Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sasha V. Siegel"'
Autor:
Sasha V. Siegel, Hidayat Trimarsanto, Roberto Amato, Kathryn Murie, Aimee R. Taylor, Edwin Sutanto, Mariana Kleinecke, Georgia Whitton, James A. Watson, Mallika Imwong, Ashenafi Assefa, Awab Ghulam Rahim, Hoang Chau Nguyen, Tinh Hien Tran, Justin A. Green, Gavin C. K. W. Koh, Nicholas J. White, Nicholas Day, Dominic P. Kwiatkowski, Julian C. Rayner, Ric N. Price, Sarah Auburn
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Challenges in classifying recurrent Plasmodium vivax infections constrain surveillance of antimalarial efficacy and transmission. Recurrent infections may arise from activation of dormant liver stages (relapse), blood-stage treatment failure
Externí odkaz:
https://doaj.org/article/9bc856d4342e4495a19575b3200d2f4d
Autor:
Alebachew Messele Kebede, Edwin Sutanto, Hidayat Trimarsanto, Ernest Diez Benavente, Mariana Barnes, Richard D. Pearson, Sasha V. Siegel, Berhanu Erko, Ashenafi Assefa, Sisay Getachew, Abraham Aseffa, Beyene Petros, Eugenia Lo, Rezika Mohammed, Daniel Yilma, Angela Rumaseb, Francois Nosten, Rintis Noviyanti, Julian C. Rayner, Dominic P. Kwiatkowski, Ric N. Price, Lemu Golassa, Sarah Auburn
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Ethiopia has the greatest burden of Plasmodium vivax in Africa, but little is known about the epidemiological landscape of parasites across the country. We analysed the genomic diversity of 137 P. vivax isolates collected nine Ethiopian dist
Externí odkaz:
https://doaj.org/article/5386a2335ef64870878c33d75df801c1
Autor:
Sasha V. Siegel, Lia Chappell, Jessica B. Hostetler, Chanaki Amaratunga, Seila Suon, Ulrike Böhme, Matthew Berriman, Rick M. Fairhurst, Julian C. Rayner
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Plasmodium vivax gene regulation remains difficult to study due to the lack of a robust in vitro culture method, low parasite densities in peripheral circulation and asynchronous parasite development. We adapted an RNA-seq protocol “DAFT-s
Externí odkaz:
https://doaj.org/article/c2c28e9b7b754adc9f200b9d0768dd5b
Autor:
William R. Proto, Sasha V. Siegel, Selasi Dankwa, Weimin Liu, Alison Kemp, Sarah Marsden, Zenon A. Zenonos, Steve Unwin, Paul M. Sharp, Gavin J. Wright, Beatrice H. Hahn, Manoj T. Duraisingh, Julian C. Rayner
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Here, Proto et al. show that human infective Plasmodium falciparum isolates contain an inactivating mutation in the erythrocyte invasion associated gene PfEBA165, while homologues of ape-infective Laverania species are intact, and that expression of
Externí odkaz:
https://doaj.org/article/bd6dae0de5d54fc5a18cf05d76370dba
Autor:
William R. Proto, Sasha V. Siegel, Selasi Dankwa, Weimin Liu, Alison Kemp, Sarah Marsden, Zenon A. Zenonos, Steve Unwin, Paul M. Sharp, Gavin J. Wright, Beatrice H. Hahn, Manoj T. Duraisingh, Julian C. Rayner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21491-y
Externí odkaz:
https://doaj.org/article/b9c1748601c04e268745fb1c8395b462
Autor:
Sasha V. Siegel, Roberto Amato, Hidayat Trimarsanto, Edwin Sutanto, Mariana Kleinecke, Kathryn Murie, Georgia Whitton, Aimee R. Taylor, James A. Watson, Mallika Imwong, Ashenafi Assefa, Awab Ghulam Rahim, Nguyen Hoang Chau, Tran Tinh Hien, Justin A Green, Gavin Koh, Nicholas J. White, Nicholas Day, Dominic P. Kwiatkowski, Julian C. Rayner, Ric N. Price, Sarah Auburn
Publikováno v:
medRxiv
Challenges in understanding the origin of recurrentPlasmodium vivaxinfections constrains the surveillance of antimalarial efficacy and transmission of this neglected parasite. Recurrent infections within an individual may arise from activation of dor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6564af58973cb23fa03869b3febfeb3
https://europepmc.org/articles/PMC10055443/
