Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sashika N. Richards"'
Autor:
Sarah H. Shafik, Simon A. Cobbold, Kawthar Barkat, Sashika N. Richards, Nicole S. Lancaster, Manuel Llinás, Simon J. Hogg, Robert L. Summers, Malcolm J. McConville, Rowena E. Martin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Plasmodium falciparum chloroquine resistance transporter (PfCRT) mediates multidrug resistance, but its natural function remains unclear. Here, Shafik et al. show that PfCRT transports host-derived peptides of 4-11 residues but not other ions or meta
Externí odkaz:
https://doaj.org/article/e62a9cfeb1b74e3793184dbfb72b16f7
Autor:
Vicky Zhang, Robert Kucharski, Courtney Landers, Sashika N. Richards, Stefan Bröer, Rowena E. Martin, Ryszard Maleszka
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Dopamine is an important neuromodulator involved in reward-processing, movement control, motivational responses, and other aspects of behavior in most animals. In honey bees (Apis mellifera), the dopaminergic system has been implicated in an elaborat
Externí odkaz:
https://doaj.org/article/20f8e7c6d3f944c7907faaaef43fb3c0
Autor:
Sashika N Richards, Megan N Nash, Eileen S Baker, Michael W Webster, Adele M Lehane, Sarah H Shafik, Rowena E Martin
Publikováno v:
PLoS Pathogens, Vol 12, Iss 7, p e1005725 (2016)
Mutations in the Plasmodium falciparum 'chloroquine resistance transporter' (PfCRT) confer resistance to chloroquine (CQ) and related antimalarials by enabling the protein to transport these drugs away from their targets within the parasite's digesti
Externí odkaz:
https://doaj.org/article/c5c24d1b429c4890955f2192f5a69ecb
Autor:
Sashika N. Richards, Courtney Landers, Stefan Bröer, Robert Kucharski, Vicky Zhang, Ryszard Maleszka, Rowena E. Martin
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Frontiers in Physiology
Frontiers in Physiology
Dopamine is an important neuromodulator involved in reward-processing, movement control, motivational responses, and other aspects of behaviour in most animals. In honey bees (Apis mellifera), the dopaminergic system has been implicated in an elabora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e85e8c54bb9dabb0b987bb1d7326b7
https://doi.org/10.3389/fphys.2019.01375
https://doi.org/10.3389/fphys.2019.01375
Autor:
Nicole S. Lancaster, Manuel Llinás, Sarah H. Shafik, Robert L. Summers, Simon J. Hogg, Malcolm J. McConville, Kawthar Barkat, Rowena E. Martin, Simon A. Cobbold, Sashika N. Richards
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The Plasmodium falciparum chloroquine resistance transporter (PfCRT) is a key contributor to multidrug resistance and is also essential for the survival of the malaria parasite, yet its natural function remains unresolved. We identify host-derived pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c80cce56587a46440b3acf33d9e412
https://pubmed.ncbi.nlm.nih.gov/32764664
https://pubmed.ncbi.nlm.nih.gov/32764664
Publikováno v:
Current opinion in pharmacology. 42
The deployment of artemisinin-based combination therapies (ACTs) has been, and continues to be, integral to reducing the number of malaria cases and deaths. However, their efficacy is being increasingly jeopardized by the emergence and spread of para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839b2fec47f8ce6629f75ef6f5d11e61
https://pubmed.ncbi.nlm.nih.gov/30142480
https://pubmed.ncbi.nlm.nih.gov/30142480
Autor:
Adele M. Lehane, Megan N. Nash, Michael W. Webster, Rowena E. Martin, Sarah H. Shafik, Sashika N. Richards, Eileen S. Baker
Publikováno v:
PLoS Pathogens, Vol 12, Iss 7, p e1005725 (2016)
PLoS Pathogens
PLoS Pathogens
Mutations in the Plasmodium falciparum ‘chloroquine resistance transporter’ (PfCRT) confer resistance to chloroquine (CQ) and related antimalarials by enabling the protein to transport these drugs away from their targets within the parasite’s d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b372c98b8b856597f2eec4f8e4c66c94
https://doaj.org/article/c5c24d1b429c4890955f2192f5a69ecb
https://doaj.org/article/c5c24d1b429c4890955f2192f5a69ecb
Autor:
Michael Lanzer, Robert L. Summers, Sashika N. Richards, Wilfred D. Stein, Kiaran Kirk, Rowena E. Martin, Megan N. Nash, Tegan J. Dolstra, Valerie Goh, Rosa V. Marchetti, Cecilia P. Sanchez, Anurag Dave, Robyn L. Schenk, Sebastiano Bellanca
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 111(17)
Mutations in the chloroquine resistance transporter (PfCRT) are the primary determinant of chloroquine (CQ) resistance in the malaria parasite Plasmodium falciparum. A number of distinct PfCRT haplotypes, containing between 4 and 10 mutations, have g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470f4f89904721c142909720d0127c19
https://pubmed.ncbi.nlm.nih.gov/24728833
https://pubmed.ncbi.nlm.nih.gov/24728833
Autor:
Toyoyuki Ose, E. Yvonne Jones, Nicholas E. Dixon, Carola G. Vinuesa, Anil Verma, Thomas Preiss, Monika Srivastava, Janet H. C. Yeo, Desheng Hu, Vicki Athanasopoulos, Vigo Heissmeyer, Hardip R. Patel, Guowen Duan, Slobodan Jergic, Sashika N. Richards, Nadia J. Kershaw, Simon H. J. Brown, Alvin Pratama, Jeffrey J. Babon, Mark M.W. Chong
Publikováno v:
'Nature Communications ', vol: 6, pages: 6253-1-6253-13 (2015)
Nature Communications
Nature Communications
Roquin is an RNA-binding protein that prevents autoimmunity and inflammation via repression of bound target mRNAs such as inducible costimulator (Icos). When Roquin is absent or mutated (Roquinsan), Icos is overexpressed in T cells. Here we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd38cfc8cd317efcbf697b655973eacf
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:41392
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:41392