection by analyzing ge
Externí odkaz:
https://doaj.org/article/6b95fbae333a40ed9977d2847b43c9ba
Autor:
Christian I Schwer, Cornelius Lehane, Timo Guelzow, Simone Zenker, Karl M Strosing, Sashko Spassov, Anika Erxleben, Bernd Heimrich, Hartmut Buerkle, Matjaz Humar
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77258 (2013)
Ischemic and traumatic brain injury is associated with increased risk for death and disability. The inhibition of penumbral tissue damage has been recognized as a target for therapeutic intervention, because cellular injury evolves progressively upon
Externí odkaz:
https://doaj.org/article/823258f309044594819056d4c582d633
Publikováno v:
Experimental Physiology. 106:396-400
What is the central question of the study? Does respiratory support ensure blood gas homeostasis and the relevance of experimental outcomes? What is the main finding and its importance? Spontaneous breathing during surgical intervention under anaesth
Autor:
Silke Borgmann, Kim Linz, Christian Braun, Patryk Dzierzawski, Sashko Spassov, Christin Wenzel, Stefan Schumann
Publikováno v:
Physiological measurement. 43(7)
Objective. Electrical impedance tomography is a valuable tool for monitoring global and regional lung mechanics. To evaluate the recorded data, an accurate estimate of the lung area is crucial. Approach. We present two novel methods for estimating th
Autor:
Ulrich Goebel, Nils Schallner, Hartmut Buerkle, Jakob Wollborn, Felix Ulbrich, Sashko Spassov, Stefanie Scheid
Publikováno v:
Neural Regeneration Research
Neural Regeneration Research, Vol 16, Iss 1, Pp 192-198 (2021)
Neural Regeneration Research, Vol 16, Iss 1, Pp 192-198 (2021)
We previously found that argon exerts its neuroprotective effect in part by inhibition of the toll-like receptors (TLR) 2 and 4. The downstream transcription factors signal transducer and activator of transcription 3 (STAT3) and nuclear factor kappa
Autor:
Sashko, Spassov, Christin, Wenzel, Sara, Lozano-Zahonero, Dimona, Boycheva, Lea, Streicher, Johannes, Schmidt, Stefan, Schumann
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Mechanical ventilation is associated with the risk of ventilator induced lung injury. For reducing lung injury in mechanically ventilated patients, the application of small tidal volumes and positive end-expiratory pressures has become clinical stand
Publikováno v:
Laboratory Animals. 54:568-575
For investigating the effects of mechanical ventilation on the respiratory system, experiments in small mammal models are used. However, conventional ventilators for small animals are usually limited to a specific ventilation mode, and in particular
Autor:
Stephan Meckel, Christin Wenzel, Stefan Schumann, Sebastian Eiden, Jakob Wollborn, Johannes Schmidt, Steffen Wirth, S. Borgmann, Sashko Spassov, Jonas Weber, Ziwei Lin, Jörg Haberstroh
Publikováno v:
Critical Care Medicine
Supplemental Digital Content is available in the text.
Objectives: Lung-protective ventilation for acute respiratory distress syndrome aims for providing sufficient oxygenation and carbon dioxide clearance, while limiting the harmful effects of
Objectives: Lung-protective ventilation for acute respiratory distress syndrome aims for providing sufficient oxygenation and carbon dioxide clearance, while limiting the harmful effects of
Autor:
Stefan Schumann, Johannes Schmidt, Christin Wenzel, Gerald Urban, Sashko Spassov, Johannes Lengerer
Publikováno v:
European journal of anaesthesiology. 39(1)