https://europepmc.org/articles/PMC10055443/
Autor:
Ishag, Adam, Mohammad Shafiul, Alam, Sisay, Alemu, Chanaki, Amaratunga, Roberto, Amato, Voahangy, Andrianaranjaka, Nicholas M, Anstey, Abraham, Aseffa, Elizabeth, Ashley, Ashenafi, Assefa, Sarah, Auburn, Bridget E, Barber, Alyssa, Barry, Dhelio, Batista Pereira, Jun, Cao, Nguyen Hoang, Chau, Kesinee, Chotivanich, Cindy, Chu, Arjen M, Dondorp, Eleanor, Drury, Diego F, Echeverry, Berhanu, Erko, Fe, Espino, Rick, Fairhurst, Abdul, Faiz, María, Fernanda Villegas, Qi, Gao, Lemu, Golassa, Sonia, Goncalves, Matthew J, Grigg, Yaghoob, Hamedi, Tran Tinh, Hien, Ye, Htut, Kimberly J, Johnson, Nadira, Karunaweera, Wasif, Khan, Srivicha, Krudsood, Dominic P, Kwiatkowski, Marcus, Lacerda, Benedikt, Ley, Pharath, Lim, Yaobao, Liu, Alejandro, Llanos-Cuentas, Chanthap, Lon, Tatiana, Lopera-Mesa, Jutta, Marfurt, Pascal, Michon, Olivo, Miotto, Rezika, Mohammed, Ivo, Mueller, Chayadol, Namaik-Larp, Paul N, Newton, Thuy-Nhien, Nguyen, Francois, Nosten, Rintis, Noviyanti, Zuleima, Pava, Richard D, Pearson, Beyene, Petros, Aung P, Phyo, Ric N, Price, Sasithon, Pukrittayakamee, Awab Ghulam, Rahim, Milijaona, Randrianarivelojosia, Julian C, Rayner, Angela, Rumaseb, Sasha V, Siegel, Victoria J, Simpson, Kamala, Thriemer, Alberto, Tobon-Castano, Hidayat, Trimarsanto, Marcelo, Urbano Ferreira, Ivan D, Vélez, Sonam, Wangchuk, Thomas E, Wellems, Nicholas J, White, Timothy, William, Maria F, Yasnot, Daniel, Yilma
Publikováno v:
Wellcome open research. 7
This report describes the MalariaGEN Pv4 dataset, a new release of curated genome variation data on 1,895 samples of
Autor:
Manoj T. Duraisingh, Alison Kemp, Julian C. Rayner, Selasi Dankwa, William R. Proto, Paul M. Sharp, Gavin J. Wright, Zenon A. Zenonos, Steve Unwin, Weimin Liu, Sasha V. Siegel, Sarah Marsden, Beatrice H. Hahn
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Proto, W R, Siegel, S V, Dankwa, S, Liu, W, Kemp, A, Marsden, S, Zenonos, Z A, Unwin, S, Sharp, P M, Wright, G J, Hahn, B H, Duraisingh, M T & Rayner, J C 2019, ' Adaptation of Plasmodium falciparum to humans involved the loss of an ape-specific erythrocyte invasion ligand ', Nature Communications, vol. 10, 4512 . https://doi.org/10.1038/s41467-019-12294-3
Nature Communications
Proto, W R, Siegel, S V, Dankwa, S, Liu, W, Kemp, A, Marsden, S, Zenonos, Z A, Unwin, S, Sharp, P M, Wright, G J, Hahn, B H, Duraisingh, M T & Rayner, J C 2019, ' Adaptation of Plasmodium falciparum to humans involved the loss of an ape-specific erythrocyte invasion ligand ', Nature Communications, vol. 10, 4512 . https://doi.org/10.1038/s41467-019-12294-3
Plasmodium species are frequently host-specific, but little is currently known about the molecular factors restricting host switching. This is particularly relevant for P. falciparum, the only known human-infective species of the Laverania sub-genus,
Autor:
Andrea V. Rivero, Isaure de Buron, Dennis E. Kyle, Beatrice L. Colon, Jenna Oberstaller, Sasha V. Siegel
Publikováno v:
International Journal for Parasitology. 48:1097-1106
Life cycles of spirorchiids that infect the vascular system of turtles are poorly understood. Few life cycles of these blood flukes have been elucidated and all intermediate hosts reported are gastropods (Mollusca), regardless of whether the definiti
Autor:
Seila Suon, Sasha V. Siegel, Matthew Berriman, Rick M. Fairhurst, Chanaki Amaratunga, Ulrike Böhme, Julian C. Rayner, Lia Chappell, Jessica B. Hostetler
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Plasmodium vivax gene regulation remains difficult to study due to the lack of a robust in vitro culture method, low parasite densities in peripheral circulation and asynchronous parasite development. We adapted an RNA-seq protocol “DAFT-seq” to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01d90098c5aa62b9f49674543261699