Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Sashko Damjanovski"'
Publikováno v:
Current Research in Physiology, Vol 5, Iss , Pp 344-354 (2022)
In teleosts, cardiac plasticity plays a central role in mediating thermal acclimation. Previously, we demonstrated that exposure to elevated temperatures throughout development (+4°C) improved acute thermal tolerance of the heart in juvenile Atlanti
Externí odkaz:
https://doaj.org/article/be8452bfe7714902bb8e834efed03da7
Publikováno v:
Journal of Biological Research - Thessaloniki, Vol 26, Iss 1, Pp 1-10 (2019)
Abstract Background MT1-MMP is a cell-surface enzyme whose regulation of pro-MMP-2 and ERK activation position it as a key facilitator of ECM remodelling and cell migration. These processes are modulated by endogenous MMP inhibitors, such as RECK, a
Externí odkaz:
https://doaj.org/article/a3a1b255b7d342ac94a0b298a9f2765c
Autor:
Sashko Damjanovski
Publikováno v:
All Results Journals: Biol, Vol 5, Iss 4, Pp 30-36 (2014)
Extracellular matrix (ECM) remodeling is accomplished largely by matrix metalloproteinases (MMPs), which cleave individual components of the ECM to facilitate cell migration. Tissue inhibitors of metalloproteinases (TIMPs) are secreted MMP inhibitors
Externí odkaz:
https://doaj.org/article/45a16c0bca494ef9bca943e1a6f4465e
Publikováno v:
The Journal of experimental biology. 225(16)
In many fishes, upper thermal tolerance is thought to be limited in part by the heart's ability to meet increased oxygen demands during periods of high temperature. Temperature-dependent plasticity within the cardiovascular system may help fish cope
Publikováno v:
Current research in physiology. 5
In teleosts, cardiac plasticity plays a central role in mediating thermal acclimation. Previously, we demonstrated that exposure to elevated temperatures throughout development (+4°C) improved acute thermal tolerance of the heart in juvenile Atlanti
Publikováno v:
Paediatrics Publications
Conservation Physiology
Conservation Physiology
Small rodent pulse-wave Doppler echocardiograph systems can be adapted for use in juvenile salmonids to measure metrics of cardiac function relevant to thermal performance, including maximum heart rate, ventricular filling volume, Arrhenius breakpoin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166c79cc08d808c7f73f739916708575
https://ir.lib.uwo.ca/context/paedpub/article/2056/viewcontent/coab070.pdf
https://ir.lib.uwo.ca/context/paedpub/article/2056/viewcontent/coab070.pdf
Publikováno v:
PLoS ONE, Vol 2, Iss 10, p e1000 (2007)
Matrix metalloproteinases (MMPs) and their endogenous inhibitors TIMPs (tissue inhibitors of MMPs), are two protein families that work together to remodel the extracellular matrix (ECM). TIMPs serve not only to inhibit MMP activity, but also aid in t
Externí odkaz:
https://doaj.org/article/7ee8f42f60594d3f82c000d1256fd31e
Publikováno v:
Paediatrics Publications
The membrane bound matrix metalloproteinase MT1-MMP plays roles in modulating cell movement, independent of its abilities to remodel the extracellular matrix. Unlike many MMPs, MT1-MMP is activated in the Golgi prior to secretion by a pro-protein con
Publikováno v:
Journal of Biological Research-Thessaloniki, Vol 26, Iss 1, Pp 1-10 (2019)
Paediatrics Publications
Paediatrics Publications
Background MT1-MMP is a cell-surface enzyme whose regulation of pro-MMP-2 and ERK activation position it as a key facilitator of ECM remodelling and cell migration. These processes are modulated by endogenous MMP inhibitors, such as RECK, a GPI-ancho
Publikováno v:
Journal of Scientific Research and Reports. 6:504-513
Aims: Reversion - inducing cysteine - rich protein with Kazal motifs (RECK) is a membrane - anchored protein that regulates cell migration by both inhibiting matrix metalloproteinases and modulating cellular pathways. Our study is the first to clone